{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T23:24:11Z","timestamp":1785540251454,"version":"3.56.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fortschr R\u00f6ntgenstr"],"published-print":{"date-parts":[[2018,2]]},"abstract":"\n Purpose\u2002To assess the performance of fat-suppressed fluid-sensitive MRI sequences compared to T1-weighted (T1w) \/ T2w sequences for the detection of Modic 1 end-plate changes on lumbar spine MRI.<\/jats:p>\n Materials and Methods\u2002Sagittal T1w, T2w, and fat-suppressed fluid-sensitive MRI images of 100 consecutive patients (consequently 500 vertebral segments; 52 female, mean age 74\u200a\u00b1\u200a7.4 years; 48 male, mean age 71\u200a\u00b1\u200a6.3 years) were retrospectively evaluated. We recorded the presence (yes\/no) and extension (i.\u200ae., Likert-scale of height, volume, and end-plate extension) of Modic I changes in T1w\/T2w sequences and compared the results to fat-suppressed fluid-sensitive sequences (McNemar\/Wilcoxon-signed-rank test).<\/jats:p>\n Results\u2002Fat-suppressed fluid-sensitive sequences revealed significantly more Modic I changes compared to T1w\/T2w sequences (156 vs. 93 segments, respectively; p\u200a<\u200a0.001). The extension of Modic I changes in fat-suppressed fluid-sensitive sequences was significantly larger compared to T1w\/T2w sequences (height: 2.53\u200a\u00b1\u200a0.82 vs. 2.27\u200a\u00b1\u200a0.79, volume: 2.35\u200a\u00b1\u200a0.76 vs. 2.1\u200a\u00b1\u200a0.65, end-plate: 2.46\u200a\u00b1\u200a0.76 vs. 2.19\u200a\u00b1\u200a0.81), (p\u200a<\u200a0.05). Modic I changes that were only visible in fat-suppressed fluid-sensitive sequences but not in T1w\/T2w sequences were significantly smaller compared to Modic I changes that were also visible in T1w\/T2w sequences (p\u200a<\u200a0.05).<\/jats:p>\n Conclusion\u2002In conclusion, fat-suppressed fluid-sensitive MRI sequences revealed significantly more Modic I end-plate changes and demonstrated a greater extent compared to standard T1w\/T2w imaging.<\/jats:p>\n Key Points\u2002<\/jats:p>\n Citation Format\n <\/jats:p>","DOI":"10.1055\/s-0043-118130","type":"journal-article","created":{"date-parts":[[2017,11,27]],"date-time":"2017-11-27T18:43:30Z","timestamp":1511808210000},"page":"152-160","source":"Crossref","is-referenced-by-count":6,"title":["Modic Type 1 Changes: Detection Performance of Fat-Suppressed Fluid-Sensitive MRI Sequences"],"prefix":"10.1055","volume":"190","author":[{"given":"Tim","family":"Finkenstaedt","sequence":"additional","affiliation":[{"name":"Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Del Grande","sequence":"additional","affiliation":[{"name":"Institute of Diagnostic and Interventional Radiology, Ospedale Regionale di Lugano, Lugano, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolae","family":"Bolog","sequence":"additional","affiliation":[{"name":"Phoenix Diagnostic Clinic, Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils","family":"Ulrich","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Spine Center, Schulthess Clinic, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sina","family":"Tok","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Spine Center, Schulthess Clinic, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orpheus","family":"Kolokythas","sequence":"additional","affiliation":[{"name":"Institute for Radiology and Nuclear Medicine, Kantonsspital Winterthur, Winterthur, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johann","family":"Steurer","sequence":"additional","affiliation":[{"name":"Horten Center for patient oriented research and knowledge transfer, University Hospital Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustav","family":"Andreisek","sequence":"additional","affiliation":[{"name":"Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Winklhofer","sequence":"additional","affiliation":[{"name":"Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland"},{"name":"Department of Neuroradiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the LSOS Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2017,11,27]]},"container-title":["R\u00f6Fo - Fortschritte auf dem Gebiet der R\u00f6ntgenstrahlen und der bildgebenden Verfahren"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0043-118130.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,18]],"date-time":"2018-01-18T18:35:46Z","timestamp":1516300546000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0043-118130"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,27]]},"references-count":0,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2018,1,18]]},"published-print":{"date-parts":[[2018,2]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0043-118130","relation":{},"ISSN":["1438-9029","1438-9010"],"issn-type":[{"value":"1438-9029","type":"print"},{"value":"1438-9010","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,27]]}}}