{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T20:54:51Z","timestamp":1761598491410,"version":"3.37.3"},"reference-count":39,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2023,2,28]],"date-time":"2023-02-28T00:00:00Z","timestamp":1677542400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Neuropsiquiatr"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003The role of temporal lobe epilepsy (TLE) in determining personality traits and neurobehavioral symptoms, collectively known as the interictal behavioral syndrome (also known as Geschwind syndrome or \u201cGastaut-Geschwind syndrome\u201d), as well as the syndrome's association with the particular artistic expression of many epileptic litterateurs are well known in neurology and psychiatry. A deepening of emotionality along with a serious, highly ethical, and spiritual behavior have been described as positive personality changes among patients with chronic mesial-TLE.<\/jats:p><jats:p>\n          Objectives\u2003Our narrative-based clinical hypothesis aims at contributing to the ongoing debate on the association between TLE and artistic expression, as well as the latter's supposed implication for epileptology in general and the neuropsychology of epilepsy in particular.<\/jats:p><jats:p>\n          Methods\u2003Through an analysis of the biography, language, and literary work of Greek novelist Demosthenes Voutyras, we hypothesize that his mystical and dark writing style could be attributed to medial temporal interictal dynamics.<\/jats:p><jats:p>\n          Conclusions\u2003We suggest that the psycholiterary profile of Voutyras is consistent with the idiosyncratic characteristics of the temporal lobe personality, while a non-dominant temporal lobe contribution has been proposed.<\/jats:p>","DOI":"10.1055\/s-0042-1758443","type":"journal-article","created":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:18:22Z","timestamp":1677629902000},"page":"384-391","source":"Crossref","is-referenced-by-count":1,"title":["Epilepsy and the \u201cdark\u201d literature of the Greek novelist Demosthenes Voutyras: an outstanding epileptic personality"],"prefix":"10.1055","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4474-7566","authenticated-orcid":false,"given":"Panayiotis","family":"Patrikelis","sequence":"additional","affiliation":[{"name":"National and Kapodistrian University of Athens, School of Medicine, Evangelismos Hospital, First Department of Neurosurgery, Athens, Greece."},{"name":"Aristotle University of Thessaloniki, Faculty of Philosophy, School of Psychology, Thessaloniki, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3216-9025","authenticated-orcid":false,"given":"Lambros","family":"Messinis","sequence":"additional","affiliation":[{"name":"Aristotle University of Thessaloniki, Faculty of Philosophy, School of Psychology, Thessaloniki, Greece."},{"name":"University Hospital of Patras, School of Medicine, Departments of Neurology and Psychiatry, Patras, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2159-7032","authenticated-orcid":false,"given":"Vasiliki","family":"Folia","sequence":"additional","affiliation":[{"name":"Aristotle University of Thessaloniki, Faculty of Philosophy, School of Psychology, Thessaloniki, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7495-6863","authenticated-orcid":false,"given":"Grigorios","family":"Nasios","sequence":"additional","affiliation":[{"name":"University of Ioannina, School of Health Sciences, Department of Speech and Language Therapy, Ioannina, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8137-8253","authenticated-orcid":false,"given":"Athanasia","family":"Alexoudi","sequence":"additional","affiliation":[{"name":"National and Kapodistrian University of Athens, School of Medicine, Evangelismos Hospital, First Department of Neurosurgery, Athens, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5649-2564","authenticated-orcid":false,"given":"Anastasia","family":"Verentzioti","sequence":"additional","affiliation":[{"name":"National and Kapodistrian University of Athens, School of Medicine, Evangelismos Hospital, First Department of Neurosurgery, Athens, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9262-2031","authenticated-orcid":false,"given":"Stefanos","family":"Korfias","sequence":"additional","affiliation":[{"name":"National and Kapodistrian University of Athens, School of Medicine, Evangelismos Hospital, First Department of Neurosurgery, Athens, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3335-3019","authenticated-orcid":false,"given":"Vasileios","family":"Kimiskidis","sequence":"additional","affiliation":[{"name":"Aristotle University of Thessaloniki, Faculty of Health Sciences, School of Medicine, 1st Department of Neurology, Thessaloniki, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6498-3929","authenticated-orcid":false,"given":"Stylianos","family":"Gatzonis","sequence":"additional","affiliation":[{"name":"National and Kapodistrian University of Athens, School of Medicine, Evangelismos Hospital, First Department of Neurosurgery, Athens, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,2,28]]},"reference":[{"volume-title":"History of Modern Greek Literature","year":"2008","author":"M Vitti","key":"ref1"},{"volume-title":"A history of Modern Greek literature","year":"1973","author":"L Polit\u0113s","key":"ref4"},{"issue":"08","key":"ref6","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1001\/archneur.1977.00500200014003","article-title":"Quantitative analysis of interictal behavior in temporal lobe epilepsy","volume":"34","author":"D M Bear","year":"1977","journal-title":"Arch 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No end to retrospective diagnostics","volume":"13","author":"A Karenberg","year":"2004","journal-title":"J Hist Neurosci"},{"key":"ref29","first-page":"783","volume-title":"The history of the doctor-patient relationship. Companion Encyclopedia of the History of Medicine","author":"E Shorter","year":"1997"},{"key":"ref30","first-page":"801","volume-title":"The art of diagnosis: medicine and the five senses. 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