{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T07:52:27Z","timestamp":1758959547479},"reference-count":23,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T00:00:00Z","timestamp":1658188800000},"content-version":"vor","delay-in-days":48,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Nucl Med"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Gallbladder cancer has a poor prognosis and imaging can have variable diagnostic accuracy. We assessed the ability of preoperative 18F-fluorodeoxyglucose positron emission tomography computed tomography (18F-FDG-PET\/CT) imaging to predict a postoperative histological diagnosis of gallbladder cancer.<\/jats:p><jats:p>\n          Method\u2003A retrospective analysis was undertaken in a cohort of patients, who had suspected gallbladder cancer on cross-sectional imaging and that underwent preoperative FDG-PET\/CT scan. The discriminatory power of FDG-PET\/CT was determined in receiver operator characteristic (ROC) analysis and diagnostic accuracy parameters were estimated at different thresholds of maximum standard unit value (SUVmax).\n        <\/jats:p><jats:p>\n          Results\u2003Twenty-two patients were included in the study; 7 had malignant and 15 benign diagnoses. There was no statistically significant difference between the measured SUVmax between the two groups (p\u2009=\u20090.71). With an area under the curve of 0.486, the ROC curve did not indicate any discriminatory power of FDG-PET\/CT at any potential threshold of SUVmax.\n        <\/jats:p><jats:p>\n          Conclusion\u2003This study indicates that the diagnosis of primary gallbladder cancer cannot be accurately confirmed with FDG PET\/CT scanning.<\/jats:p>","DOI":"10.1055\/s-0042-1750332","type":"journal-article","created":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T22:39:39Z","timestamp":1658270379000},"page":"112-119","source":"Crossref","is-referenced-by-count":7,"title":["The Diagnostic Accuracy of 18F-FGD-PET\/CT for Cancer of the Gallbladder: A Retrospective Study"],"prefix":"10.1055","volume":"21","author":[{"given":"Stephanos","family":"Pericleous","sequence":"additional","affiliation":[{"name":"Department of HPB Surgery, Academic Department of Surgery, Royal Marsden Hospital, London, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie L. F.","family":"Doran","sequence":"additional","affiliation":[{"name":"Department of HPB Surgery, Academic Department of Surgery, Royal Marsden Hospital, London, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Wotherspoon","sequence":"additional","affiliation":[{"name":"Department of Histopathology, Royal Marsden Hospital, London, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica","family":"Terlizzo","sequence":"additional","affiliation":[{"name":"Department of Histopathology, Royal Marsden Hospital, London, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Riddell","sequence":"additional","affiliation":[{"name":"Department of Radiology and Nuclear Medicine, Royal Marsden Hospital, London, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gina","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Radiology and Nuclear Medicine, Royal Marsden Hospital, London, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua","family":"Shur","sequence":"additional","affiliation":[{"name":"Department of Radiology and Nuclear Medicine, Royal Marsden Hospital, London, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sue","family":"Chua","sequence":"additional","affiliation":[{"name":"Department of Radiology and Nuclear Medicine, Royal Marsden Hospital, London, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nabil","family":"Hujairi","sequence":"additional","affiliation":[{"name":"Department of Radiology and Nuclear Medicine, Royal Marsden Hospital, London, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicos","family":"Middleton","sequence":"additional","affiliation":[{"name":"School of Health Sciences, Cyprus University of Technology, Limassol, Cyprus"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Cunningham","sequence":"additional","affiliation":[{"name":"Department of Oncology, Royal Marsden Hospital, London, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sacheen","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Surgery, Academic Department of Surgery, Royal Marsden Hospital, London, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricky H.","family":"Bhogal","sequence":"additional","affiliation":[{"name":"Department of HPB Surgery, Academic Department of Surgery, Royal Marsden Hospital, London, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,7,19]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"394","DOI":"10.3322\/caac.21492","article-title":"Global cancer statistics 2018: GLOBOCAN 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