{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T03:53:59Z","timestamp":1777521239197,"version":"3.51.4"},"reference-count":74,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Semin Neurol"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>COVID-19 has been associated with numerous neurological complications, with acute cerebrovascular disease being one of the most devastating complications. Ischemic stroke is the most common cerebrovascular complication of COVID-19, affecting between 1 and 6% of all patients. Underlying mechanisms for COVID-related ischemic strokes are thought to be due to vasculopathy, endotheliopathy, direct invasion of the arterial wall, and platelet activation. Other COVID-19-associated cerebrovascular complications include hemorrhagic stroke, cerebral microbleeds, posterior reversible encephalopathy syndrome, reversible cerebral vasoconstriction syndrome, cerebral venous sinus thrombosis, and subarachnoid hemorrhage. This article discusses the incidence of these cerebrovascular complications, risk factors, management strategies, prognosis and future research directions, as well as considerations in pregnancy-related cerebrovascular events in the setting of COVID-19.<\/jats:p>","DOI":"10.1055\/s-0043-1768475","type":"journal-article","created":{"date-parts":[[2023,5,22]],"date-time":"2023-05-22T23:03:58Z","timestamp":1684796638000},"page":"219-228","source":"Crossref","is-referenced-by-count":6,"title":["COVID-19 and Cerebrovascular Disease"],"prefix":"10.1055","volume":"43","author":[{"given":"Christina","family":"Catherine","sequence":"additional","affiliation":[{"name":"Department of Neurology, UPMC Altoona Regional Hospital, Altoona, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Veitinger","sequence":"additional","affiliation":[{"name":"Division of Neurocritical Care, The Ken and Ruth Davee Department of Neurology, Northwestern Feinberg School of Medicine, Chicago, Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sherry H-Y.","family":"Chou","sequence":"additional","affiliation":[{"name":"Division of Neurocritical Care, The Ken and Ruth Davee Department of Neurology, Northwestern Feinberg School of Medicine, Chicago, Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,5,22]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"crossref","first-page":"e0107","DOI":"10.1097\/CCE.0000000000000107","article-title":"Neurologic manifestations of severe respiratory viral contagions","volume":"2","author":"C P Robinson","year":"2020","journal-title":"Crit Care Explor"},{"issue":"06","key":"ref2","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1001\/jamaneurol.2020.1127","article-title":"Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China","volume":"77","author":"L 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