{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T13:02:43Z","timestamp":1780318963662,"version":"3.54.1"},"reference-count":24,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T00:00:00Z","timestamp":1682553600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Dent"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The purpose of this case report was to evaluate an approach for enhanced clinical decision-making while providing minimally invasive treatment, using the combined International Caries Classification and Management System (ICCMS 4D) with hands-free fluorescence-enhanced loupes (Reveal, Designs for Vision Inc., New York City, NY, United States) and a chemo-mechanical caries removal agent (Papac\u00e1rie Duo Gel, Formula &amp; Acao, Sao Paulo, Brazil). In recent decades, a shift towards a conservative approach to caries management has developed. The use of adequate operative techniques and correct decision-making are of paramount importance for early caries detection and tooth-preserving operative care. The use of noninvasive fluorescence-based adjuncts for enhanced diagnostic accuracy has gained popularity. Fluorescence describes the absorption of photons by a molecule, followed by its partial emission at a longer wavelength. Fluorescence detection of bacterial activity is largely based on the red\/orange fluorescence emanating from bacterial metabolism, and has been shown to be found particularly in active caries and mature anaerobic plaque. The combined approach of using the standardized visual International Caries Detection and Assessment System (ICDAS) with fluorescence as an operative adjunct was shown to enhance the advantages of both systems. The approach may potentially increase detection sensitivity without compromising the specificity of the visual tactile method. A recent hands-free device is aimed to combine simultaneous diagnosis and therapy (theragnosis) using fluorescence, while overcoming possible obstacles to workflow continuity. The \u201cReveal\u201d fluorescence-enhanced loupes are fitted with a dual white light\/fluorescence light, and are said to allow the clinician to conduct any operational procedure with optional fluorescence guidance, from detection to caries removal, to treatment completion. Using the described method, a comprehensive pathway that emphasizes evidence-based information, correct clinical decision-making, and a minimally invasive therapeutic approach was proposed. The approach may represent a potential advancement in providing minimally invasive caries care.<\/jats:p>","DOI":"10.1055\/s-0043-1764423","type":"journal-article","created":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T22:58:00Z","timestamp":1682636280000},"page":"1356-1362","source":"Crossref","is-referenced-by-count":2,"title":["Enhanced Clinical Decision-Making and Delivery of Minimally Invasive Care Using the ICCMS4D Integrated with Hands-Free Fluorescence-Based Loupes and a Chemomechanical Caries Removal Agent"],"prefix":"10.1055","volume":"17","author":[{"given":"Gal","family":"Hiltch","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Federal University of Rio Grande do Sul\u2014UFRGS, Porto Alegre, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0937-9147","authenticated-orcid":false,"given":"Liviu","family":"Steier","sequence":"additional","affiliation":[{"name":"Department of Preventive and Restorative Sciences, Dental School, University of Pennsylvania- UPENN, Philadelphia, Pennsylvania, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8113-9260","authenticated-orcid":false,"given":"Jos\u00e9 Antonio Poli","family":"de Figueiredo","sequence":"additional","affiliation":[{"name":"Department of Morphological Sciences, Federal University of Rio Grande do Sul\u2013UFRGS, Porto Allegre, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,4,27]]},"reference":[{"issue":"02","key":"ref1","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1177\/0022034516639271","article-title":"Managing carious lesions: consensus recommendations on carious tissue removal","volume":"28","author":"F Schwendicke","year":"2016","journal-title":"Adv Dent 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