{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T23:25:21Z","timestamp":1794007521425,"version":"4.8.0"},"reference-count":24,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"12","license":[{"start":{"date-parts":[[2022,9,22]],"date-time":"2022-09-22T00:00:00Z","timestamp":1663804800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003The aim of this study was to evaluate the use of vaginal molds, made with three-dimensional (3D) printing, for conservative treatment through vaginal dilation in patients with vaginal agenesis (VA).<\/jats:p><jats:p>\n          Methods\u2003A total of 16 patients with a diagnosis of VA (Mayer-Rokitansky-K\u00fcster-Hauser syndrome, total androgen insensitivity syndrome, and cervicovaginal agenesis) from the Federal University of S\u00e3o Paulo were selected. Device production was performed in a 3D printer, and the polymeric filament of the lactic polyacid (PLA) was used as raw material. A personalized treatment was proposed and developed for each patient.<\/jats:p><jats:p>\n          Results\u2003There were 14 patients who reached a final vaginal length of 6\u2009cm or more. The initial total vaginal length (TVL) mean (SD) was 1.81(1.05) and the final TVL mean (SD) was 6.37 (0.94); the difference, analyzed as 95% confidence interval (95% CI) was 4.56 (5.27\u20133.84) and the effect size (95% CI) was 4.58 (2.88\u20136.28).<\/jats:p><jats:p>\n          Conclusion\u2003The 3D printing molds for vaginal dilation were successful in 87.5% of the patients. They did not present any major adverse effects and offered an economical, accessible, and reproducible strategy for the treatment of VA.<\/jats:p>","DOI":"10.1055\/s-0042-1756214","type":"journal-article","created":{"date-parts":[[2022,9,23]],"date-time":"2022-09-23T03:58:28Z","timestamp":1663905508000},"page":"1110-1116","source":"Crossref","is-referenced-by-count":8,"title":["Three-dimensional Printer Molds for Vaginal Agenesis: An Individualized Approach as Conservative Treatment"],"prefix":"10.61622","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0943-9573","authenticated-orcid":false,"given":"Marina Silva","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Escola Paulista de Medicina, Universidade Federal de S\u00e3o Paulo, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5698-0245","authenticated-orcid":false,"given":"Claudia Cristina","family":"Takano","sequence":"additional","affiliation":[{"name":"Escola Paulista de Medicina, Universidade Federal de S\u00e3o Paulo, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2908-5215","authenticated-orcid":false,"given":"Thyeres Teixeira Bueno","family":"Chrispin","sequence":"additional","affiliation":[{"name":"Escola Paulista de Medicina, Universidade Federal de S\u00e3o Paulo, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4573-5361","authenticated-orcid":false,"given":"Gisele Vissoci","family":"Marquini","sequence":"additional","affiliation":[{"name":"Escola Paulista de Medicina, Universidade Federal de S\u00e3o Paulo, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1206-9377","authenticated-orcid":false,"given":"Manoel Jo\u00e3o Batista Castello","family":"Gir\u00e3o","sequence":"additional","affiliation":[{"name":"Escola Paulista de Medicina, Universidade Federal de S\u00e3o Paulo, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3001-6076","authenticated-orcid":false,"given":"Marair Gracio Ferreira","family":"Sartori","sequence":"additional","affiliation":[{"name":"Escola Paulista de Medicina, Universidade Federal de S\u00e3o Paulo, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"47794","published-online":{"date-parts":[[2022,9,22]]},"reference":[{"issue":"02","key":"ref1","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1111\/cge.12883","article-title":"Genetics of Mayer-Rokitansky-K\u00fcster-Hauser (MRKH) syndrome","volume":"91","author":"L Fontana","year":"2017","journal-title":"Clin 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