{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T18:09:39Z","timestamp":1765303779922},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"23","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dtsch med Wochenschr"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Reasons for leukopenia can be numerous. To get close to the diagnosis it\u2019s always useful to check previous blood counts of the patient to get a feeling for the dynamic development of the leukopenia. Furthermore, it\u2019s important to check the red blood cell count and platelet count as well; a\u00a0bi- or a pancytopenia usually implies an insufficient production in the bone marrow. Nevertheless, a manual counted peripheral blood smear is an essential step towards the right diagnosis in leukopenia: Beside cell counts of the single subgroups of leucocytes it also provides information on potential causes such as dysplasia.<\/jats:p><jats:p>Leukopenia can be life-threatening for the patient especially if the patient presents with an agranulocytosis and fever: In this case admission is mandatory and the patient has to be treated immediately with broad-spectrum antibiotics to reduce mortality.<\/jats:p>","DOI":"10.1055\/s-0043-113123","type":"journal-article","created":{"date-parts":[[2017,11,16]],"date-time":"2017-11-16T23:41:40Z","timestamp":1510875700000},"page":"1744-1749","source":"Crossref","is-referenced-by-count":11,"title":["Leukopenie \u2013 ein diagnostischer Leitfaden f\u00fcr die Praxis"],"prefix":"10.1055","volume":"142","author":[{"given":"Deborah","family":"Christen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Br\u00fcmmendorf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Panse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2017,11,16]]},"container-title":["DMW - Deutsche Medizinische Wochenschrift"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0043-113123.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,12,20]],"date-time":"2017-12-20T06:15:12Z","timestamp":1513750512000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0043-113123"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":0,"journal-issue":{"issue":"23","published-online":{"date-parts":[[2017,11,16]]},"published-print":{"date-parts":[[2017,11]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0043-113123","relation":{},"ISSN":["0012-0472","1439-4413"],"issn-type":[{"value":"0012-0472","type":"print"},{"value":"1439-4413","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11]]}}}