{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T18:08:07Z","timestamp":1779300487104,"version":"3.51.4"},"reference-count":32,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Semin Plast Surg"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Despite being relatively uncommon in the general population, thumb amputations cause severe disability. More than 3,300 thumb amputations occurred in the United States. The thumb makes up around 40% of the function of the hand. Therefore, losing it would result in significant medical, hospital, and societal costs. Thumb reconstruction surgery's primary goal is to restore grip strength, including the range of motion, fine and tripod pinch, power grasp, strength, and sensibility, while secondary goals include restoring hand aesthetics. In cases of thumb replantation, like-for-like replacement is possible; however, when thumb replantation is not possible, great toe-to-hand transplantation is the best available reconstruction. When compared with other reconstructive options such as osteoplastic thumb reconstruction, pollicization, second toe transplantation, and the use of a thumb prosthesis, great toe transplantation provides superior function and aesthetics. For restoring pinch, sensitivity, strength, and aesthetics of the hand with well-tolerated donor site morbidity, toe to thumb transplantation is regarded as the gold standard.<\/jats:p>","DOI":"10.1055\/s-0042-1758689","type":"journal-article","created":{"date-parts":[[2022,11,22]],"date-time":"2022-11-22T00:25:57Z","timestamp":1669076757000},"page":"243-252","source":"Crossref","is-referenced-by-count":9,"title":["Great Toe Transplantation"],"prefix":"10.1055","volume":"36","author":[{"given":"Antonio J.","family":"Forte","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Mayo Clinic, Jacksonville, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karla C.","family":"Maita","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Mayo Clinic, Jacksonville, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo A.","family":"Torres-Guzman","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Mayo Clinic, Jacksonville, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco R.","family":"Avila","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Mayo Clinic, Jacksonville, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bauback","family":"Safa","sequence":"additional","affiliation":[{"name":"The Buncke Medical Clinic, San Francisco, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory","family":"Buncke","sequence":"additional","affiliation":[{"name":"The Buncke Medical Clinic, San Francisco, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rudolph","family":"Buntic","sequence":"additional","affiliation":[{"name":"The Buncke Medical Clinic, San Francisco, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Watt","sequence":"additional","affiliation":[{"name":"The Buncke Medical Clinic, San Francisco, California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,11,21]]},"reference":[{"issue":"S 01","key":"ref1","doi-asserted-by":"crossref","first-page":"i115","DOI":"10.1136\/injuryprev-2019-043495","article-title":"Global trends of hand and wrist trauma: a systematic analysis of fracture and digit amputation using the Global Burden of Disease 2017 Study","volume":"26","author":"C S Crowe","year":"2020","journal-title":"Inj Prev"},{"issue":"06","key":"ref2","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1097\/SAP.0b013e31828986c9","article-title":"A nationwide review of the treatment patterns of traumatic thumb amputations","volume":"70","author":"C M Shale","year":"2013","journal-title":"Ann Plast Surg"},{"issue":"04","key":"ref3","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1007\/BF01675645","article-title":"To trim or replant: a matter of cost","volume":"15","author":"J Engel","year":"1991","journal-title":"World J Surg"},{"issue":"04","key":"ref4","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1097\/PRS.0000000000000019","article-title":"Economic analysis of revision amputation and replantation treatment of finger amputation injuries","volume":"133","author":"E D Sears","year":"2014","journal-title":"Plast Reconstr Surg"},{"issue":"12","key":"ref5","doi-asserted-by":"crossref","first-page":"2614","DOI":"10.1016\/j.injury.2016.09.041","article-title":"Direct, indirect and intangible costs of acute hand and wrist injuries: a systematic review","volume":"47","author":"L S Robinson","year":"2016","journal-title":"Injury"},{"issue":"02","key":"ref6","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1097\/00000637-199602000-00014","article-title":"Anatomy, physiology, and functional restoration of the thumb","volume":"36","author":"E T Emerson","year":"1996","journal-title":"Ann Plast Surg"},{"issue":"04","key":"ref7","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.cps.2011.07.001","article-title":"Toe-to-hand transplantation","volume":"38","author":"W L Lam","year":"2011","journal-title":"Clin Plast Surg"},{"issue":"03","key":"ref8","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1097\/01.prs.0000200627.74575.15","article-title":"Pollicization of the index finger for traumatic thumb amputation","volume":"117","author":"O Ishida","year":"2006","journal-title":"Plast Reconstr Surg"},{"issue":"04","key":"ref9","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1302\/0301-620X.51B4.677","article-title":"Free digital transfer. 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