{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T11:22:39Z","timestamp":1770290559290,"version":"3.49.0"},"reference-count":13,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003The effect of continuous myocardial perfusion (CMP) on the surgical results of acute type A aortic dissection (ATAAD) remains unclear.<\/jats:p><jats:p>\n          Methods\u2003From January 2017 to March 2022, 141 patients who underwent ATAAD (90.8%) or intramural hematoma (9.2%) surgery were reviewed. Fifty-one patients (36.2%) received proximal-first aortic reconstruction and CMP during distal anastomosis. Ninety patients (63.8%) underwent distal-first aortic reconstruction and were placed in traditional cold blood cardioplegic arrest (CA; 4\u00b0C, 4:1 blood-to-Plegisol) throughout the procedure. The preoperative presentations and intraoperative details were balanced using inverse probability of treatment weighting (IPTW). Their postoperative morbidity and mortality were analyzed.<\/jats:p><jats:p>\n          Results\u2003The median age was 60 years. The incidence of arch reconstruction in the unweighted data was higher in the CMP compared with the CA group (74.5 vs 52.2%, p\u2009=\u20090.017) but was balanced after IPTW (62.4 vs 58.9%, p\u2009=\u20090.932, standardized mean difference\u2009=\u20090.073). The median cardiac ischemic time was lower in the CMP group (60.0 vs 130.9\u2009minutes, p\u2009&lt;\u20090.001), but cerebral perfusion time and cardiopulmonary bypass time were similar. The CMP group did not demonstrate any benefit in the reduction of the postoperative maximum creatine kinase-MB ratio (4.4 vs 5.1% in CA, p\u2009=\u20090.437) or postoperative low cardiac output (36.6 vs 24.8%, p\u2009=\u20090.237). Surgical mortality was comparable between groups (15.5% in CMP vs 7.5% in the CA group, p\u2009=\u20090.265).<\/jats:p><jats:p>\n          Conclusion\u2003Application of CMP during distal anastomosis in ATAAD surgery, irrespective of the extent of aortic reconstruction, reduced myocardial ischemic time but did not improve cardiac outcome or mortality.<\/jats:p>","DOI":"10.1055\/s-0043-1761218","type":"journal-article","created":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T23:50:50Z","timestamp":1677109850000},"page":"096-104","source":"Crossref","is-referenced-by-count":3,"title":["Continuous Myocardial Perfusion during Distal Anastomosis of Acute Type A Aortic Dissection"],"prefix":"10.1055","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1058-0443","authenticated-orcid":false,"given":"Chia-Yu","family":"Ou","sequence":"additional","affiliation":[{"name":"Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsiang-Wei","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ting-Wei","family":"Lin","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Department of Surgery, E-Da Hospital\/I-Shou University, Kaohsiung, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun-Neng","family":"Roan","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Ning","family":"Hu","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Cheng","family":"Wang","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3893-4645","authenticated-orcid":false,"given":"Meng-Ta","family":"Tsai","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan"},{"name":"Institue of Clinical Pharmacy and Pharmaceutical Sciences, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,2,22]]},"reference":[{"issue":"02","key":"ref1","first-page":"159","article-title":"Safety time and optimal temperature of unilateral antegrade cerebral perfusion in acute type A aortic dissection: a single-center 15-year experience","volume":"38","author":"M T Tsai","year":"2022","journal-title":"Acta Cardiol Sin"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/S0003-4975(00)01638-6","article-title":"Reperfusion injury associated with one-fourth of deaths after coronary artery bypass grafting","volume":"70","author":"S M Weman","year":"2000","journal-title":"Ann Thorac Surg"},{"issue":"01","key":"ref3","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1093\/ejcts\/ezv009","article-title":"Do not leave the heart arrested. 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