{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T11:58:21Z","timestamp":1781179101111,"version":"3.54.1"},"reference-count":12,"publisher":"Scientific Scholar","issue":"01","license":[{"start":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T00:00:00Z","timestamp":1681084800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["South Asian J Cancer"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>Areca nut consumption is embedded in many cultures, including that of Bhutan, several parts of India, and other South Eastern countries. Traditional fermenting of areca nut results in the production of what is called doma in Bhutan. The process enhances its carcinogenic potential and is tightly linked to oral and upper gastrointestinal cancers. As many as 45% of Bhutanese people chew doma. It is the number one cause of cancers of the oral cavity, oropharynx, hypopharynx, and larynx. We propose the slogan \u201cDon't chew your way to cancer, say no to doma\u201d would help in reducing oral and esophageal cancers in Bhutan.<\/jats:p>","DOI":"10.1055\/s-0043-1764216","type":"journal-article","created":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T18:47:45Z","timestamp":1681152465000},"page":"001-003","source":"Crossref","is-referenced-by-count":1,"title":["Chewing Doma (Fermented Betel Nut): Culture versus Cancer?"],"prefix":"10.25259","volume":"13","author":[{"given":"Amol","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, INHS ASVINI, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manali","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Jaslok Hospital, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phub","family":"Tshering","sequence":"additional","affiliation":[{"name":"Department of Oncology, Jigme Dorji Wangchuk National Referral Hospital, Thimphu, Bhutan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venkata Pradeep Babu","family":"Koyyala","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Tezpur Cancer Centre, Tezpur, Assam, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikhil","family":"Ghadyalpatil","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Yashoda Hospital, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2023,4,10]]},"reference":[{"key":"ref3","doi-asserted-by":"publisher","first-page":"1024","DOI":"10.3332\/ecancer.2020.1024","article-title":"Epidemiological and histopathological characteristics of head and neck cancers in Bhutan from 2011 to 2017: a retrospective descriptive study","volume":"14","author":"P Tshering","year":"2020","journal-title":"Ecancermedicalscience"},{"key":"ref4","first-page":"785","volume-title":"Oral and systemic health effects of compulsive areca nut use","author":"S Cox","year":"2016"},{"issue":"08","key":"ref5","doi-asserted-by":"publisher","first-page":"e42759","DOI":"10.1371\/journal.pone.0042759","article-title":"Association of betel nut with carcinogenesis: revisit with a clinical perspective","volume":"7","author":"R N Sharan","year":"2012","journal-title":"PLoS One"},{"issue":"02","key":"ref6","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1002\/(SICI)1097-0215(19980119)75:2<225::AID-IJC10>3.0.CO;2-C","article-title":"Evaluation of carcinogenic\/co-carcinogenic activity of a common chewing product, pan masala, in mouse skin, stomach and esophagus","volume":"75","author":"A G Ramchandani","year":"1998","journal-title":"Int J Cancer"},{"issue":"04","key":"ref7","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.jef.2016.11.010","article-title":"A study on indigenous fermented foods and beverages of Kokrajhar, Assam, India","volume":"3","author":"Y Narzary","year":"2016","journal-title":"J Ethn Foods."},{"issue":"09","key":"ref8","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1080\/10826084.2019.1673416","article-title":"Prevalence and correlates of betel quid chewing among Bhutanese adults","volume":"55","author":"K Wangdi","year":"2020","journal-title":"Subst Use Misuse"},{"issue":"01","key":"ref9","doi-asserted-by":"crossref","first-page":"69","DOI":"10.4103\/0973-029X.157205","article-title":"Various terminologies associated with areca nut and tobacco chewing: a review","volume":"19","author":"K A Patidar","year":"2015","journal-title":"J Oral Maxillofac Pathol"},{"issue":"01","key":"ref10","first-page":"33","article-title":"Fate of betel nut chemical constituents following nut treatment prior to chewing and its relation to oral precancerous & cancerous lesion","volume":"10","author":"M N Awang","year":"1988","journal-title":"Dent J Malays"},{"key":"ref14","author":"U Ahuja"},{"key":"ref15","author":"J Farrar","year":"2013"},{"key":"ref17","author":"A Guti\u00e9rrez"},{"issue":"05","key":"ref19","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1054\/bjoc.2001.1920","article-title":"Betel nut and tobacco chewing; potential risk factors of cancer of oesophagus in Assam, India","volume":"85","author":"R K Phukan","year":"2001","journal-title":"Br J Cancer"}],"container-title":["South Asian Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0043-1764216.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T11:12:51Z","timestamp":1781176371000},"score":1,"resource":{"primary":{"URL":"https:\/\/journal.sajc.org\/chewing-doma-fermented-betel-nut-culture-versus-cancer\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,10]]},"references-count":12,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2024,5,7]]},"published-print":{"date-parts":[[2024,1]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0043-1764216","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2278-330X","2278-4306"],"issn-type":[{"value":"2278-330X","type":"print"},{"value":"2278-4306","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,10]]}}}