{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T13:14:44Z","timestamp":1791983684617,"version":"4.4.0"},"reference-count":72,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Semin Neurol"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Headache is one of the most common diagnoses in neurology. A thorough understanding of the clinical presentation of secondary headache, which can be life-threatening, is critical. This review provides an overview of the diagnostic approach to a patient with headache, including discussion of \u201cred,\u201d \u201corange,\u201d and \u201cgreen\u201d flags. We emphasize particular scenarios to help tailor the clinical workup to individual circumstances such as in pregnant women, when particular attention must be paid to the effects of blood pressure and hypercoagulability, as well as in older adults, where there is a need for higher suspicion for an intracranial mass lesion or giant cell arteritis. Patients with risk factors for headache secondary to alterations in intracranial pressure, whether elevated (e.g., idiopathic intracranial hypertension) or decreased (e.g., cerebrospinal fluid leak), may require more specific diagnostic testing and treatment. Finally, headache in patients with COVID-19 or long COVID-19 is increasingly recognized and may have multiple etiologies.<\/jats:p>","DOI":"10.1055\/s-0042-1757753","type":"journal-article","created":{"date-parts":[[2022,10,11]],"date-time":"2022-10-11T23:11:00Z","timestamp":1665529860000},"page":"418-427","source":"Crossref","is-referenced-by-count":5,"title":["Secondary Headache Disorders: Approach, Workup, and Special Considerations for Select Populations"],"prefix":"10.1055","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7667-7905","authenticated-orcid":false,"given":"Sarah A.","family":"Friedman","sequence":"additional","affiliation":[{"name":"Department of Neurology, Weill Cornell Medicine and New York Presbyterian, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina","family":"Masters-Israilov","sequence":"additional","affiliation":[{"name":"Department of Neurology, Weill Cornell Medicine and New York Presbyterian, New 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Arida","year":"2010","journal-title":"BMC Musculoskelet Disord"},{"issue":"03","key":"ref53","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1148\/radiol.14140056","article-title":"Giant cell arteritis: diagnostic accuracy of MR imaging of superficial cranial arteries in initial diagnosis-results from a multicenter trial","volume":"273","author":"T Klink","year":"2014","journal-title":"Radiology"},{"issue":"04","key":"ref54","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/s13760-014-0290-2","article-title":"Delayed diagnosis of subacute angle closure glaucoma in patients presenting with headaches","volume":"114","author":"R Nesher","year":"2014","journal-title":"Acta Neurol Belg"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"e8557","DOI":"10.1136\/bmj.e8557","article-title":"Thunderclap headache","volume":"346","author":"A Ducros","year":"2013","journal-title":"BMJ"},{"issue":"08","key":"ref56","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1161\/STROKEAHA.112.658880","article-title":"Time-dependent test characteristics of head computed tomography in patients suspected of nontraumatic subarachnoid hemorrhage","volume":"43","author":"D Backes","year":"2012","journal-title":"Stroke"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1093\/brain\/124.2.249","article-title":"Subarachnoid haemorrhage: diagnosis, causes and management","volume":"124","author":"J van Gijn","year":"2001","journal-title":"Brain"},{"issue":"04","key":"ref58","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/head.12797","article-title":"The typical thunderclap headache of reversible cerebral vasoconstriction syndrome and its various triggers","volume":"56","author":"A 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