{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T12:50:43Z","timestamp":1782737443643,"version":"3.54.5"},"reference-count":16,"publisher":"Georg Thieme Verlag KG","issue":"S 01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>\n            Objective\u2003This study aimed to evaluate the relationship between peripartum mean arterial pressure (MAP) and postpartum readmission for preeclampsia with severe features.<\/jats:p><jats:p>\n            Study Design\u2003This is a retrospective case\u2013control study comparing adult parturients readmitted for preeclampsia with severe features to matched nonreadmitted controls. Our primary objective was to evaluate the association between MAP at three time points during the index hospitalization (admission, 24-hour postpartum, and discharge) and readmission risk. We also evaluated readmission risk by age, race, body mass index, and comorbidities. Our secondary aim was to establish MAP thresholds to identify the population at highest risk of readmission. Multivariate logistic regression and chi-squared tests were used to determine the adjusted odds of readmission based on MAP. Receiver operating characteristic analyses were performed to evaluate risk of readmission relative to MAP; optimal MAP thresholds were established to identify those at highest risk of readmission. Pairwise comparisons were made between subgroups after stratifying for history of hypertension, with a focus on readmitted patients with new-onset postpartum preeclampsia.<\/jats:p><jats:p>\n            Results\u2003A total of 348 subjects met inclusion criteria, including 174 controls and 174 cases. We found that elevated MAP at both admission (adjusted odds ratio [OR]: 1.37 per 10\u2009mm Hg, p\u2009&lt;\u20090.0001) and 24-hour postpartum (adjusted OR: 1.61 per 10\u2009mm Hg, p\u2009=\u20090.0018) were associated with increased risk of readmission. African American race and hypertensive disorder of pregnancy were independently associated with increased risk of readmission. Subjects with MAP\u2009&gt;\u200999.5\u2009mm Hg at admission or &gt;91.5\u2009mm Hg at 24-hour postpartum had a risk of at least 46% of requiring postpartum readmission for preeclampsia with severe features.<\/jats:p><jats:p>\n            Conclusion\u2003Admission and 24-hour postpartum MAP correlate with risk of postpartum readmission for preeclampsia with severe features. Evaluating MAP at these time points may be useful for identifying women at higher risk for postpartum readmission. These women may otherwise be missed based on standard clinical approaches and may benefit from heightened surveillance.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0043-1770705","type":"journal-article","created":{"date-parts":[[2023,6,29]],"date-time":"2023-06-29T23:01:57Z","timestamp":1688079717000},"page":"e2188-e2194","source":"Crossref","is-referenced-by-count":3,"special_numbering":"S","title":["Association between Peripartum Mean Arterial Pressure and Postpartum Readmission for Preeclampsia with Severe Features"],"prefix":"10.1055","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6904-9684","authenticated-orcid":false,"given":"Bing-Xue","family":"Lin","sequence":"additional","affiliation":[{"name":"Franciscan Women's Health Associates, Tacoma, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, New York University Langone Health, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Sutter","sequence":"additional","affiliation":[{"name":"Rollins School of Public Health, Emory University, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8341-0379","authenticated-orcid":false,"given":"Christina A.","family":"Penfield","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynecology, New York University Langone Health,, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Proudfit","sequence":"additional","affiliation":[{"name":"Section of Maternal-Fetal Medicine, Cleveland Clinic, Cleveland, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,6,29]]},"reference":[{"issue":"03","key":"ref1","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1097\/HJH.0000000000001594","article-title":"Hypertensive disorders of pregnancy and postpartum readmission in the United States: national surveillance of the revolving door","volume":"36","author":"M F Mogos","year":"2018","journal-title":"J Hypertens"},{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1097\/AOG.0000000000002114","article-title":"Pregnancy-related mortality in the United States, 2011-2013","volume":"130","author":"A A Creanga","year":"2017","journal-title":"Obstet Gynecol"},{"issue":"01","key":"ref3","doi-asserted-by":"crossref","first-page":"113.e1","DOI":"10.1016\/j.ajog.2016.01.174","article-title":"A multi-state analysis of postpartum readmissions in the United States","volume":"215","author":"M A 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