{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T07:12:48Z","timestamp":1792653168211,"version":"4.5.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"07","license":[{"start":{"date-parts":[[2017,7,6]],"date-time":"2017-07-06T00:00:00Z","timestamp":1499299200000},"content-version":"vor","delay-in-days":5,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background and study aims\u2002Peroral endoscopic myotomy (POEM) is an evolving new treatment strategy for achalasia. Although several kinds of electrosurgical knives have been used in performing POEM, the best device has yet to be determined. The FlushKnife BT is a waterjet-emitting short needle-knife with a small ball tip (BT) that offers the potential to perform all aspects of POEM with a single device. In this study, we evaluated the safety and efficiency of the FlushKnife BT for POEM.<\/jats:p><jats:p>\n          Patients and methods\u2002A total of 54 consecutive patients with achalasia and other spastic esophageal motility disorders, such as jackhammer esophagus or distal esophageal spasm, who underwent POEM between January 2016 and August 2016, were included in this retrospective study.<\/jats:p><jats:p>\n          Results\u2002The median operation time was 73.0 minutes (range 39\u200a\u2013\u200a184 minutes). All procedures were completed using only the FlushKnife BT without changing to any other electrosurgical instrument. The median number of additional submucosal injections with an injection needle was 0 (range 0\u200a\u2013\u200a1). Endoscopic vessel sealing was performed a mean of 3 times (range 0\u200a\u2013\u200a7). The median number of bleeding episodes requiring treatment with hemostatic forceps was 0 (range 0\u200a\u2013\u200a5). There were no significant adverse events. Seven of 52 patients (13.5\u200a%) reported symptoms of gastroesophageal reflux disease such as heartburn or acid reflux at 3 month follow-up.<\/jats:p><jats:p>\n          Conclusions\u2002The FlushKnife BT enabled POEM to be performed with very few device exchanges, either for re-injection or to control intraoperative bleeding. In this uncontrolled case series, the ability of the FlushKnife BT to perform nearly all aspects of the POEM procedure seems to make it particularly well suited to this procedure.<\/jats:p>","DOI":"10.1055\/s-0043-111721","type":"journal-article","created":{"date-parts":[[2017,7,6]],"date-time":"2017-07-06T23:33:35Z","timestamp":1499384015000},"page":"E663-E669","source":"Crossref","is-referenced-by-count":10,"title":["Peroral endoscopic myotomy using FlushKnife BT: a single-center series"],"prefix":"10.1055","volume":"05","author":[{"given":"Shinwa","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Graduate School of Medicine, Kobe University, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Toyonaga","sequence":"additional","affiliation":[{"name":"Department of Endoscopy, Kobe University Hospital, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumiaki","family":"Kawara","sequence":"additional","affiliation":[{"name":"Department of Endoscopy, Kobe University Hospital, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Grimm","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Namiko","family":"Hoshi","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Graduate School of Medicine, Kobe University, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirofumi","family":"Abe","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Graduate School of Medicine, Kobe University, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiko","family":"Ohara","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Graduate School of Medicine, Kobe University, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshinori","family":"Morita","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Graduate School of Medicine, Kobe University, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiji","family":"Umegaki","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Graduate School of Medicine, Kobe University, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Azuma","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Graduate School of Medicine, Kobe University, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2017,7,6]]},"container-title":["Endoscopy International Open"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0043-111721.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T18:54:45Z","timestamp":1557168885000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0043-111721"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":0,"journal-issue":{"issue":"07","published-online":{"date-parts":[[2017,6,23]]},"published-print":{"date-parts":[[2017,7]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0043-111721","relation":{},"ISSN":["2364-3722","2196-9736"],"issn-type":[{"value":"2364-3722","type":"print"},{"value":"2196-9736","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7]]}}}