{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T12:07:03Z","timestamp":1762085223257,"version":"build-2065373602"},"reference-count":19,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T00:00:00Z","timestamp":1680048000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Introduction\u2003Otosclerosis is a common cause of conductive hearing loss in the adult population that is caused by fixation of the stapes footplate. Cochlear otosclerosis may also present with sensorineural or mixed hearing loss. Surgery is the definitive treatment of choice and, during the procedure, sealing of the oval window with autologous tissue graft around the stapes prosthesis has been routinely done to improve hearing outcome and to mitigate postoperative complications.<\/jats:p><jats:p>\n          Objective\u2003To evaluate the efficacy of two different types of autologous tissue (vein or fat) grafts as oval window sealing materials in stapedotomy in improving short-term hearing outcomes.<\/jats:p><jats:p>\n          Methods\u2003In our study, 70 patients with otosclerosis who underwent primary stapedotomy were included. They were divided into group 1 (vein graft) and group 2 (fat graft) based on the type of sealing material used. All patients were followed-up at the end of 3 months, undergoing an audiometric examination to assess the hearing outcome.<\/jats:p><jats:p>\n          Results\u2003A total of 80% (n\u2009=\u200928) of the patients in group1 had an air-bone gap (ABG) closure\u2009&lt;\u200910dB, and, in group 2, 85.7% had an ABG closure\u2009&lt;\u200910\u2009dB; this difference was found to be statistically insignificant. A total of 42.9% (n\u2009=\u200915) of the patients in group 1 and of 31.4% (n\u2009=\u200911) in group 2 had a significant improvement in bone conduction, while 14.3% (n\u2009=\u20095) of the patients in group 1 and 17.1% (n\u2009=\u20096) in group 2 had worsening of average bone conduction postoperatively, which was found to be statistically insignificant.<\/jats:p><jats:p>\n          Conclusion\u2003Both vein and fat grafts had comparable effects on hearing outcomes when used as sealing materials in stapedotomy.<\/jats:p>","DOI":"10.1055\/s-0042-1754343","type":"journal-article","created":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T23:41:10Z","timestamp":1680133270000},"page":"e226-e233","source":"Crossref","is-referenced-by-count":2,"title":["Comparison of Short-Term Hearing Outcome in Stapedotomy Using either Vein or Fat (Adipose Tissue) as Sealing Material"],"prefix":"10.1055","volume":"27","author":[{"given":"Anand","family":"Velusamy","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Muthur Chinnasamy Velusamy (MCV) Memorial ENT Trust Hospital, Pollachi, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Kavithadevi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Muthur Chinnasamy Velusamy (MCV) Memorial ENT Trust Hospital, Pollachi, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5669-3075","authenticated-orcid":false,"given":"Nazrin","family":"Hameed","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Muthur Chinnasamy Velusamy (MCV) Memorial ENT Trust Hospital, Pollachi, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3908-6310","authenticated-orcid":false,"given":"Aishwarya","family":"Anand","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Muthur Chinnasamy Velusamy (MCV) Memorial ENT Trust Hospital, Pollachi, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,3,29]]},"reference":[{"key":"ref1","first-page":"122","article-title":"Otosclerosis","volume":"70","author":"M Ealy","year":"2011","journal-title":"Adv Otorhinolaryngol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.heares.2009.07.002","article-title":"The genetics of otosclerosis","volume":"266","author":"M Ealy","year":"2010","journal-title":"Hear Res"},{"issue":"11","key":"ref3","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1288\/00005537-198511000-00003","article-title":"Histologic variants in otosclerosis","volume":"95","author":"H F Schuknecht","year":"1985","journal-title":"Laryngoscope"},{"issue":"05","key":"ref4","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1288\/00005537-197405000-00008","article-title":"Cochlear otosclerosis: fact or fantasy","volume":"84","author":"H F