{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T16:17:52Z","timestamp":1740154672153,"version":"3.37.3"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2022,12,16]],"date-time":"2022-12-16T00:00:00Z","timestamp":1671148800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Radiol Imaging"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Purpose\u2003Our aim was to assess the sinonasal magnetic resonance imaging (MRI) features of acute invasive fungal rhinosinusitis (AIFRS) in coronavirus disease (COVID)-associated mucormycosis (CAM) and to correlate these with histopathology and patient outcome in terms of duration of hospital stay and survival at 10 weeks.<\/jats:p><jats:p>\n          Methods\u2003Twenty patients with histopathologically confirmed sinonasal CAM underwent MRI (including postcontrast T1-weighted and diffusion-weighted imaging). Histopathological findings (presence of coagulative necrosis, granulomatous reaction, and fungal burden) were recorded and all patients were followed up at 6 and 10 weeks. Statistical analysis was done using chi-square test and Fischer's exact test.<\/jats:p><jats:p>\n          Results\u2003Enhancement patterns seen in our subjects included homogeneous, heterogeneous, and lack of contrast enhancement (LOC), with LOC being the most common (65%). Diffusion restriction was found in 90% patients. Statistically significant correlation was found between LOC pattern and presence of coagulative necrosis (p-value\u2009=\u20090.007), extent of fungal hyphae (p-value\u2009=\u20090.047), and duration of hospital stay (p-value\u2009=\u20090.004). Restricted diffusion was also seen to correlate with a high fungal load (p-value\u2009=\u20090.007).<\/jats:p><jats:p>\n          Conclusion\u2003Our study describes the MRI findings of AIFRS in CAM and highlights the imaging features which may be surrogate markers for coagulative necrosis and fungal burden.<\/jats:p>","DOI":"10.1055\/s-0042-1759639","type":"journal-article","created":{"date-parts":[[2022,12,17]],"date-time":"2022-12-17T00:32:36Z","timestamp":1671237156000},"page":"046-052","source":"Crossref","is-referenced-by-count":2,"title":["COVID-Associated Sinonasal Mucormycosis: Radiological Pathological Correlation and Prognostic Value of MR Imaging"],"prefix":"10.1055","volume":"33","author":[{"given":"Sheetal","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Lok Nayak Hospital and Maulana Azad Medical College, New Delhi, 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