{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T21:09:41Z","timestamp":1792271381941,"version":"4.4.0"},"reference-count":8,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2022,10,8]],"date-time":"2022-10-08T00:00:00Z","timestamp":1665187200000},"content-version":"vor","delay-in-days":37,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian J Neurosurg"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Diffuse leptomeningeal glioneuronal tumor (DLGNT) is a rare tumor that was defined as a separate entity in the 2016 World Health Organization classification of brain tumors. It is most common in the pediatric age group. The diagnosis of this tumor can be made preoperatively by its characteristic imaging findings of diffuse intracranial and intraspinal nodular leptomeningeal thickening and enhancement associated with small cyst-like nonenhancing lesions in the brain and spinal cord. We report a case of DLGNT in a 7-year-old male presenting with hydrocephalus. The patient was treated successfully by cerebrospinal fluid (CSF) diversion followed by biopsy of the lesion from the cerebellum. Histopathology and immunohistochemistry confirmed the diagnosis of DLGNT. Our case would hopefully increase the awareness regarding this rare tumor and facilitate an early diagnosis and management of the affected patients with atypical radiological features.<\/jats:p>","DOI":"10.1055\/s-0042-1756637","type":"journal-article","created":{"date-parts":[[2022,10,8]],"date-time":"2022-10-08T22:32:25Z","timestamp":1665268345000},"page":"532-535","source":"Crossref","is-referenced-by-count":5,"title":["Diffuse Leptomeningeal Glioneuronal Tumor: A Rare Case Report with Review of Literature"],"prefix":"10.1055","volume":"17","author":[{"given":"Amey P.","family":"Patankar","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Baroda Medical College and SSG Hospital, Vadodara, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Palak","family":"Vaghela","sequence":"additional","affiliation":[{"name":"Department of Radiology, Sahyog Imaging Centre, Vadodara, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jitendra","family":"Nasit","sequence":"additional","affiliation":[{"name":"Department of Pathology, Baroda Medical College and SSG Hospital, Vadodara, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajvee","family":"Gohil","sequence":"additional","affiliation":[{"name":"Department of Surgery, Baroda Medical College and SSG Hospital, Vadodara, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,10,8]]},"reference":[{"issue":"02","key":"ref1","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1750-3639.2009.00285.x","article-title":"Diffuse leptomeningeal glioneuronal tumors: a new entity?","volume":"20","author":"M P Gardiman","year":"2010","journal-title":"Brain Pathol"},{"issue":"06","key":"ref2","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1007\/s00401-016-1545-1","article-title":"The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary","volume":"131","author":"D N Louis","year":"2016","journal-title":"Acta Neuropathol"},{"issue":"08","key":"ref3","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1093\/neuonc\/noab106","article-title":"The 2021 WHO Classification of Tumors of the Central Nervous System: a summary","volume":"23","author":"D N Louis","year":"2021","journal-title":"Neuro-oncol"},{"issue":"01","key":"ref4","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s00381-010-1218-7","article-title":"Spinal low-grade neoplasm with leptomeningeal dissemination mimicking tuberculous meningitis in a child","volume":"27","author":"H A Demir","year":"2011","journal-title":"Childs Nerv Syst"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.wneu.2019.12.119","article-title":"Diffuse leptomeningeal glioneuronal tumor: a unique leptomeningeal tumor entity","volume":"135","author":"S Tiwari","year":"2020","journal-title":"World Neurosurg"},{"issue":"11","key":"ref6","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.3174\/ajnr.A6737","article-title":"Diffuse leptomeningeal glioneuronal tumor of childhood","volume":"41","author":"D A Lakhani","year":"2020","journal-title":"AJNR Am J Neuroradiol"},{"issue":"06","key":"ref7","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1159\/000518802","article-title":"Spinal cord diffuse leptomeningeal glioneuronal tumor presenting without leptomeningeal dissemination","volume":"56","author":"C Perez-Vega","year":"2021","journal-title":"Pediatr Neurosurg"},{"issue":"02","key":"ref8","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/s00381-017-3584-x","article-title":"Clinical responses of patients with diffuse leptomeningeal glioneuronal tumors to chemotherapy","volume":"34","author":"D Aguilera","year":"2018","journal-title":"Childs Nerv Syst"}],"container-title":["Asian Journal of Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0042-1756637.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T01:19:27Z","timestamp":1668561567000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0042-1756637"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":8,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2022,11,15]]},"published-print":{"date-parts":[[2022,9]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0042-1756637","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1793-5482","2248-9614"],"issn-type":[{"value":"1793-5482","type":"print"},{"value":"2248-9614","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9]]}}}