{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T22:37:09Z","timestamp":1783118229901,"version":"3.54.6"},"reference-count":37,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2022,10,26]],"date-time":"2022-10-26T00:00:00Z","timestamp":1666742400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Plast Surg"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003The objective of our study was to derive an objective assessment scale for three-dimensional (3D) qualitative and quantitative evaluation of secondary alveolar bone grafting (SABG) using cone-bone computed tomography (CBCT) in patients with unilateral cleft lip and palate (UCLP).<\/jats:p><jats:p>\n          Methods\u2003CBCT scans for pre- and 3-month post-SABG were reviewed for bone volume, height, width, and density of the bony bridge formed in the cleft defect in 20 patients with UCLP. Basic descriptive and principal component analysis was used to extract the various sub-components of the scale. Spearman's correlation was used to check the validity of the scale, and intra-class coefficient (ICC) and Cronbach's \u03b1 were calculated to establish the reliability and retest applicability of the scale.<\/jats:p><jats:p>\n          Results\u2003Each CBCT scan was assessed in five areas: cementoenamel junction (CEJ), root apex, root midpoint, 3 and 6\u2009mm below CEJ, and tabulated in percentiles of 20, 25, 40, 50, 60, and 75 for all the parameters (bone volume, density, and width). These scores were validated when correlated to the scale given by Kamperos et al. Cronbach's \u03b1 for the domains demonstrated acceptable to excellent internal consistency. The ICC showed good test\u2013retest reliability having a range of scores from 0.89 to 0.94.<\/jats:p><jats:p>\n          Conclusion\u2003The proposed scale for the 3D assessment of SABG in patients with UCLP provides gradation for the objective assessment of the bony bridge. This gradation enables the qualitative and quantitative assessments of the bony bridge, thus allowing each clinician to judge SABG more conclusively.<\/jats:p>","DOI":"10.1055\/s-0042-1756137","type":"journal-article","created":{"date-parts":[[2022,10,26]],"date-time":"2022-10-26T22:56:22Z","timestamp":1666824982000},"page":"138-146","source":"Crossref","is-referenced-by-count":6,"title":["A Three-Dimensional Scale for the Qualitative and Quantitative Assessments of Secondary Alveolar Bone Grafting (SABG) in Unilateral Cleft Lip and Palate Patients Using Cone-Beam Computed Tomography (CBCT)"],"prefix":"10.1055","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5525-4794","authenticated-orcid":false,"given":"Ashish","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics, Institute of Dental Sciences and Technologies, Modinagar, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puneet","family":"Batra","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics, Manav Rachna Dental College, Faridabad, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karan","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics, Institute of Dental Sciences and Technologies, Modinagar, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sreevatsan","family":"Raghavan","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics, Institute of Dental Sciences and Technologies, Modinagar, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditya","family":"Talwar","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics, Manav Rachna Dental College, Faridabad, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics, Institute of Dental Sciences and Technologies, Modinagar, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sundereshwer Chander","family":"Sood","sequence":"additional","affiliation":[{"name":"Smile Train Centre, Sant Parmanand Hospital, Civil Lines, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,10,26]]},"reference":[{"issue":"03","key":"ref1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/nrg2933","article-title":"Cleft lip and palate: understanding genetic and environmental influences","volume":"12","author":"M J Dixon","year":"2011","journal-title":"Nat Rev Genet"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1016\/S0140-6736(09)60695-4","article-title":"Cleft lip and palate","volume":"374","author":"P A Mossey","year":"2009","journal-title":"Lancet"},{"issue":"01","key":"ref3","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.jormas.2020.07.010","article-title":"Effectiveness of presurgical orthodontics in cleft lip and palate patients with alveolar bone grafting: a systematic review","volume":"122","author":"L Ma","year":"2021","journal-title":"J Stomatol Oral Maxillofac Surg"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"23597","DOI":"10.1038\/srep23597","article-title":"Difference in the surgical outcome of unilateral cleft lip and palate patients with and without pre-alveolar bone graft orthodontic treatment","volume":"6","author":"C-S Chang","year":"2016","journal-title":"Sci Rep"},{"issue":"02","key":"ref5","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1590\/S1678-77572012000200024","article-title":"Rehabilitative treatment of cleft lip and palate: experience of the hospital for rehabilitation of craniofacial anomalies-USP (HRAC-USP)\u2014part 2: pediatric