{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T05:16:54Z","timestamp":1668575814956},"reference-count":22,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T00:00:00Z","timestamp":1665532800000},"content-version":"vor","delay-in-days":41,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian J Neurosurg"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Chordomas are aggressive and invasive tumors that are notoriously famous for their recurrence and metastasis. They present with diverse manifestations, usually with lower cranial nerve involvement. Here, we present the first reported case of chondroid chordoma with femur metastasis. A 71-year-old lady presented to us with a headache and diplopia. MRI of the brain revealed an enhanced broad and destructive mass in the infrasellar region with complete destruction of the clivus, right cavernous sinus. She underwent multiple surgeries along with gamma knife and proton therapy. The patient later presented with a trochanteric fracture and needed a hip replacement. Biopsy curettage of the femur lesion revealed a chondroid chordoma of the femur. The patient died later of a chest infection. Multimodality treatment is required in chordoma management, including surgery, gamma knife, and proton therapy. A firm discerning eye is required in the elderly toward metastatic spread to the femur in cases presenting with fractures of long bones.<\/jats:p>","DOI":"10.1055\/s-0042-1756629","type":"journal-article","created":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T23:08:11Z","timestamp":1665616091000},"page":"536-540","source":"Crossref","is-referenced-by-count":0,"title":["Chordoma of the Clivus with Metastasis to Femur"],"prefix":"10.1055","volume":"17","author":[{"given":"Maruf","family":"Matmusaev","sequence":"additional","affiliation":[{"name":"Department od Skull Base Surgery, Republican Specialized Scientific Practical Medical Center of Neurosurgery, Republic of Uzbekistan, Tashkent, Uzbekistan"},{"name":"Department of Neurosurgery, Center of Neuroendoscopy, Nagoya Daini Red Cross Hospital, Nagoya, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuya","family":"Nagatani","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Center of Neuroendoscopy, Nagoya Daini Red Cross Hospital, Nagoya, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yugo","family":"Kishida","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Center of Neuroendoscopy, Nagoya Daini Red Cross Hospital, Nagoya, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Ansari","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India"},{"name":"Deparment of Neurosurgery, Fujita Health University Banbuntane Hospital, Nagoya, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,10,12]]},"reference":[{"issue":"07","key":"ref1","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1007\/s00701-003-0057-7","article-title":"Intradural spinal seeding of a clival chordoma","volume":"145","author":"S Asano","year":"2003","journal-title":"Acta Neurochir (Wien)"},{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"e69","DOI":"10.1016\/S1470-2045(11)70337-0","article-title":"Chordoma: current concepts, management, and future directions","volume":"13","author":"B P Walcott","year":"2012","journal-title":"Lancet Oncol"},{"issue":"02","key":"ref3","doi-asserted-by":"crossref","first-page":"182","DOI":"10.3171\/jns.1997.86.2.0182","article-title":"Skull base chordomas: a management challenge","volume":"86","author":"O al-Mefty","year":"1997","journal-title":"J Neurosurg"},{"issue":"03","key":"ref4","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.surneu.2009.01.003","article-title":"Intradural cranial chordoma","volume":"73","author":"E Ito","year":"2010","journal-title":"World Neurosurg"},{"issue":"03","key":"ref5","doi-asserted-by":"crossref","first-page":"508","DOI":"10.3171\/jns.1991.74.3.0508","article-title":"Intradural chordoma of the tentorium cerebelli. 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