{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:08:40Z","timestamp":1787069320873,"version":"build-2736575974"},"reference-count":17,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Colon Rectal Surg"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Ileal pouch-anal anastomosis is a popular way of reconstruction the gastrointestinal tract after total proctocolectomy for ulcerative colitis. The pouch-anal anastomosis is usually stapled, which requires the preservation of a small amount of upper anal canal and lower rectum. This includes the anal transition zone (ATZ), a surprisingly small and irregular ring of tissue at and just above the dentate line. The ATZ and rectal cuff is prone to inflammation and neoplasia, particularly in patients who had a colon cancer or dysplasia at the time their large bowel was removed. This high-risk group needs ATZ\/rectal cuff surveillance before and after the surgery. Those without colorectal dysplasia preoperatively are at low risk of developing ATZ\/rectal cuff dysplasia postoperatively and follow-up can be more relaxed. Treatment of ATZ dysplasia is difficult and may mean mucosectomy, pouch advancement, pouch removal, or a redo pelvic pouch.<\/jats:p>","DOI":"10.1055\/s-0042-1758228","type":"journal-article","created":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T18:30:06Z","timestamp":1672252206000},"page":"495-498","source":"Crossref","is-referenced-by-count":7,"title":["Dysplasia at the Anal Transition Zone after IPAA"],"prefix":"10.1055","volume":"35","author":[{"given":"James","family":"Church","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Colorectal Surgery & Inflammatory Bowel Disease Center, Columbia University Medical Center, Herbert Irving Pavilion, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,12,28]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1136\/bmj.2.6130.85","article-title":"Proctocolectomy without ileostomy for ulcerative colitis","volume":"2","author":"A G Parks","year":"1978","journal-title":"BMJ"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1097\/01.sla.0000225031.15405.a3","article-title":"A comparison of hand-sewn versus stapled ileal pouch anal anastomosis (IPAA) following proctocolectomy: a meta-analysis of 4183 patients","volume":"244","author":"R E Lovegrove","year":"2006","journal-title":"Ann Surg"},{"issue":"08","key":"ref3","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1097\/DCR.0000000000001967","article-title":"Incidence and management of rectal cuff and anal transitional zone neoplasia in patients with familial adenomatous polyposis","volume":"64","author":"C HA Lee","year":"2021","journal-title":"Dis Colon Rectum"},{"key":"ref4","first-page":"1","article-title":"The anal transitional zone","volume":"289","author":"C Fenger","year":"1987","journal-title":"Acta Pathol Microbiol Immunol Scand, A, Suppl"},{"issue":"11","key":"ref5","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1046\/j.1365-2168.1998.00875.x","article-title":"A new look at the anal transitional zone with reference to restorative proctocolectomy and the columnar cuff","volume":"85","author":"M W Thompson-Fawcett","year":"1998","journal-title":"Br J Surg"},{"issue":"05","key":"ref6","first-page":"379","article-title":"The anal transitional zone. 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