{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T04:32:57Z","timestamp":1773808377374,"version":"3.50.1"},"reference-count":22,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T00:00:00Z","timestamp":1670371200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Radiol Imaging"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Aim\u2003To determine the diagnostic effectiveness of third-trimester fetal Doppler studies in pregnancy for stillbirths and neonatal mortality in the Samrakshan program of the Indian Radiological and Imaging Association (IRIA).<\/jats:p><jats:p>\n          Methods\u2003The mean uterine artery (UtA) pulsatility index (PI)\u2009&gt;\u200995th percentile, umbilical artery PI\u2009&gt;\u200995th percentile, middle cerebral artery (MCA) PI\u2009&lt;\u20095th percentile, and\/or cerebroplacental ratio (CPR)\u2009&lt;\u20095th percentile in the third trimester fetal Doppler study was considered as abnormal. The results of the fetal Doppler study closest to childbirth were considered for analysis. Late stillbirth (SB) was defined as a fetal loss between 28 and 36 gestation weeks and the term SB was defined as a fetal loss at \u2265 37 gestation weeks. Neonatal death was defined as the demise of a live-born baby within the first 28 days of life. Parameters of diagnostic effectiveness such as sensitivity, specificity, positive and negative predictive values and likelihood ratios, diagnostic odds ratio, and the area under receiver operator characteristic (AUROC) curve were assessed.<\/jats:p><jats:p>\n          Results\u2003Screening of 1,326 pregnant women in the third trimester of pregnancy between September 2019 and February 2022, identified 308 (23.23%) abnormal Doppler studies, 11 (0.83%) SB, and 11 (0.84%) neonatal deaths. An abnormal Doppler study was significantly associated with late stillbirths (OR 37.2, 95% CI: 2.05, 674) but not with term SB (OR: 3.38, 95% CI: 0.76, 15) or neonatal deaths (OR 1.39, 95% CI: 0.40, 4.87). Mean UtA PI, umbilical artery PI, MCA PI, and CPR were significantly associated with late SB and not term SB. The AUROC of Doppler measures was excellent for late SB but did not show discriminatory ability for term SB or neonatal deaths.<\/jats:p><jats:p>\n          Conclusion\u2003Integration of fetal Doppler with routine third-trimester antenatal scans can help identify pregnant women at high risk for late SB. The effectiveness of fetal Doppler to identify pregnant women at high risk for term SB and neonatal deaths needs further study on a larger sample size.<\/jats:p>","DOI":"10.1055\/s-0042-1759637","type":"journal-article","created":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T00:07:01Z","timestamp":1670458021000},"page":"028-035","source":"Crossref","is-referenced-by-count":4,"title":["Diagnostic Effectiveness of Third-Trimester Fetal Doppler Studies in Pregnancy to Predict Late-and-Term Stillbirth and Neonatal Mortality in the Samrakshan Program in India"],"prefix":"10.1055","volume":"33","author":[{"given":"Rijo Mathew","family":"Choorakuttil","sequence":"additional","affiliation":[{"name":"Department of Clinical Radiology, AMMA Center for Diagnosis and Preventive Medicine, Kochi, Kerala, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shilpa R.","family":"Satarkar","sequence":"additional","affiliation":[{"name":"Department of Clinical Radiology, Antarang Sonography and Colour Doppler Center, Satarkar Hospital, Aurangabad, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lalit K.","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Clinical Radiology, Raj Sonography & X-Ray Clinic, Baiju Choraha, Nayapura, Guna, Madhya Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anjali","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Clinical Radiology, Anjali Ultrasound and Colour Doppler Centre, Agra, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akanksha","family":"Baghel","sequence":"additional","affiliation":[{"name":"Department of Clinical Radiology, Baghel Sonography Center, Harda, Madhya Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eesha","family":"Rajput","sequence":"additional","affiliation":[{"name":"Department of Radiology, INHS Asvini, 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