{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T16:17:43Z","timestamp":1740154663897,"version":"3.37.3"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2022,8,30]],"date-time":"2022-08-30T00:00:00Z","timestamp":1661817600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Radiol Imaging"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A brown tumor is one of the manifestations of hyperparathyroidism. It is a rare type of bone lesion that most often occurs in mandible, ribs, and large bones. Spinal involvement is extremely rare. We report an unusual case of a brown tumor of the axis vertebra in a 33-year-old male who presented to the orthopaedic clinic with posttraumatic C2 vertebra fracture and myelopathy. To plan further fixation and stabilization of C2 fracture, the patient underwent a plain radiograph and magnetic resonance imaging (MRI) of the cervical spine. The available routine chest radiograph at the time of MRI reporting clinched the diagnosis of primary hyperparathyroidism with a brown tumor of the axis vertebra. Thus, familiarity with subtle radiographic findings of this condition not only led to early diagnosis and appropriate treatment but also avoided unnecessary C2 biopsy and hardware fixation.<\/jats:p>","DOI":"10.1055\/s-0042-1755266","type":"journal-article","created":{"date-parts":[[2022,8,30]],"date-time":"2022-08-30T22:55:05Z","timestamp":1661900105000},"page":"615-620","source":"Crossref","is-referenced-by-count":0,"title":["A Rare Case of Primary Hyperparathyroidism Presenting as a C2 Brown Tumor-Plain Radiography Has yet again Proved Indispensable in Clinching the Diagnosis"],"prefix":"10.1055","volume":"32","author":[{"given":"Jyoti","family":"Panwar","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Christian Medical College and Hospital, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tameem A.","family":"Bhat","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Christian Medical College and Hospital, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saket","family":"Ballabh","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Christian Medical College and Hospital, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepak","family":"Abraham","sequence":"additional","affiliation":[{"name":"Department of Endocrine Surgery, Christian Medical College, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5903-6110","authenticated-orcid":false,"given":"Felix K.","family":"Jebasingh","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Diabetes and Metabolism, Christian Medical College and Hospital, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,8,30]]},"reference":[{"issue":"02","key":"ref1","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s00402-007-0312-0","article-title":"A case of multiple skeletal lesions of brown tumors, mimicking carcinoma metastases","volume":"128","author":"M Hoshi","year":"2008","journal-title":"Arch Orthop Trauma Surg"},{"issue":"04","key":"ref2","doi-asserted-by":"crossref","first-page":"752","DOI":"10.2214\/ajr.160.4.8456657","article-title":"Brown tumor","volume":"160","author":"F S Chew","year":"1993","journal-title":"AJR Am J Roentgenol"},{"issue":"01","key":"ref3","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0033-8389(22)02680-X","article-title":"Hyperparathyroidism","volume":"29","author":"C W Hayes","year":"1991","journal-title":"Radiol Clin North Am"},{"issue":"19","key":"ref4","doi-asserted-by":"crossref","first-page":"E557","DOI":"10.1097\/BRS.0b013e3181453f85","article-title":"Unusual spinal manifestation in secondary hyperparathyroidism: a case report","volume":"32","author":"W Jackson","year":"2007","journal-title":"Spine"},{"issue":"08","key":"ref5","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/s00256-004-0803-9","article-title":"Radicular lower extremity pain as the first symptom of primary hyperparathyroidism","volume":"33","author":"A O Mustonen","year":"2004","journal-title":"Skeletal Radiol"},{"issue":"03","key":"ref6","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s10067-010-1608-y","article-title":"Brown tumor of the cervical spine: a case report and review of the literature","volume":"30","author":"L Mateo","year":"2011","journal-title":"Clin Rheumatol"},{"issue":"01","key":"ref7","doi-asserted-by":"crossref","first-page":"110","DOI":"10.4184\/asj.2015.9.1.110","article-title":"Brown tumor of the cervical spines: a case report with literature review","volume":"9","author":"M D Alfawareh","year":"2015","journal-title":"Asian Spine J"},{"issue":"02","key":"ref8","doi-asserted-by":"crossref","first-page":"185","DOI":"10.3109\/00365597809179990","article-title":"Secondary hyperparathyroidism combined with uremia and giant cell containing tumor of the cervical spine. 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