{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T23:28:19Z","timestamp":1788910099027,"version":"build-2803163510"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacopsychiatry"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\nIntroduction Despite empirical evidence for the efficacy of body-oriented yoga as add-on treatment for major depressive disorder (MDD), the specific mechanisms by which yoga leads to therapeutic changes remain unclear. By means of a systematic review, we evaluate how the field is progressing in its empirical investigation of mechanisms of change in yoga for MDD.<\/jats:p><jats:p>\nMethods To identify relevant studies, a systematic search was conducted.<\/jats:p><jats:p>\nResults The search produced 441 articles, of which 5 were included, that empirically examined 2 psychological mechanisms (mindfulness, rumination) and 3 biological mechanisms (vagal control, heart rate variability [HRV], brain-derived neurotrophic factor [BDNF], cortisol). 2 studies found that decreased rumination and 1 study that increased mindfulness was associated with the effect of yoga on treatment outcome. In addition, preliminary studies suggest that alterations in cortisol, BDNF, and HRV may play a role in how yoga exerts its clinical effect.<\/jats:p><jats:p>\nDiscussion The results suggest that body-oriented yoga could work through some of the theoretically predicted mechanisms. However, there is a need for more rigorous designs that can assess greater levels of causal specificity.<\/jats:p>","DOI":"10.1055\/s-0043-111013","type":"journal-article","created":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T23:16:15Z","timestamp":1496358975000},"page":"73-81","source":"Crossref","is-referenced-by-count":26,"title":["A Systematic Review of Mechanisms of Change in Body-Oriented Yoga in Major Depressive Disorders"],"prefix":"10.1055","volume":"51","author":[{"given":"Klara","family":"Meister","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Psychotherapy and Preventive Medicine Ruhr University Bochum, LWL University Hospital, Bochum, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Juckel","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Psychotherapy and Preventive Medicine Ruhr University Bochum, LWL University Hospital, Bochum, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2017,6,1]]},"container-title":["Pharmacopsychiatry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0043-111013.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,5,9]],"date-time":"2018-05-09T22:41:42Z","timestamp":1525905702000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0043-111013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,1]]},"references-count":0,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2018,5,9]]},"published-print":{"date-parts":[[2018,5]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0043-111013","relation":{},"ISSN":["0176-3679","1439-0795"],"issn-type":[{"value":"0176-3679","type":"print"},{"value":"1439-0795","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,1]]}}}