{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:33:42Z","timestamp":1740126822275,"version":"3.37.3"},"reference-count":29,"publisher":"Georg Thieme Verlag KG","issue":"09","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Reconstr Microsurg"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Abdominal wall reconstruction is challenging for surgeons and may be life altering for patients. There are scant high-quality studies on patient-reported outcomes following abdominal wall reconstruction. We assess long-term surgical and patient-reported outcomes of perforator-preserving open anterior component separation (OPP-ACS) following large ventral hernia repair.<\/jats:p><jats:p>\n          Methods\u2003A retrospective review of patients with large ventral hernia defects who underwent OPP-ACS performed by the authors (B.A.S., M.J.T.) was conducted between 2015 and 2019. Demographics, surgical history, operative details, outcomes, and complications were extracted. A validated questionnaire, Carolinas Comfort Scale (CCS), was used to assess postoperative quality of life.<\/jats:p><jats:p>\n          Results\u2003Twenty-two patients (12 males and 10 females) with a mean age and BMI of 60.9\u2009\u00b1\u200910 years and 28.9\u2009\u00b1\u20094.8\u2009kg\/m2, respectively, were included. Mean follow-up was 28.5\u2009\u00b1\u200916.3 months. All had prior abdominal surgery; 15 (68%) for abdominopelvic malignancy, 3 (14%) for previous failed hernia repair, and 8 (36%) had history of abdominopelvic radiation. Overall, 16 (73%) hernias were in the midline, 4 (18%) in the right lower quadrant, 1 (4.5%) in the right upper quadrant, and 1 (4.5%) in the left lower quadrant. Mean hernia defect surface area was 145\u2009\u00b1\u2009112\u2009cm2. A total of 9 patients (40.9%) underwent bilateral component separation, whereas 13 (59.1%) had unilateral. Bioprosthetic mesh was used in all patients as underlay. Mean mesh size and thickness were 545.6\u2009\u00b1\u2009207.7\u2009cm2 and 3.4\u2009\u00b1\u20090.5\u2009mm, respectively. One patient presented with a minor wound dehiscence, and two presented with seromas not requiring aspiration\/evacuation. One patient had hernia recurrence 22 months after surgery. One patient was readmitted for partial small bowel obstruction and one required wound revision. A total of 14 (65%) patients responded to the CCS questionnaire. At 12 months, mean score for all 23 items was 0.29\u2009\u00b1\u20090.21 (0.08\u20130.62), which corresponds to absence or minimal symptoms.<\/jats:p><jats:p>\n          Conclusion\u2003The OPP-ACS is a safe surgical option for large, complex ventral hernias. Our cases showed minimal complication rate and hernia recurrence, and our patients reported significant improvement in life quality.<\/jats:p>","DOI":"10.1055\/s-0043-1768217","type":"journal-article","created":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T23:12:14Z","timestamp":1682550734000},"page":"743-750","source":"Crossref","is-referenced-by-count":1,"title":["Surgical and Patient-Reported Outcomes of Open Perforator-Preserving Anterior Component Separation for Ventral Hernia Repair"],"prefix":"10.1055","volume":"39","author":[{"given":"Samyd S.","family":"Bustos","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7008-5033","authenticated-orcid":false,"given":"Doga","family":"Kuruoglu","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark J.","family":"Truty","sequence":"additional","affiliation":[{"name":"Division of Hepato-Pancreatico-Biliary Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Basel A.","family":"Sharaf","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,4,26]]},"reference":[{"issue":"11","key":"ref1","doi-asserted-by":"crossref","first-page":"4104","DOI":"10.1007\/s00464-013-3075-4","article-title":"Current national practice patterns for inpatient management of ventral abdominal wall hernia in the United States","volume":"27","author":"L M Funk","year":"2013","journal-title":"Surg Endosc"},{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.jamcollsurg.2015.04.026","article-title":"Adverse events after ventral hernia repair: the vicious cycle of complications","volume":"221","author":"J L Holihan","year":"2015","journal-title":"J Am Coll Surg"},{"issue":"01","key":"ref3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1089\/sur.2015.124","article-title":"Component separation vs. bridged repair for large ventral hernias: a multi-institutional risk-adjusted comparison, systematic review, and meta-analysis","volume":"17","author":"J L Holihan","year":"2016","journal-title":"Surg Infect (Larchmt)"},{"issue":"01","key":"ref4","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1097\/00000658-200301000-00018","article-title":"Have outcomes of incisional hernia repair improved with time? 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