{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T12:25:04Z","timestamp":1792844704097,"version":"4.5.0"},"reference-count":15,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2022,10,7]],"date-time":"2022-10-07T00:00:00Z","timestamp":1665100800000},"content-version":"vor","delay-in-days":36,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian J Neurosurg"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Kleine\u2013Levin syndrome (KLS) is a rare central disorder of daytime hypersomnolence and is often characterized by a relapsing and remitting course, recurrent episodes of excessive sleep lasting from 12 to 20\u2009hours a day, and symptoms including hyperphagia, hallucinations, derealization, disorientation, and hypersexuality. There are numerous perioperative considerations in dealing with KLS that include challenges during induction of anesthesia, delayed emergence, postoperative sleep disorders, and delirium. However, due to its rare occurrence, the anesthetic considerations of KLS remain poorly described. This case report outlines the anesthetic considerations and management of a young female patient with KLS who underwent transnasal excision of a trigeminal schwannoma under general anesthesia.<\/jats:p>","DOI":"10.1055\/s-0042-1756624","type":"journal-article","created":{"date-parts":[[2022,10,7]],"date-time":"2022-10-07T19:05:52Z","timestamp":1665169552000},"page":"480-484","source":"Crossref","is-referenced-by-count":3,"title":["Perioperative Considerations in a Patient with Kleine\u2013Levin Syndrome Undergoing a Neurosurgical Procedure under General Anesthesia"],"prefix":"10.1055","volume":"17","author":[{"given":"Wesley","family":"Rajaleelan","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Pain Management, University Health Network, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada"},{"name":"Department of Anesthesia and Pain Management, Women's College Hospital, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tumul","family":"Chowdhury","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Pain Management, University Health Network, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada"},{"name":"Department of Anesthesia and Pain Management, Women's College Hospital, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Moga","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Pain Management, University Health Network, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada"},{"name":"Department of Anesthesia and Pain Management, Women's College Hospital, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"Todaro","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Pain Management, University Health Network, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada"},{"name":"Department of Anesthesia and Pain Management, Women's College Hospital, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gelareh","family":"Zadeh","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University Health Network, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University Health Network, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mandeep","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Pain Management, University Health Network, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada"},{"name":"Department of Anesthesia and Pain Management, Women's College Hospital, Toronto, Ontario, Canada"},{"name":"Toronto Sleep and Pulmonary Centre, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,10,7]]},"reference":[{"key":"ref1","first-page":"96","volume-title":"Kleine Levin Syndrome","author":"I Arnulf","year":"2016"},{"issue":"05","key":"ref2","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1097\/00004691-200009000-00012","article-title":"Multiple sleep latency test and polysomnography in diagnosing Kleine-Levin syndrome and periodic hypersomnia","volume":"17","author":"F Rosenow","year":"2000","journal-title":"J Clin Neurophysiol"},{"issue":"09","key":"ref3","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1213\/XAA.0000000000000481","article-title":"Case report of a patient with idiopathic hypersomnia and a family history of malignant hyperthermia 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