{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:15:10Z","timestamp":1787004910317,"version":"build-2736575974"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"07","license":[{"start":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T00:00:00Z","timestamp":1664409600000},"content-version":"vor","delay-in-days":90,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Neuropsiquiatr"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>To celebrate the 400th anniversary of the birth of Thomas Willis, his main contributions to the development of neurosciences, in particular neurology, are presented. Willis coined the term neurology and contributed significantly to the field of neuroanatomy, with the description of the arterial circle\u2014located at the base of the brain\u2014, which bears his name. He also described the striatum and cranial nerves. Furthermore, as a clinical neurologist, Willis participated in the description of various diseases, including myasthenia gravis and restless legs syndrome.<\/jats:p>","DOI":"10.1055\/s-0042-1755278","type":"journal-article","created":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T18:30:24Z","timestamp":1664476224000},"page":"759-762","source":"Crossref","is-referenced-by-count":7,"title":["Thomas Willis' legacy on the 400th anniversary of his birth"],"prefix":"10.1055","volume":"80","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2305-1073","authenticated-orcid":false,"given":"H\u00e9lio Afonso Ghizoni","family":"Teive","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1, Hospital de Cl\u00ednicas, Departamento de Cl\u00ednica M\u00e9dica, Servi\u00e7o de Neurologia, Curitiba PR, Brazil."},{"name":"Universidade Federal do Paran\u00e1, Hospital de Cl\u00ednicas, Departamento de Cl\u00ednica M\u00e9dica, Grupo de Doen\u00e7as Neurodegenerativas, Programa de P\u00f3s-gradua\u00e7\u00e3o em Medicina Interna, Curitiba, Curitiba PR, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4921-2939","authenticated-orcid":false,"given":"L\u00e9o","family":"Coutinho","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1, Hospital de Cl\u00ednicas, Departamento de Cl\u00ednica M\u00e9dica, Servi\u00e7o de Neurologia, Curitiba PR, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3533-0347","authenticated-orcid":false,"given":"Carlos Henrique Ferreira","family":"Camargo","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1, Hospital de Cl\u00ednicas, Departamento de Cl\u00ednica M\u00e9dica, Grupo de Doen\u00e7as Neurodegenerativas, Programa de P\u00f3s-gradua\u00e7\u00e3o em Medicina Interna, Curitiba, Curitiba PR, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4783-4067","authenticated-orcid":false,"given":"Renato Puppi","family":"Munhoz","sequence":"additional","affiliation":[{"name":"University of Toronto, Toronto Western Hospital, Division of Neurology, Morton and Gloria Shulman Movement Disorders Centre and Edmond J. Safra Program in Parkinson's Disease, Toronto, Ontario, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6927-7946","authenticated-orcid":false,"given":"Olivier","family":"Walusinski","sequence":"additional","affiliation":[{"name":"Private Practice, Brou, France."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,9,29]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1093\/brain\/awab016","article-title":"On the 400th anniversary of the birth of Thomas Willis","volume":"144","author":"Z Moln\u00e1r","year":"2021","journal-title":"Brain"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/joa.12273","article-title":"Thomas Willis, a pioneer in translational research in anatomy (on the 350th anniversary of Cerebri anatome)","volume":"226","author":"L A Arr\u00e1ez-Aybar","year":"2015","journal-title":"J Anat"},{"key":"ref3","first-page":"1","volume-title":"The beginnings of neurology: Thomas Willis and his circle of friends","author":"W Feindel","year":"1999"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1093\/oso\/9780195065039.001.0001","volume-title":"A history of explorations into brain function","author":"S Finger","year":"1994"},{"key":"ref5","volume-title":"Thomas Willis 1621\u20131675: His life and Works","author":"J T Hughes","year":"2009","edition":"2nd edition"},{"issue":"03","key":"ref6","doi-asserted-by":"crossref","first-page":"277","DOI":"10.4997\/JRCPE.2010.318","article-title":"Cerebri anatome: Thomas Willis and his circle","volume":"40","author":"I ML Donaldson","year":"2010","journal-title":"J R Coll Physicians Edinb"},{"issue":"06","key":"ref7","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1227\/01.NEU.0000327691.40686.AA","article-title":"Thomas Willis of the \u201ccircle of Willis\u201d","volume":"63","author":"K A Choudhari","year":"2008","journal-title":"Neurosurgery"},{"issue":"06","key":"ref8","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/0022-510X(64)90172-8","article-title":"A note on Thomas Willis'views on the corpus striatum and the internal capsule","volume":"1","author":"T Willis","year":"1964","journal-title":"J Neurol Sci"},{"issue":"04","key":"ref9","doi-asserted-by":"crossref","first-page":"765","DOI":"10.3171\/JNS\/2008\/109\/10\/0765","article-title":"The legendary contributions of Thomas Willis (1621-1675): the arterial circle and beyond","volume":"109","author":"S S Rengachary","year":"2008","journal-title":"J Neurosurg"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/S0072-9752(08)02139-8","article-title":"Chapter 39: an historical overview of British neurology","volume":"95","author":"F C Rose","year":"2010","journal-title":"Handb Clin Neurol"},{"issue":"12","key":"ref11","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/j.nmd.2005.08.007","article-title":"The early history of myasthenia gravis","volume":"15","author":"T Hughes","year":"2005","journal-title":"Neuromuscul Disord"},{"key":"ref12","volume-title":"The London practice of physick","author":"T Willis","year":"1685"},{"issue":"02","key":"ref13","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1136\/jnnp.71.2.143","article-title":"Restless legs syndrome","volume":"71","author":"K R Chaudhuri","year":"2001","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"08","key":"ref14","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.sleep.2014.03.025","article-title":"Restless legs syndrome\/Willis-Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria\u2013history, rationale, description, and significance","volume":"15","author":"R P Allen","year":"2014","journal-title":"Sleep Med"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.bandc.2014.08.005","article-title":"Thomas Willis: the faculties and his two cognitive frameworks","volume":"91","author":"J McNabb","year":"2014","journal-title":"Brain Cogn"},{"issue":"03","key":"ref16","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1177\/09677720211000728","article-title":"\u2018To unlock the secret places of Man's Mind\u2019","volume":"30","author":"P Hunting","year":"2022","journal-title":"Thomas Willis (1621\u20131675). Journal of Medical Biography"},{"key":"ref17","volume-title":"Father of English Neurology","author":"M Critchley","year":"1998"},{"key":"ref18","volume-title":"Exploring the Victorian brain","author":"A Scott","year":"2021"},{"key":"ref19","doi-asserted-by":"crossref","DOI":"10.1093\/oso\/9780195076431.001.0001","volume-title":"Constructing Neurology","author":"C G Goetz","year":"1995"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1590\/S0004-282X2001000200032","article-title":"Charcot and Brazil","volume":"59","author":"H AG Teive","year":"2001","journal-title":"Arq Neuropsiquiatr"}],"container-title":["Arquivos de Neuro-Psiquiatria"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0042-1755278.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T23:27:24Z","timestamp":1701127644000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0042-1755278"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":20,"journal-issue":{"issue":"07","published-online":{"date-parts":[[2022,9,29]]},"published-print":{"date-parts":[[2022,7]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0042-1755278","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0004-282X","1678-4227"],"issn-type":[{"value":"0004-282X","type":"print"},{"value":"1678-4227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7]]}}}