{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:33:24Z","timestamp":1792175604834,"version":"4.4.0"},"reference-count":26,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T00:00:00Z","timestamp":1661299200000},"content-version":"vor","delay-in-days":84,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian J Neurosurg"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objectives\u2003Cerebral vasospasm in subarachnoid hemorrhage (SAH) is associated with high morbidity and mortality. There is a lack of consensus on the risk factors leading to cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage (aSAH). In this retrospective study, our objective was to determine the association of risk factors for cerebral vasospasm aSAH.<\/jats:p><jats:p>\n          Methods\u2003A total of 259 charts of aSAH patients consecutively admitted to the surgical intensive care unit of Hamad General Hospital from January 2007 to December 2016 were reviewed and included. The patient's demographic data, including comorbidities like hypertension (HTN), was recorded. Variables of interest included measurements of the neurological deficit on admission, the severity of SAH, treatment modality, and the initial computerized tomography scan of the head for intraventricular hemorrhage, intracerebral hemorrhage, or hydrocephalus. Multivariate analysis and multiple logistic regression analyzed the relationship to identify the association of independent variables.<\/jats:p><jats:p>\n          Results\u2003Out of the 259 patients, 34% (n\u2009=\u200987) suffered from cerebral vasospasm. The severity of SAH was associated with the development of cerebral vasospasm (p\u2009&lt;\u20090.05). The presence of HTN and neurological deficits on admission were associated with an increased risk of cerebral vasospasm (p\u2009&lt;\u20090.05, p\u2009&lt;\u20090.01, respectively). Hydrocephalus requiring treatment using external ventricular drains decreased the risk of cerebral vasospasm (p\u2009&lt;\u20090.05). Intraventricular and intracerebral hemorrhage were not associated with cerebral vasospasm (p\u2009=\u20090.25, p\u2009=\u20090.16). The endovascular treatment of cerebral aneurysms was associated with an increased risk of cerebral vasospasm (p\u2009&lt;\u20090.05).<\/jats:p><jats:p>\n          Conclusion\u2003Cerebral vasospasm is common among patients admitted with aSAH. It is significantly associated with the history of HTN, the neurological deficit on admission that corelates more strongly to the motor deficit on admission, the severity of hemorrhage (modified Fischer score), and endovascular treatment. External ventricular drainage was associated with a decrease in cerebral vasospasm. The present study's findings shed light on cerebral vasospasm's risk factors in the country and the region.<\/jats:p>","DOI":"10.1055\/s-0042-1750838","type":"journal-article","created":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T23:16:08Z","timestamp":1661382968000},"page":"242-247","source":"Crossref","is-referenced-by-count":12,"title":["Risk Factors for Cerebral Vasospasm in Patients with Aneurysmal Subarachnoid Hemorrhage: A Tertiary Care Center Experience"],"prefix":"10.1055","volume":"17","author":[{"given":"Muhammad Mohsin","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nissar","family":"Shaikh","sequence":"additional","affiliation":[{"name":"Surgical Intensive Care Unit, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zohaib","family":"Yousaf","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hussain","family":"Sultan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Sadek","sequence":"additional","affiliation":[{"name":"Weill Cornell Medicine, Education City, Al Luqta St, Ar-Rayyan, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adnan","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saadat","family":"Kamran","sequence":"additional","affiliation":[{"name":"Weill Cornell Medicine, Education City, Al Luqta St, Ar-Rayyan, Qatar"},{"name":"Department of Neurology, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayman Z.","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Neurology, Hamad Medical Corporation, Doha, Qatar"},{"name":"Department of Neurosurgery, Neuroscience Institute, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walid","family":"Albanna","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, RWTH Aachen University, Aachen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sirajeddin","family":"Belkhair","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Hamad Medical Corporation, Doha, Qatar"},{"name":"Department of Neurosurgery, Neuroscience Institute, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Ayyad","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Neuroscience Institute, Hamad Medical Corporation, Doha, Qatar"},{"name":"Department of Neurosurgery, Saarland University Hospital, Homburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,8,24]]},"reference":[{"issue":"08","key":"ref1","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1161\/STROKEAHA.116.012957","article-title":"Sex, smoking, and risk for subarachnoid hemorrhage","volume":"47","author":"J V Lindbohm","year":"2016","journal-title":"Stroke"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"e100","DOI":"10.1016\/j.wneu.2017.10.089","article-title":"Subarachnoid hemorrhage and readmissions: national rates, causes, risk factors, and outcomes in 16,001 hospitalized patients","volume":"110","author":"K 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Pluta","year":"2009","journal-title":"Neurol Res"},{"issue":"06","key":"ref9","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.3171\/2009.9.JNS081670","article-title":"Association of a younger age with an increased risk of angiographic and symptomatic vasospasms following subarachnoid hemorrhage","volume":"112","author":"S N Magge","year":"2010","journal-title":"J Neurosurg"},{"issue":"12","key":"ref10","doi-asserted-by":"crossref","first-page":"e0168657","DOI":"10.1371\/journal.pone.0168657","article-title":"Incidence and predictors of angiographic vasospasm, symptomatic vasospasm and cerebral infarction in Chinese patients with aneurysmal subarachnoid hemorrhage","volume":"11","author":"M Mijiti","year":"2016","journal-title":"PLoS One"},{"issue":"01","key":"ref11","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s41983-018-0050-y","article-title":"Vasospasm following aneurysmal subarachnoid hemorrhage: prediction, detection, and 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Inagawa","year":"2016","journal-title":"World Neurosurg"},{"issue":"04","key":"ref15","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1227\/NEU.0b013e3181ed1379","article-title":"Intraventricular hemorrhage volume predicts poor outcomes but not delayed ischemic neurological deficits among patients with ruptured cerebral aneurysms","volume":"67","author":"A H Kramer","year":"2010","journal-title":"Neurosurgery"},{"key":"ref16","first-page":"175","article-title":"Predictors analysis of symptomatic cerebral vasospasm after subarachnoid hemorrhage","volume":"110","author":"L Yin","year":"2011","journal-title":"Acta Neurochir Suppl (Wien)"},{"issue":"06","key":"ref17","doi-asserted-by":"crossref","first-page":"465","DOI":"10.2176\/nmc.oa.2013-0169","article-title":"Risk factors associated with cerebral vasospasm following aneurysmal subarachnoid hemorrhage","volume":"54","author":"T Inagawa","year":"2014","journal-title":"Neurol Med Chir (Tokyo)"},{"issue":"06","key":"ref18","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1161\/STROKEAHA.108.544700","article-title":"Defining vasospasm after subarachnoid hemorrhage: what is the most clinically relevant definition?","volume":"40","author":"J A Frontera","year":"2009","journal-title":"Stroke"},{"issue":"10","key":"ref19","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1111\/cns.13202","article-title":"New risk score of the early period after spontaneous subarachnoid hemorrhage: for the prediction of delayed cerebral ischemia","volume":"25","author":"Y J Fang","year":"2019","journal-title":"CNS Neurosci Ther"},{"issue":"05","key":"ref20","doi-asserted-by":"crossref","first-page":"882","DOI":"10.3171\/jns.2005.102.5.0882","article-title":"Decrease in platelet count as an independent risk factor for symptomatic vasospasm following aneurysmal subarachnoid hemorrhage","volume":"102","author":"Y Hirashima","year":"2005","journal-title":"J 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Ibrahim","year":"2012","journal-title":"Neurosurgery"}],"container-title":["Asian Journal of 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