{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T21:07:43Z","timestamp":1786568863611,"version":"build-2736575974"},"reference-count":18,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2023,5,6]],"date-time":"2023-05-06T00:00:00Z","timestamp":1683331200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Radiol Imaging"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Infectious spondylodiscitis is a debilitating condition and evidence-based medicine dictates confirming the diagnosis before treatment. Computed tomography\u2013guided spinal biopsy plays a major role and hence we would like to determine its utility in current clinical practice.<\/jats:p><jats:p>\n          Purpose\u2003The purpose of this study is to determine the percentage of confirmatory positives of CT-guided spinal biopsy in patients who were clinicoradiologically diagnosed with infectious spondylitis.<\/jats:p><jats:p>\n          Material and Methods\u2003A retrospective analysis of patients who underwent CT-guided biopsy for suspected infectious spondylodiscitis from 2017 to 2021 in a tertiary medical center was done. The data were filtered and obtained from the electronic database of the institution.<\/jats:p><jats:p>\n          Results\u2003In all, 259 patients underwent CT-guided biopsy of the spine. The procedure provided confirmatory results in 149 (57.5%) biospecimens. Histopathology examination was confirmatory in 95 (36.6%) of the 241 biospecimens sent. The Mycobacteria Growth Indicator Tube (MGIT) was confirmatory in 51 (19.9%) of the 250 biospecimens sent and drug resistance was seen in 6\/51 (11.7%) biospecimens. Xpert TB provided confirmatory results in 72 (27.8%) of the 254 biospecimens sent and rifampicin resistance was seen in 16\/72 (22.2%) biospecimens. Bacterial culture was confirmatory in 29 (11.2%) of the 250 biospecimens sent. The complication documented in this study was 0.3%.<\/jats:p><jats:p>\n          Conclusion\u2003CT-guided spinal biopsy for suspected vertebral osteomyelitis is a safe and effective minimally invasive procedure. It demonstrates a positive yield in more than half of the patients. Knowing the outcome, the patients can be appropriately counseled prior to the procedure. CT-guided biopsy results were affected by prior administration of ATT (antitubercular therapy) in suspected tuberculous spondylitis patients.<\/jats:p>","DOI":"10.1055\/s-0043-1764491","type":"journal-article","created":{"date-parts":[[2023,5,6]],"date-time":"2023-05-06T22:30:16Z","timestamp":1683412216000},"page":"289-294","source":"Crossref","is-referenced-by-count":9,"title":["Computed Tomography\u2013Guided Spinal Biopsy in Suspected Infective Spondylodiscitis: An Institutional Review of Its Utility"],"prefix":"10.1055","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5608-8596","authenticated-orcid":false,"given":"Raj Chendur Abhishek","family":"Ravichandran","sequence":"additional","affiliation":[{"name":"Christian Medical College, Vellore, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0266-9106","authenticated-orcid":false,"given":"Rohit","family":"Amritanand","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Christian Medical College, Vellore, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5605-1646","authenticated-orcid":false,"given":"Vinu","family":"Moses","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, Division of Clinical Radiology, Christian Medical College, Vellore, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1895-6997","authenticated-orcid":false,"given":"Madhavi","family":"Kandagaddala","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, Division of Clinical Radiology, Christian Medical College, Vellore, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3265-4522","authenticated-orcid":false,"given":"Venkatesh","family":"Krishnan","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Christian Medical College, Vellore, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9187-5109","authenticated-orcid":false,"given":"Kenny Samuel","family":"David","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Christian Medical College, Vellore, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3029-6514","authenticated-orcid":false,"given":"Justin","family":"Arockiaraj","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Christian Medical College, Vellore, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4481-5562","authenticated-orcid":false,"given":"Harini","family":"Kulasekaran","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Christian Medical College, Vellore, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8947-1233","authenticated-orcid":false,"given":"Maya Pavalasseril","family":"Ganesan","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Christian Medical College, Vellore, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2893-5812","authenticated-orcid":false,"given":"Anne Jennifer","family":"Prabhu","sequence":"additional","affiliation":[{"name":"Department of Pathology, Christian Medical College, Vellore, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4290-496X","authenticated-orcid":false,"given":"Shyamkumar Nidugala","family":"Keshava","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, Division of Clinical Radiology, Christian Medical College, Vellore, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,5,6]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.jinf.2008.02.005","article-title":"Infectious spondylodiscitis","volume":"56","author":"L Cottle","year":"2008","journal-title":"J Infect"},{"issue":"05","key":"ref2","doi-asserted-by":"crossref","first-page":"280","DOI":"10.12968\/hosp.2004.65.5.13703","article-title":"Discitis","volume":"65","author":"K S Lam","year":"2004","journal-title":"Hosp Med"},{"issue":"118","key":"ref3","first-page":"190","article-title":"Vertebral body osteomyelitis: spectrum and natural history. 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