{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T13:19:30Z","timestamp":1770815970662,"version":"3.50.1"},"reference-count":10,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2022,7,31]],"date-time":"2022-07-31T00:00:00Z","timestamp":1659225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Radiol Imaging"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Neurovascular conflicts (NVCs) are one of the major causative factors in patients presenting with trigeminal neuralgia (TN). We found a wide range of variation in degrees of acute angle formed between medial border of trigeminal nerve and anterior border of pons in patients with TN, i.e., medial trigeminopontine angle (mTPA), and tried to find its correlation with pain severity due to NVC over the medial aspect of nerve (mNVC).<\/jats:p><jats:p>\n          Aims and Objectives\u2003To correlate mTPA measurement with severity of TN due to mNVC. To calculate the reduction in pain in patients kept on medical management and its correlation with mTPA.<\/jats:p><jats:p>\n          Materials and Methods\u2003This was a retrospective observational study conducted between May 2018 and October 2020. A total of 41 patients presenting with TN and showing corresponding NVC were included in the study. Out of the total cases with NVC, 30 cases showed NVC over the medial surface of the nerve. All the patients were evaluated on MAGNETOM Skyra 3T magnetic resonance imaging (MRI; Siemens). Using the two-line Cobb angle method, the trigeminopontine angle was calculated. Pretreatment pain intensity and posttreatment pain relief of each patients were assessed by using the numeric rating scale (NRS) with numbers from 0 to 10 (\u201cno pain\u201d to \u201cworst pain imaginable\u201d). Relevant clinical details regarding pre- and posttreatment pain score, after a standard treatment plan of 600\u2009mg of oxcarbazepine for 2 weeks, were collected.<\/jats:p><jats:p>\n          Results\u2003Patients showing response of more than or equal to 50% (\u226550%) are considered as \u201cgood response\u201d and those with response of less than 50% (&lt;50%) are considered as \u201cpoor response.\u201d In our study with trigeminopontine angle threshold of 45\u2009degrees, 7 out of 8 (87.5%) patients with &gt;45\u00b0 mTPA showed poor response and 15\/22 (68.2%) patients with \u226445\u00b0 showed good response to medical management for TN with statistical significance difference with a p-valve of 0.007.<\/jats:p><jats:p>\n          Conclusion\u2003We found a negative correlation between the mTPA and percentage pain relief in patients kept on medical management and realized that mTPA measurement could become an important tool for prognosticating pain relief for patients of TN on medical therapy; however, more evidence and multicentric studies are required for the same.<\/jats:p>","DOI":"10.1055\/s-0042-1753468","type":"journal-article","created":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T05:13:01Z","timestamp":1659330781000},"page":"308-313","source":"Crossref","is-referenced-by-count":1,"title":["Correlation of Trigeminopontine Angle with Severity of Trigeminal Neuralgia due to Neurovascular Conflict over Medial Aspect of Nerve: Can We Prognosticate the Reduction in Pain in Patients on Medical Management?"],"prefix":"10.1055","volume":"32","author":[{"given":"Pundalik Umalappa","family":"Lamani","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imageology, Nizam's Institute Of Medical Sciences, Hyderabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhishek J.","family":"Arora","sequence":"additional","affiliation":[{"name":"Department of Radio-Diagnosis, All India Institute of Medical Sciences, Bibinagar, Hyderabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiran Kumar Reddy","family":"Kona","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imageology, Nizam's Institute Of Medical Sciences, Hyderabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jyotsna","family":"Yarlagadda","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imageology, Nizam's Institute Of Medical Sciences, Hyderabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,7,31]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1148\/radiographics.15.4.7569130","article-title":"Trigeminal neuropathy: evaluation with MR imaging","volume":"15","author":"C B 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sequences for detection of neurovascular conflicts in patients with trigeminal neuralgia and predictive value for characterization of the conflict (particularly degree of vascular compression) [in French]","volume":"56","author":"P R Leal","year":"2010","journal-title":"Neurochirurgie"},{"issue":"02","key":"ref9","doi-asserted-by":"crossref","first-page":"631","DOI":"10.3171\/2018.9.JNS181768","article-title":"Sex-dependent posterior fossa anatomical differences in trigeminal neuralgia patients with and without neurovascular compression: a volumetric MRI age- and sex-matched case-control study","volume":"132","author":"F A Hardaway","year":"2019","journal-title":"J Neurosurg"},{"issue":"01","key":"ref10","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/bja\/aen103","article-title":"Assessment of pain","volume":"101","author":"H Breivik","year":"2008","journal-title":"Br J Anaesth"}],"container-title":["Indian Journal of Radiology and 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