{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,27]],"date-time":"2024-07-27T02:18:40Z","timestamp":1722046720916},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"07","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Clin Endocrinol Diabetes"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\nBackground Vitamin D deficiency represents a global health problem, affecting children and adolescents worldwide.<\/jats:p><jats:p>\nObjects To confirm that vitamin D deficiency can present as a spectrum of clinical pictures.<\/jats:p><jats:p>\nMethods We diagnosed nutritional rickets in a 10-month-old infant of Senegal origin with several risk factors for vitamin D deficiency. As many of these factors affected also his cohabitant relatives, we evaluate infant\u2019s family members (mother and 4 brothers) looking for other vitamin D deficiency-related comorbidities.<\/jats:p><jats:p>\nResults 3 brothers had asymptomatic vitamin D deficiency and 2 of them (9.8 and 13.4 years-old) showed secondary hyperparathyroidism. The fourth brother (11.3 years-old) had nutritional rickets. Their mother was affected by osteomalacia. None of them received vitamin D supplementation.<\/jats:p><jats:p>\nConclusion Vitamin D deficiency may present as a spectrum of clinical pictures, representing a continuum ranging from asymptomatic\/subtle conditions to overt rickets\/osteomalacia. Immigrant families are at high risk for vitamin D deficiency at every age. If a case of symptomatic vitamin D deficiency is recognized, then the evaluation of the all family members is recommended, as they can have the same and\/or other risk factors for vitamin D deficiency.<\/jats:p>","DOI":"10.1055\/s-0043-109699","type":"journal-article","created":{"date-parts":[[2017,7,19]],"date-time":"2017-07-19T22:34:34Z","timestamp":1500503674000},"page":"478-484","source":"Crossref","is-referenced-by-count":3,"title":["The Spectrum of Vitamin D Deficiency: Description of a Family"],"prefix":"10.1055","volume":"125","author":[{"given":"Francesco","family":"Vierucci","sequence":"additional","affiliation":[{"name":"S.C. Pediatria, Ospedale San Luca, Lucca, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Del Pistoia","sequence":"additional","affiliation":[{"name":"U.O. Pediatria Universitaria, Dipartimento Materno Infantile, Azienda Ospedaliero-Universitaria Pisana, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emioli","family":"Randazzo","sequence":"additional","affiliation":[{"name":"U.O. Pediatria Universitaria, Dipartimento Materno Infantile, Azienda Ospedaliero-Universitaria Pisana, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Massart","sequence":"additional","affiliation":[{"name":"U.O. Pediatria Universitaria, Dipartimento Materno Infantile, Azienda Ospedaliero-Universitaria Pisana, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Federico","sequence":"additional","affiliation":[{"name":"U.O. Pediatria Universitaria, Dipartimento Materno Infantile, Azienda Ospedaliero-Universitaria Pisana, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2017,7,19]]},"container-title":["Experimental and Clinical Endocrinology &amp; Diabetes"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0043-109699.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,12,19]],"date-time":"2017-12-19T08:32:37Z","timestamp":1513672357000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0043-109699"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":0,"journal-issue":{"issue":"07","published-online":{"date-parts":[[2017,7,19]]},"published-print":{"date-parts":[[2017,7]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0043-109699","relation":{},"ISSN":["0947-7349","1439-3646"],"issn-type":[{"value":"0947-7349","type":"print"},{"value":"1439-3646","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7]]}}}