{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T21:03:19Z","timestamp":1774040599404,"version":"3.50.1"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"07","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fortschr R\u00f6ntgenstr"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:p>\n            Purpose\u2002Recent studies have suggested that intraluminal thrombi show contrast enhancement on carotid black-blood T1w MRI. The aim of this study was to evaluate the significance of intraluminal contrast enhancement (iCE) regarding symptom status in patients with spontaneous cervical artery dissection (sCAD).<\/jats:p><jats:p>\n            Methods\u200233 consecutive patients (19 men) with sCAD\u200areceived a brain MRI (DIFF, T2w, T2*w, FLAIR) and a multi-sequence 3T-MRI with fat-saturated high-resolution black-blood T1w-sequences pre- and post-contrast, contrast-enhanced MR angiography and TOF images of carotid and vertebral arteries. Presence\/absence of iCE, vessel occlusion and vessel wall hematoma (hyperintense in T1w pre-contrast) were analysed by two radiologists in consensus decision.<\/jats:p><jats:p>\n            Results\u200244 of 132 analysed vessels had a vessel wall hematoma, consistent with sCAD. In 17 of 44 dissected vessels an acute ischemic stroke was found. 16 of 17 (94.1\u200a%) vessels ipsilateral to ischemic stroke demonstrated iCE, compared to 9 of 44 (20.4\u200a%) dissected vessels without stroke (P&lt;\u200a0.001). The presence\/absence of iCE resulted in\u00a0a sensitivity, specificity, positive and negative predictive value and accuracy for ischemic stroke of 0.94, 0.67, 0.64, 0.95, and 0.77, respectively, and an odds ratio of 32.0.<\/jats:p><jats:p>\n            Conclusion\u2002iCE, which is suggestive of intraluminal thrombus formation, is strongly correlated with ischemic symptoms in patients with sCAD.<\/jats:p><jats:p>\n            Key points\u2002<\/jats:p><jats:p>\n            Citation Format\n          <\/jats:p>","DOI":"10.1055\/s-0043-104632","type":"journal-article","created":{"date-parts":[[2017,4,26]],"date-time":"2017-04-26T22:53:42Z","timestamp":1493247222000},"page":"624-631","source":"Crossref","is-referenced-by-count":28,"title":["Clinical Significance of Intraluminal Contrast Enhancement in Patients with Spontaneous Cervical Artery Dissection: A\u00a0Black-Blood MRI Study"],"prefix":"10.1055","volume":"189","author":[{"given":"Eva","family":"Coppenrath","sequence":"additional","affiliation":[{"name":"Institute of Clinical Radiology, Ludwig-Maximilians-University Munich, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga","family":"Lenz","sequence":"additional","affiliation":[{"name":"Institute of Clinical Radiology, Ludwig-Maximilians-University Munich, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nora","family":"Sommer","sequence":"additional","affiliation":[{"name":"Institute of Clinical Radiology, Ludwig-Maximilians-University Munich, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina","family":"Lummel","sequence":"additional","affiliation":[{"name":"Institute of Neuroradiology and Interventional Neuroradiology, University Hospital Klinikum rechts der Isar Munich, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Linn","sequence":"additional","affiliation":[{"name":"Institute of Neuroradiology, University Hospital Carl Gustav Carus, Dresden, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karla","family":"Treitl","sequence":"additional","affiliation":[{"name":"Institute of Clinical Radiology, Ludwig-Maximilians-University Munich, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabian","family":"Bamberg","sequence":"additional","affiliation":[{"name":"Diagnostical and Interventional Radiology, Eberhard Karls University Tuebingen, Tuebingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maximilian","family":"Reiser","sequence":"additional","affiliation":[{"name":"Institute of Clinical Radiology, Ludwig-Maximilians-University Munich, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Pfefferkorn","sequence":"additional","affiliation":[{"name":"Interdisciplinary Stroke Center Munich, Ludwig-Maximilians-University Munich, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobias","family":"Saam","sequence":"additional","affiliation":[{"name":"Radiology Center Rosenheim, Rosenheim, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2017,4,26]]},"container-title":["R\u00f6Fo - Fortschritte auf dem Gebiet der R\u00f6ntgenstrahlen und der bildgebenden Verfahren"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0043-104632.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,12,19]],"date-time":"2017-12-19T07:32:50Z","timestamp":1513668770000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0043-104632"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,26]]},"references-count":0,"journal-issue":{"issue":"07","published-online":{"date-parts":[[2017,6,26]]},"published-print":{"date-parts":[[2017,7]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0043-104632","relation":{},"ISSN":["1438-9029","1438-9010"],"issn-type":[{"value":"1438-9029","type":"print"},{"value":"1438-9010","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,26]]}}}