{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T21:20:14Z","timestamp":1782249614793,"version":"3.54.5"},"reference-count":23,"publisher":"Georg Thieme Verlag KG","issue":"06","license":[{"start":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T00:00:00Z","timestamp":1687910400000},"content-version":"vor","delay-in-days":27,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Neuropsiquiatr"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Cognitive impairment (CI) during the acute phase of stroke should not be ignored. The present study analyzed the relationship between computed tomography perfusion (CTP) in different lobes and CI during the acute phase of stroke in patients with cerebral infarction.<\/jats:p><jats:p>\n          Methods\u2003The present study included 125 subjects: 96 in the acute phase of stroke and 29 elderly healthy subjects as a control group. The Montreal Cognitive Assessment (MoCA) was used to evaluate the cognitive status of the two groups. The CTP scans include four parameters: cerebral blood flow (CBF), cerebral blood volume (CBV), time to peak (TTP), and mean transit time (MTT).<\/jats:p><jats:p>\n          Results\u2003The MoCA scores for naming, language and delayed recall significantly decreased only in patients with left cerebral infarctions. The MTT of the left vessels in the occipital lobe and the CBF of the right vessels in the frontal lobe were negatively related to the MoCA scores of patients with left infarction. The CBV of the left vessels in the frontal lobe and the CBF of left vessels in the parietal lobe were positively linked to the MoCA scores of patients with left infarction. The CBF of the right vessels in the temporal lobe was positively related to the MoCA scores of patients with right infarction. Finally, the CBF of the left vessels in the temporal lobe was inversely correlated with the MoCA scores of patients with right infarctions.<\/jats:p><jats:p>\n          Conclusion\u2003During the acute phase of stroke, CTP was closely associated with CI. Changed CTP could be a potential neuroimaging biomarker to predict CI during the acute phase of stroke.<\/jats:p>","DOI":"10.1055\/s-0043-1768663","type":"journal-article","created":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T22:52:42Z","timestamp":1687992762000},"page":"524-532","source":"Crossref","is-referenced-by-count":2,"title":["Associations between cognitive impairment and computed tomography perfusion in different lobes in acute stroke of the anterior circulation"],"prefix":"10.1055","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6472-0347","authenticated-orcid":false,"given":"Mengna","family":"Chu","sequence":"additional","affiliation":[{"name":"Anhui Medical University, Second Affiliated Hospital, Department of Neurology, Hefei, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1193-3888","authenticated-orcid":false,"given":"Bin","family":"Dong","sequence":"additional","affiliation":[{"name":"Anhui Medical University, Third Affiliated Hospital, Department of Neurology, Hefei, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1434-0562","authenticated-orcid":false,"given":"Chao","family":"Huang","sequence":"additional","affiliation":[{"name":"Anhui Medical University, Third Affiliated Hospital, Department of Neurology, Hefei, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,6,28]]},"reference":[{"issue":"08","key":"ref1","first-page":"80","article-title":"Post-stroke cognitive impairment: epidemiology, mechanisms and management","volume":"2","author":"J H Sun","year":"2014","journal-title":"Ann Transl Med"},{"issue":"08","key":"ref2","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1136\/jnnp-2012-303645","article-title":"Cognitive impairment after lacunar stroke: systematic review and meta-analysis of incidence, prevalence and comparison with other stroke subtypes","volume":"84","author":"S D Makin","year":"2013","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"06","key":"ref3","doi-asserted-by":"crossref","first-page":"e98","DOI":"10.1161\/STR.0000000000000098","article-title":"Guidelines for Adult Stroke Rehabilitation and Recovery: A Guideline for Healthcare Professionals From the American Heart Association\/American Stroke Association","volume":"47","author":"C J Winstein","year":"2016","journal-title":"Stroke"},{"issue":"06","key":"ref4","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1161\/STROKEAHA.110.606277","article-title":"Is the Montreal Cognitive Assessment superior to the Mini-Mental State Examination to detect poststroke cognitive impairment? 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