{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T03:52:48Z","timestamp":1778212368888,"version":"3.51.4"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacopsychiatry"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\nIntroduction We present an online decision aid to involve patients with a psychotic disorder in shared decision-making concerning the selection of antipsychotic medication.<\/jats:p><jats:p>\nMethod Patients selected effectiveness and adverse effects criteria from the Subject\u2019s Response to Antipsychotics-34 questionnaire. Numerical data from meta-analyses, clinical trial data, receptor affinities and expert opinions were used to rank antipsychotics on each criterion. When using the the tool, patients indicate on a 5-point Likert scale how they value each (adverse) effect. The Likert scale values are combined in an algorithm with the rank orders of antipsychotics to create a personalized ranking.<\/jats:p><jats:p>\nResults Criteria used were: effectiveness concerning psychotic, depressive and cognitive symptoms, weight gain, sexual dysfunction, drowsiness, hypersomnia, extrapyramidal symptoms, anticholinergic adverse effects, hypersalivation, nausea, dizziness, energy loss, blunted affect\/less need for companionship. High-level evidence was available for ranking weight gain, sexual dysfunction, menstrual disorders, extrapyramidal symptoms and effectiveness on psychotic symptoms. We used lower level evidence ranking the remaining criteria.<\/jats:p><jats:p>\nDiscussion A transparent procedure has resulted in an updateable tool to produce individual ranking of antipsychotics based on the patients\u2019 input.<\/jats:p>","DOI":"10.1055\/s-0043-116854","type":"journal-article","created":{"date-parts":[[2017,8,15]],"date-time":"2017-08-15T22:38:09Z","timestamp":1502836689000},"page":"89-99","source":"Crossref","is-referenced-by-count":13,"title":["The Personal Antipsychotic Choice Index"],"prefix":"10.1055","volume":"51","author":[{"given":"Floor","family":"van Dijk","sequence":"additional","affiliation":[{"name":"Department Early Psychosis, Academical Medical Centre of the University of Amsterdam, Amterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iris","family":"de Wit","sequence":"additional","affiliation":[{"name":"Department Early Psychosis, Academical Medical Centre of the University of Amsterdam, Amterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthijs","family":"Blankers","sequence":"additional","affiliation":[{"name":"Department of Research, Arkin Mental Health Care, Amsterdam, the Netherlands"},{"name":"Trimbos-institute, the Netherlands institute of mental health and addiction, Utrecht, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iris","family":"Sommer","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Brain Center Rudolf Magnus, Utrecht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lieuwe","family":"de Haan","sequence":"additional","affiliation":[{"name":"Department Early Psychosis, Academical Medical Centre of the University of Amsterdam, Amterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2017,8,15]]},"container-title":["Pharmacopsychiatry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0043-116854.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,5,9]],"date-time":"2018-05-09T22:41:44Z","timestamp":1525905704000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0043-116854"}},"subtitle":["Introducing a Tool for Shared Decision-Making in Selecting Antipsychotic Medication"],"short-title":[],"issued":{"date-parts":[[2017,8,15]]},"references-count":0,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2018,5,9]]},"published-print":{"date-parts":[[2018,5]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0043-116854","relation":{},"ISSN":["0176-3679","1439-0795"],"issn-type":[{"value":"0176-3679","type":"print"},{"value":"1439-0795","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,15]]}}}