{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T21:37:46Z","timestamp":1783201066206,"version":"3.54.6"},"reference-count":34,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2022,12,11]],"date-time":"2022-12-11T00:00:00Z","timestamp":1670716800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Plast Surg"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Introduction\u2003Hidradenitis suppurativa (HS) is a chronic, debilitating, recurrent, auto-inflammatory disease of the pilosebaceous units of the skin. The axillary region is the most affected anatomical site and its reconstructive options include skin grafts, local random plasties, regional axial flaps, and regional perforator flaps. The main aim of this systematic review is to identify the best surgical technique for axillary reconstruction in the context of HS, in terms of efficacy and safety.<\/jats:p><jats:p>\n          Methods\u2003We adhered to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) throughout the whole review protocol build-up. The literature search was performed using MEDLINE, Embase, and Cochrane library databases, updated to March 2021. Quality was assessed for each study, through the National Institutes of Health Quality Assessment Tool.<\/jats:p><jats:p>\n          Results\u2003A total of 23 studies were included in the final analysis. We reviewed a total of 394 axillary reconstructions in 313 patients affected by HS Hurley Stage II or III. Skin grafts were associated with the highest overall complication rate (37%), and highest rate of reconstruction failure (22%). Between thoraco-dorsal artery perforator flap, posterior arm flap, and parascapular flap, the latter showed fewer total complications, recurrences, and failures.<\/jats:p><jats:p>\n          Conclusion\u2003Regional axial flaps should be considered as the best surgical approach in the management of advanced HS. The parascapular flap emerges as the most effective and safest option for axillary reconstruction. Local random flaps might be considered only for selected minor excisions, due to the higher risk of recurrence. The use of skin grafts for axillary reconstruction is discouraged.<\/jats:p>","DOI":"10.1055\/s-0042-1758452","type":"journal-article","created":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T14:04:47Z","timestamp":1670853887000},"page":"006-012","source":"Crossref","is-referenced-by-count":10,"title":["Reconstruction of the Axillary Region after Excision of Hidradenitis Suppurativa: A Systematic Review"],"prefix":"10.1055","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1410-7568","authenticated-orcid":false,"given":"Francesco","family":"Amendola","sequence":"additional","affiliation":[{"name":"Department of Reconstructive and Aesthetic Plastic Surgery, University of Milan, I.R.C.C.S. Istituto Ortopedico Galeazzi, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Cottone","sequence":"additional","affiliation":[{"name":"Department of Reconstructive and Aesthetic Plastic Surgery, University of Milan, I.R.C.C.S. Istituto Ortopedico Galeazzi, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5506-8323","authenticated-orcid":false,"given":"Mario","family":"Alessandri-Bonetti","sequence":"additional","affiliation":[{"name":"Department of Reconstructive and Aesthetic Plastic Surgery, University of Milan, I.R.C.C.S. Istituto Ortopedico Galeazzi, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4759-2758","authenticated-orcid":false,"given":"Francesco","family":"Borelli","sequence":"additional","affiliation":[{"name":"Department of Reconstructive and Aesthetic Plastic Surgery, University of Milan, I.R.C.C.S. Istituto Ortopedico Galeazzi, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Catapano","sequence":"additional","affiliation":[{"name":"Department of Reconstructive and Aesthetic Plastic Surgery, University of Milan, I.R.C.C.S. Istituto Ortopedico Galeazzi, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Carbonaro","sequence":"additional","affiliation":[{"name":"Department of Reconstructive and Aesthetic Plastic Surgery, University of Milan, I.R.C.C.S. Istituto Ortopedico Galeazzi, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Riccardi","sequence":"additional","affiliation":[{"name":"Department of Reconstructive and Aesthetic Plastic Surgery, University of Milan, I.R.C.C.S. Istituto Ortopedico Galeazzi, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Vaienti","sequence":"additional","affiliation":[{"name":"Department of Reconstructive and Aesthetic Plastic Surgery, University of Milan, I.R.C.C.S. Istituto Ortopedico Galeazzi, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,12,11]]},"reference":[{"issue":"05","key":"ref1","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/S0007-1226(03)00177-2","article-title":"Hidradenitis suppurativa: pathogenesis and management","volume":"56","author":"D E Slade","year":"2003","journal-title":"Br J Plast Surg"},{"issue":"04","key":"ref2","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.jaad.2008.11.911","article-title":"Hidradenitis suppurativa: a comprehensive review","volume":"60","author":"A Alikhan","year":"2009","journal-title":"J Am Acad Dermatol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"F1000","DOI":"10.12688\/f1000research.26083.1","article-title":"The most recent advances in understanding and managing hidradenitis suppurativa","volume":"9","author":"S Narla","year":"2020","journal-title":"F1000 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Alharbi","year":"2012","journal-title":"BMC Dermatol"},{"issue":"11","key":"ref32","doi-asserted-by":"crossref","first-page":"e440","DOI":"10.1111\/ijd.15293","article-title":"Trends in the management of hidradenitis suppurativa in the Middle East region: a systematic review","volume":"60","author":"M Karvar","year":"2021","journal-title":"Int J Dermatol"},{"issue":"01","key":"ref33","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1097\/DSS.0000000000000942","article-title":"Patient satisfaction and quality of life following surgery for hidradenitis suppurativa","volume":"43","author":"J J Kohorst","year":"2017","journal-title":"Dermatol Surg"},{"issue":"06","key":"ref34","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1046\/j.1365-2133.1999.03224.x","article-title":"Finasteride as a therapy for hidradenitis suppurativa","volume":"141","author":"A M Farrell","year":"1999","journal-title":"Br J 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Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0042-1758452.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,28]],"date-time":"2023-03-28T23:49:13Z","timestamp":1680047353000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0042-1758452"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,11]]},"references-count":34,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2023,3,28]]},"published-print":{"date-parts":[[2023,2]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0042-1758452","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0970-0358","1998-376X"],"issn-type":[{"value":"0970-0358","type":"print"},{"value":"1998-376X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,11]]}}}