{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:34:01Z","timestamp":1740126841202,"version":"3.37.3"},"reference-count":14,"publisher":"Georg Thieme Verlag KG","issue":"S 01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>\n            Objective\u2003The aim of the study is to assess the correlation of renal regional tissue saturation of oxygen (RrSO2) measured by near-infrared spectroscopy (NIRS) in preterm neonates to venous oxygen saturation (SvO2) obtained from umbilical venous catheters (UVCs), arterial oxygen saturation (SaO2) obtained from umbilical artery catheters (UACs), and capillary oxygen saturation (ScO2) from capillary heel blood draws.<\/jats:p><jats:p>\n            Study Design\u2003A secondary analysis of a prospective RrSO2 monitoring study in preterm neonates born &lt;32 weeks gestational age. Neonates with any blood gas obtained during RrSO2 monitoring were included. RrSO2 was compared with simultaneous O2 saturation using non-parametric Mann Whitney U-test and Spearman correlation coefficient.<\/jats:p><jats:p>\n            Results\u2003In 35 neonates, 25 UVC, 151 UAC, and 68 heel capillary specimens were obtained. RrSO2 was lower than the median SvO2 (58.8 vs. 78.9, p &lt;0.01), SaO2 (51.0 vs. 93.2, p &lt;0.01), and ScO2 (62.2 vs. 94.25, p &lt;0.01). RrSO2 values correlated to both SaO2 and ScO2 (r\u2009=\u20090.32; p &lt;0.01, r\u2009=\u20090.26; p\u2009=\u20090.03), but not SvO2 (r\u2009=\u20090.07; p\u2009=\u20090.74).<\/jats:p><jats:p>\n            Conclusion\u2003In this secondary analysis, RrSO2 was consistently lower than blood gas O2 saturations and correlated with SaO2 and ScO2 but not SvO2. Lack of a correlation to SvO2 could be due to the small UVC sample size limiting statistical power. Future studies should prospectively evaluate if RrSO2 truly primarily reflects venous oxygenation in preterm neonates.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0043-1761296","type":"journal-article","created":{"date-parts":[[2023,1,29]],"date-time":"2023-01-29T23:34:00Z","timestamp":1675035240000},"page":"e1228-e1234","source":"Crossref","is-referenced-by-count":0,"special_numbering":"S","title":["Correlation of Renal Tissue Oxygenation to Venous, Arterial, and Capillary Blood Gas Oxygen Saturation in Preterm Neonates"],"prefix":"10.1055","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5493-3269","authenticated-orcid":false,"given":"Matthew W.","family":"Harer","sequence":"additional","affiliation":[{"name":"University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin"},{"name":"Division of Neonatology, Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren","family":"Gadek","sequence":"additional","affiliation":[{"name":"University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy C.","family":"Rothwell","sequence":"additional","affiliation":[{"name":"University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luke","family":"Richard","sequence":"additional","affiliation":[{"name":"University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9412-8950","authenticated-orcid":false,"given":"Michelle C.","family":"Starr","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana"},{"name":"Pediatric and Adolescent Comparative Effectiveness Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudette O.","family":"Adegboro","sequence":"additional","affiliation":[{"name":"University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin"},{"name":"Division of Neonatology, Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,1,29]]},"reference":[{"issue":"03","key":"ref1","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S2352-4642(17)30069-X","article-title":"Incidence and outcomes of neonatal acute kidney injury (AWAKEN): a multicentre, multinational, observational cohort study","volume":"1","author":"J G Jetton","year":"2017","journal-title":"Lancet Child Adolesc Health"},{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/nep.12357","article-title":"Is renal tissue oxygen desaturation during severe hypoxia underestimated? 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