{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T11:58:21Z","timestamp":1781179101079,"version":"3.54.1"},"reference-count":17,"publisher":"Scientific Scholar","issue":"02","license":[{"start":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T00:00:00Z","timestamp":1678320000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["South Asian J Cancer"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:p>Background\u2003Surgical site infections (SSIs) in head and neck cancer (HNC) patients can significantly affect the outcome of the surgery. Appropriate antimicrobial prophylaxis is needed for prevention of SSI.<\/jats:p>\n                  <jats:p>Aim\u2003To study the causative agents causing SSI among the HNC patients and their drug resistance pattern.<\/jats:p>\n                  <jats:p>Materials and Methods\u2003This was a retrospective study. The antibiotic suspectibility pattern of the aerobic bacteria isolated from the wound infection in the patients underwent surgery for head and neck cancer, admitted from January 2015 to December 2016 were added in the study. The demographic details of patients, pathogens isolated, and their antimicrobial susceptibility were collected, entered into Microsoft Excel, and statistical analysis was done as per percentage of isolates and drug resistance.<\/jats:p>\n                  <jats:p>Results\u2003A total of 130 culture-positive pus samples were included in the study. The majority of the samples were from males (71.5%), one-third of the patients belonged to the sixth decade of their life. Buccal mucosa and tongue were the common cancer in the head and neck region. The common gram-negative pathogens were Klebsiella sp. and Acinetobacter sp. and Staphylococcus aureus and Enterococcus sp. among the gram-positive bacteria. Methicillin-resistant S. aureus isolation rate was noted to be as high as 64.28%. High levels of resistance to aminopenicillins, third generation cephalosporins, co-trimoxazole and fluoroquinolones among the gram-negative pathogens. Anti-MRSA drugs such as vancomycin, linezolid, and teicoplanin resistance was not seen among S. aureus.<\/jats:p>\n                  <jats:p>Conclusion\u2003The resistance pattern among the pathogens isolated from SSI in HNC patients is alarming. So, implementation of strict infection control practices to prevent SSI rather than treating them with high end antimicrobials is the best option.<\/jats:p>","DOI":"10.1055\/s-0043-1763282","type":"journal-article","created":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T19:20:04Z","timestamp":1678389604000},"page":"110-113","source":"Crossref","is-referenced-by-count":4,"title":["Surgical Site Infection in Head and Neck Cancer Patients: Observations from A Tertiary Care Hospital"],"prefix":"10.25259","volume":"13","author":[{"given":"Surlu Vidya","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Hospital Administration, Father Muller Medical College Hospital, Kankanady, Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Simon","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Father Muller Medical College Hospital, Kankanady, Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elroy","family":"Saldanha","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Father Muller Medical College Hospital, Kankanady, Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rekha","family":"Boloor","sequence":"additional","affiliation":[{"name":"Department of Microbiology\/Hospital Infection Control, Father Muller Medical College Hospital, Kankanady, Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramakrishna Pai","family":"Jakribettu","sequence":"additional","affiliation":[{"name":"Department of Microbiology\/Hospital Infection Control, Father Muller Medical College Hospital, Kankanady, Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manjeshwar Shrinath","family":"Baliga","sequence":"additional","affiliation":[{"name":"Father Muller Research Centre, Kankanady, Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2023,3,9]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"394","DOI":"10.3322\/caac.21492","article-title":"Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"68","author":"F Bray","year":"2018","journal-title":"CA Cancer J Clin"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1146\/annurev.pathol.4.110807.092158","article-title":"Molecular pathology of head and neck cancer: implications for diagnosis, prognosis, and treatment","volume":"4","author":"S I Pai","year":"2009","journal-title":"Annu Rev Pathol"},{"issue":"02","key":"ref3","first-page":"111","article-title":"Pattern of head and neck cancers among Nigerians in Lagos","volume":"20","author":"C C Nwawolo","year":"2001","journal-title":"West Afr J Med"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1136\/bmj.308.6934.961","article-title":"Cancer of the head and neck","volume":"308","author":"J S Tobias","year":"1994","journal-title":"BMJ"},{"issue":"01","key":"ref5","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1258\/0049475053001949","article-title":"Clinicopathological study of head and neck cancers in Ilorin, Nigeria","volume":"35","author":"F E Ologe","year":"2005","journal-title":"Trop Doct"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1093\/annonc\/mdp149","article-title":"Squamous cell carcinoma of the head and neck: ESMO clinical recommendations for diagnosis, treatment and follow-up","volume":"20","author":"L Licitra","year":"2009","journal-title":"Ann Oncol"},{"issue":"03","key":"ref7","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1097\/01.cco.0000160277.86386.dc","article-title":"The evolving role of surgery in the management of head and neck tumors","volume":"17","author":"G Andry","year":"2005","journal-title":"Curr Opin Oncol"},{"issue":"03","key":"ref8","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.oraloncology.2004.08.011","article-title":"Multivariate analysis of risk factors for wound infection in head and neck squamous cell carcinoma surgery with opening of mucosa. 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