{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T14:57:28Z","timestamp":1673449048757},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Horm Metab Res"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The objective was to determine whether negative assessment after surgery is a predictor of no relevant change of the results in subsequent evaluations in patients with noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). Six months after surgery, \u201cabsence of persistent disease\u201d was defined when concentration of thyroglobulin (Tg) is \u22642\u2009ng\/ml in patients undergoing total thyroidectomy and \u226410\u2009ng\/ml in those undergoing lobectomy, in the absence of antithyroglobulin antibodies (TgAb), and neck ultrasonography (US) without abnormalities. One hundred thirteen patients met the definition of \u201cabsence of persistent disease\u201d. The patients were followed up for 18\u2013150 months. None of the patients developed structural disease. In the 56 patients undergoing total thyroidectomy, 380\u2009Tg measurements were obtained and an increase in concentrations was not observed in any of them. During the same period, 332 US scans were performed and a suspicious lymph node was detected on only one occasion, but was not metastatic on fine needle aspiration (FNA). In the 57 patients undergoing lobectomy, 382\u2009Tg measurements were obtained and increases or persistent concentrations&gt;10\u2009ng\/ml were not observed in any patient. During the same period, 376 US scans were performed and nodules with an indication for FNA were detected in 4 patients, but malignancy was not confirmed in any of them. Finally, TgAb were not elevated in any of the 762 measurements obtained from the 113 patients. After complete resection of NIFTP, negative postoperative assessment can be used to exclude the need for long-term repetition of these tests.<\/jats:p>","DOI":"10.1055\/s-0043-121707","type":"journal-article","created":{"date-parts":[[2017,11,9]],"date-time":"2017-11-09T18:46:01Z","timestamp":1510253161000},"page":"223-226","source":"Crossref","is-referenced-by-count":3,"title":["Long-Term Follow-Up in Patients with Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP) Without a Suspicion of Persistent Disease in Postoperative Assessment"],"prefix":"10.1055","volume":"50","author":[{"given":"Pedro","family":"Rosario","sequence":"additional","affiliation":[{"name":"Postgraduate Program, Santa Casa de Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela","family":"Mour\u00e3o","sequence":"additional","affiliation":[{"name":"Endocrinology Service, Santa Casa de Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu\u00eds","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Universidade de Ita\u00fana, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Calsolari","sequence":"additional","affiliation":[{"name":"Postgraduate Program, Santa Casa de Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2017,11,9]]},"container-title":["Hormone and Metabolic Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0043-121707.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,3,9]],"date-time":"2018-03-09T18:34:21Z","timestamp":1520620461000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0043-121707"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,9]]},"references-count":0,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2018,3,9]]},"published-print":{"date-parts":[[2018,3]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0043-121707","relation":{},"ISSN":["0018-5043","1439-4286"],"issn-type":[{"value":"0018-5043","type":"print"},{"value":"1439-4286","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,9]]}}}