dentistry and orthodontics","volume":"20","author":"J A Freitas","year":"2012","journal-title":"J Appl Oral Sci"},{"issue":"02","key":"ref6","first-page":"87","article-title":"Secondary bone grafting of residual alveolar and palatal clefts","volume":"30","author":"P J Boyne","year":"1972","journal-title":"J Oral Surg"},{"issue":"02","key":"ref7","first-page":"127","article-title":"Secondary bone grafting of alveolar clefts. A surgical\/orthodontic treatment enabling a non-prosthodontic rehabilitation in cleft lip and palate patients","volume":"15","author":"F E Abyholm","year":"1981","journal-title":"Scand J Plast Reconstr Surg"},{"issue":"05","key":"ref8","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.ajodo.2019.11.012","article-title":"Comparison of dental outcomes in patients with nonsyndromic complete unilateral cleft lip and palate who receive secondary alveolar bone grafting before or after emergence of the permanent maxillary canine","volume":"157","author":"Y R Vandersluis","year":"2020","journal-title":"Am J Orthod Dentofacial Orthop"},{"issue":"03","key":"ref9","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1053\/j.sodo.2017.05.003","article-title":"The orthodontist's role in the management of patients with cleft lip and palate undergoing alveolar bone grafting","volume":"23","author":"J O Wirthlin","year":"2017","journal-title":"Semin Orthod"},{"issue":"07","key":"ref10","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/S0007-1226(03)00361-8","article-title":"Assessment of secondary alveolar bone grafting using a modification of the Bergland grading system","volume":"56","author":"P J Hynes","year":"2003","journal-title":"Br J Plast Surg"},{"issue":"04","key":"ref11","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.bjoms.2007.12.010","article-title":"Three-dimensional evaluation of secondary alveolar bone grafting using a 3D-navigation system based on computed tomography: a two-year follow-up","volume":"46","author":"M Feichtinger","year":"2008","journal-title":"Br J Oral Maxillofac Surg"},{"issue":"02","key":"ref12","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1597\/03-035.1","article-title":"Application of limited cone beam computed tomography to clinical assessment of alveolar bone grafting: a preliminary report","volume":"42","author":"Y Hamada","year":"2005","journal-title":"Cleft Palate Craniofac J"},{"issue":"05","key":"ref13","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1597\/08-153.1","article-title":"Volumetric assessment of secondary alveolar bone grafting using cone beam computed tomography","volume":"46","author":"S Oberoi","year":"2009","journal-title":"Cleft Palate Craniofac J"},{"issue":"01","key":"ref14","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jcms.2015.09.003","article-title":"Evaluation of success of alveolar cleft bone graft performed at 5 years versus 10 years of age","volume":"44","author":"C Dissaux","year":"2016","journal-title":"J Craniomaxillofac Surg"},{"issue":"02","key":"ref15","doi-asserted-by":"crossref","first-page":"74","DOI":"10.4103\/jclpca.jclpca_7_18","article-title":"Clinical utility of cone-beam computed tomography in patients with cleft lip palate: current perspectives and guidelines","volume":"5","author":"S Parveen","year":"2018","journal-title":"J Cleft Lip Palate Craniofacial Anomalies"},{"issue":"04","key":"ref16","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1007\/s10278-012-9562-7","article-title":"Impact of voxel size variation on CBCT-based diagnostic outcome in dentistry: a systematic review","volume":"26","author":"R Spin-Neto","year":"2013","journal-title":"J Digit Imaging"},{"issue":"04","key":"ref17","doi-asserted-by":"crossref","first-page":"501","DOI":"10.2334\/josnusd.53.501","article-title":"Comparative assessment of subjective image quality of cross-sectional cone-beam computed tomography scans","volume":"53","author":"K Kamburo\u011flu","year":"2011","journal-title":"J Oral Sci"},{"issue":"01","key":"ref18","doi-asserted-by":"crossref","first-page":"20180047","DOI":"10.1259\/dmfr.20180047","article-title":"Three-dimensional radiological evaluation of secondary alveolar bone grafting in cleft lip and palate patients: a systematic review","volume":"48","author":"D De Mulder","year":"2018","journal-title":"Dentomaxillofac Radiol"},{"issue":"04","key":"ref19","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.jcms.2019.01.013","article-title":"Current methods for secondary alveolar bone grafting assessment in cleft lip and palate patients\u2014a systematic review","volume":"47","author":"M Stasiak","year":"2019","journal-title":"J Craniomaxillofac Surg"},{"issue":"04","key":"ref20","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.oooo.2020.04.815","article-title":"Comparison of 2- and 3-dimensional radiologic evaluation of secondary alveolar bone grafting of clefts: a systematic review","volume":"130","author":"X Yu","year":"2020","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"issue":"01","key":"ref21","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1597\/02-119.4.1","article-title":"The Eurocleft study: intercenter study of treatment outcome in patients with complete cleft lip and palate. 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