{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T10:21:20Z","timestamp":1783419680123,"version":"3.54.6"},"reference-count":42,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2022,12,13]],"date-time":"2022-12-13T00:00:00Z","timestamp":1670889600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Dent"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objectives\u2003This article evaluated the effect of substrates rigidities on the post-fatigue fracture resistance of adhesively cemented simplified restorations in lithium disilicate glass ceramic.<\/jats:p><jats:p>\n          Methods\u2003Precrystalized computer-aided design\/computer-aided manufacturing ceramic blocks were processed into disc-shaped specimens (n\u2009=\u200910, \u00d8\u2009=\u200910\u2009mm), mimicking a simplified restoration at two thicknesses (0.5 and 1.0\u2009mm). Thereafter, the discs were cemented onto different base substrates (dentin analogue [control], dentin analogue with a central core build-up of resin composite [RC], or glass ionomer cement [GIC]). The specimens were subjected to mechanical cycling in a chewing simulator (100\u2009N, 1\u2009\u00d7\u2009106 cycles, 4\u2009Hz) and then subjected to thermocycling aging (10,000 cycles, 5\/37\/55\u00b0C, 30\u2009seconds). After the fatigue protocol, the specimens were loaded until failure (N) in a universal testing machine. Finite element analysis calculated the first principal stress at the center of the adhesive interface.<\/jats:p><jats:p>\n          Results\u2003The results showed that \u201crestoration thickness,\u201d \u201ctype of substrate,\u201d and their interaction were statistically significant (one-way analysis of variance; p\u2009&lt;\u20090.001). Regardless the restoration thickness a higher fracture load was observed for specimens cemented to dentin analogue. Among the base materials, RC build-up presented the highest fracture load and lower stress magnitude for both restoration thicknesses in comparison with GIC build-up. The 0.5-mm restoration showed higher stress peak and lower fracture load when submitted to the compressive test.<\/jats:p><jats:p>\n          Conclusion\u2003More flexible base material reduces the fracture load and increases the stress magnitude of adhesively cemented lithium disilicate restorations regardless the ceramic thickness. Therefore, more rigid substrates are suggested to be used to prevent restoration mechanical failures.<\/jats:p>","DOI":"10.1055\/s-0042-1757910","type":"journal-article","created":{"date-parts":[[2022,12,14]],"date-time":"2022-12-14T05:48:14Z","timestamp":1670996894000},"page":"1020-1028","source":"Crossref","is-referenced-by-count":6,"title":["Substrate Rigidity Effect on CAD\/CAM Restorations at Different Thicknesses"],"prefix":"10.1055","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4830-0400","authenticated-orcid":false,"given":"C\u00e9sar Rog\u00e9rio","family":"Pucci","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry, Institute of Science and Technology, S\u00e3o Paulo State University (Unesp), S\u00e3o Jos\u00e9 dos Campos, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8123-2177","authenticated-orcid":false,"given":"Ana Paula Valente Pinho","family":"Mafetano","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry, Institute of Science and Technology, S\u00e3o Paulo State University (Unesp), S\u00e3o Jos\u00e9 dos Campos, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5707-7565","authenticated-orcid":false,"given":"Alexandre Luiz Souto","family":"Borges","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry, Institute of Science and Technology, S\u00e3o Paulo State University (Unesp), S\u00e3o Jos\u00e9 dos Campos, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5697-2947","authenticated-orcid":false,"given":"Guilherme Schmitt","family":"de Andrade","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Universidade Estadual do Oeste do Paran\u00e1 (UNIOESTE), Cascavel, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3844-2053","authenticated-orcid":false,"given":"Amanda Maria de Oliveira","family":"Dal Piva","sequence":"additional","affiliation":[{"name":"Department of Dental Materials Science, Academic Centre for Dentistry Amsterdam (ACTA), Universiteit van Amsterdam and Vrije Universiteit, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3218-8031","authenticated-orcid":false,"given":"Cornelis J.","family":"Kleverlaan","sequence":"additional","affiliation":[{"name":"Department of Dental Materials Science, Academic Centre for Dentistry Amsterdam (ACTA), Universiteit van Amsterdam and Vrije Universiteit, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5412-3546","authenticated-orcid":false,"given":"Jo\u00e3o Paulo Mendes","family":"Tribst","sequence":"additional","affiliation":[{"name":"Department of Oral Regenerative Medicine, Academic Centre for Dentistry Amsterdam (ACTA), Universiteit van Amsterdam and Vrije Universiteit, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,12,13]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.dental.2020.10.015","article-title":"Strength characterization and lifetime prediction of dental ceramic materials","volume":"37","author":"C Liu","year":"2021","journal-title":"Dent Mater"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"188","DOI":"10.34172\/joddd.2021.032","article-title":"Effect of three different veneering techniques on the stress distribution and in vitro fatigue behavior of core-veneer all-ceramic fixed partial dentures","volume":"15","author":"A LS 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