{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T20:36:46Z","timestamp":1792701406354,"version":"4.5.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"07","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endoscopy"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>MAIN RECOMMENDATIONS<\/jats:title>\n                  <jats:p>For pancreatic solid lesions, ESGE recommends performing endoscopic ultrasound (EUS)-guided sampling as first-line procedure when a pathological diagnosis is required. Alternatively, percutaneous sampling may be considered in metastatic disease.<\/jats:p>\n                  <jats:p>Strong recommendation, moderate quality evidence.<\/jats:p>\n                  <jats:p>In the case of negative or inconclusive results and a high degree of suspicion of malignant disease, ESGE suggests re-evaluating the pathology slides, repeating EUS-guided sampling, or surgery.<\/jats:p>\n                  <jats:p>Weak recommendation, low quality evidence.<\/jats:p>\n                  <jats:p>In patients with chronic pancreatitis associated with a pancreatic mass, EUS-guided sampling results that do not confirm cancer should be interpreted with caution.<\/jats:p>\n                  <jats:p>Strong recommendation, low quality evidence.<\/jats:p>\n                  <jats:p>For pancreatic cystic lesions (PCLs), ESGE recommends EUS-guided sampling for biochemical analyses plus cytopathological examination if a precise diagnosis may change patient management, except for lesions\u200a\u2264\u200a10\u200amm in diameter with no high risk stigmata. If the volume of PCL aspirate is small, it is recommended that carcinoembryonic antigen (CEA) level determination be done as the first analysis.<\/jats:p>\n                  <jats:p>Strong recommendation, low quality evidence.<\/jats:p>\n                  <jats:p>For esophageal cancer, ESGE suggests performing EUS-guided sampling for the assessment of regional lymph nodes (LNs) in T1 (and, depending on local treatment policy, T2) adenocarcinoma and of lesions suspicious for metastasis such as distant LNs, left liver lobe lesions, and suspected peritoneal carcinomatosis.<\/jats:p>\n                  <jats:p>Weak recommendation, low quality evidence.<\/jats:p>\n                  <jats:p>For lymphadenopathy of unknown origin, ESGE recommends performing EUS-guided (or alternatively endobronchial ultrasound [EBUS]-guided) sampling if the pathological result is likely to affect patient management and no superficial lymphadenopathy is easily accessible.<\/jats:p>\n                  <jats:p>Strong recommendation, moderate quality evidence.<\/jats:p>\n                  <jats:p>In the case of solid liver masses suspicious for metastasis, ESGE suggests performing EUS-guided sampling if the pathological result is likely to affect patient management, and (i) the lesion is poorly accessible\/not detected at percutaneous imaging, or (ii) a sample obtained via the percutaneous route repeatedly yielded an inconclusive result.<\/jats:p>\n                  <jats:p>Weak recommendation, low quality evidence.<\/jats:p>","DOI":"10.1055\/s-0043-109021","type":"journal-article","created":{"date-parts":[[2017,5,16]],"date-time":"2017-05-16T18:56:44Z","timestamp":1494961004000},"page":"695-714","source":"Crossref","is-referenced-by-count":298,"title":["Indications, results, and clinical impact of endoscopic ultrasound (EUS)-guided sampling in gastroenterology: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline \u2013 Updated January 2017"],"prefix":"10.1055","volume":"49","author":[{"given":"Jean-Marc","family":"Dumonceau","sequence":"additional","affiliation":[{"name":"Gedyt Endoscopy Center, Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Deprez","sequence":"additional","affiliation":[{"name":"Cliniques universitaires St-Luc, Universit\u00e9 Catholique de Louvain, Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Jenssen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Krankenhaus M\u00e4rkisch Oderland Strauberg\/Wriezen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julio","family":"Iglesias-Garcia","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, University Hospital of Santiago de Compostela, Santiago de Compostela, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Larghi","sequence":"additional","affiliation":[{"name":"Digestive Endoscopy Unit, Catholic University, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffroy","family":"Vanbiervliet","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Endoscopy, H\u00f4pital Universitaire l\u2019Archet, Nice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guruprasad","family":"Aithal","sequence":"additional","affiliation":[{"name":"Nottingham Digestive Diseases Centre, NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Arcidiacono","sequence":"additional","affiliation":[{"name":"Pancreato-Biliary Endoscopy and Endosonography Division, San Raffaele University, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Bastos","sequence":"additional","affiliation":[{"name":"Gastroenterology Department Instituto Portugu\u00eas de Oncologia do Porto, Porto, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Carrara","sequence":"additional","affiliation":[{"name":"Digestive Endoscopy Unit, Division of Gastroenterology, Humanitas Research Hospital, Rozzano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e1szl\u00f3","family":"Czak\u00f3","sequence":"additional","affiliation":[{"name":"First Department of Medicine, University of Szeged, Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria","family":"Fern\u00e1ndez-Esparrach","sequence":"additional","affiliation":[{"name":"Endoscopy Unit, Department of Gastroenterology, ICMDM, IDIBAPS, CIBEREHD, Hospital Cl\u00ednic, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Fockens","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c0ngels","family":"Gin\u00e8s","sequence":"additional","affiliation":[{"name":"Endoscopy Unit, Department of Gastroenterology, ICMDM, IDIBAPS, CIBEREHD, Hospital Cl\u00ednic, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roald","family":"Havre","sequence":"additional","affiliation":[{"name":"National Centre for Ultrasound in Gastroenterology, Haukeland University Hospital, Bergen and Department of Clinical Medicine, University of Bergen, Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesare","family":"Hassan","sequence":"additional","affiliation":[{"name":"Digestive Endoscopy Unit, Catholic University, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Vilmann","sequence":"additional","affiliation":[{"name":"Department of Surgical Gastroenterology, Herlev Hospital and Gentofte, Hospital, Copenhagen University, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanin","family":"van Hooft","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcin","family":"Polkowski","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Medical Centre for Postgraduate Education and Department of Gastroenterology, M. Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2017,5,16]]},"container-title":["Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0043-109021.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,12,19]],"date-time":"2017-12-19T02:35:53Z","timestamp":1513650953000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0043-109021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,16]]},"references-count":0,"journal-issue":{"issue":"07","published-online":{"date-parts":[[2017,6,28]]},"published-print":{"date-parts":[[2017,7]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0043-109021","relation":{},"ISSN":["0013-726X","1438-8812"],"issn-type":[{"value":"0013-726X","type":"print"},{"value":"1438-8812","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,16]]}}}