Schuknecht","year":"1974","journal-title":"Laryngoscope"},{"key":"ref5","first-page":"529","volume-title":"Surgery of the Ear","author":"G E Shambaugh","year":"1959"},{"issue":"02","key":"ref6","first-page":"230","article-title":"Vein graft in stapes surgery","volume":"17","author":"S A Kamal","year":"1996","journal-title":"Am J Otol"},{"issue":"04","key":"ref7","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1177\/000348945806700403","article-title":"Fenestration of the oval window","volume":"67","author":"J J Shea Jr","year":"1958","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"02","key":"ref8","first-page":"112","article-title":"Stapedotomy versus stapedectomy","volume":"4","author":"U Fisch","year":"1982","journal-title":"Am J Otol"},{"issue":"07","key":"ref9","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1097\/MAO.0000000000001117","article-title":"Stapedotomy With Adipose Tissue Seal: Hearing Outcomes, Incidence of Sensorineural Hearing Loss, and Comparison to Alternative Techniques","volume":"37","author":"K F Lin","year":"2016","journal-title":"Otol Neurotol"},{"key":"ref10","first-page":"206","article-title":"Advantages and risks of various sealing procedures of the oval window: vein graft, adipose tissue, gelfoam, merogel","volume":"65","author":"A Incesulu","year":"2007","journal-title":"Adv Otorhinolaryngol"},{"issue":"01","key":"ref11","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1177\/0194599812463184","article-title":"Hearing outcomes in stapes surgery: a comparison of fat, fascia, and vein tissue seals","volume":"148","author":"R J Wiet","year":"2013","journal-title":"Otolaryngol Head Neck Surg."},{"issue":"02","key":"ref12","first-page":"173","article-title":"Survival and evolution of vein grafts in otosclerosis surgery: structural and ultrastructural evidence","volume":"13","author":"A Lopez","year":"1992","journal-title":"Am J Otol"},{"issue":"05","key":"ref13","first-page":"392","article-title":"Technique for otosclerosis","volume":"5","author":"J B Causse","year":"1984","journal-title":"Am J Otol"},{"issue":"01","key":"ref14","first-page":"68","article-title":"Stapedotomy technique and results","volume":"6","author":"J B Causse","year":"1985","journal-title":"Am J Otol"},{"issue":"01","key":"ref15","first-page":"75","article-title":"The twenty fine points of otosclerosis surgery","volume":"10","author":"J B Causse","year":"1989","journal-title":"Am J Otol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1097\/01.mao.0000235311.80066.df","article-title":"Surgical findings and long-term hearing results in 3,050 stapedotomies for primary otosclerosis: a prospective study with the otology-neurotology database","volume":"27","author":"R Vincent","year":"2006","journal-title":"Otol Neurotol"},{"issue":"05","key":"ref17","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1097\/MAO.0b013e31828bb523","article-title":"A nonrandomized comparison of stapes surgery with and without a vein graft in patients with otosclerosis","volume":"34","author":"A JN Bittermann","year":"2013","journal-title":"Otol Neurotol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1288\/00005537-199212000-00001","article-title":"Laser stapedotomy: a comparative study of prostheses and seals","volume":"102","author":"R Perkins","year":"1992","journal-title":"Laryngoscope"},{"issue":"05","key":"ref19","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1097\/00129492-200409000-00008","article-title":"Vein versus tragal perichondrium in stapedotomy","volume":"25","author":"S Schmerber","year":"2004","journal-title":"Otol Neurotol"}],"container-title":["International Archives of Otorhinolaryngology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0042-1754343.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T23:35:46Z","timestamp":1682724946000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0042-1754343"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,29]]},"references-count":19,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2023,4,28]]},"published-print":{"date-parts":[[2023,4]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0042-1754343","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1809-9777","1809-4864"],"issn-type":[{"type":"print","value":"1809-9777"},{"type":"electronic","value":"1809-4864"}],"subject":[],"published":{"date-parts":[[2023,3,29]]}}}