{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T14:21:42Z","timestamp":1730816502964,"version":"3.28.0"},"reference-count":19,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Homeopathy"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Mastitis\u2013metritis\u2013agalactia (MMA) syndrome occurs in the first days post-partum and causes piglet losses mainly due to malnutrition. One possibility for prophylaxis of MMA is via homeopathy. In this veterinary study, the effectiveness of a prophylactic administration of homeopathic remedies for the prevention of the occurrence of MMA in swine was evaluated.<\/jats:p><jats:p>\n          Methods\u2003In a randomised and blinded study, 60 sows were examined. Sows were randomly distributed in two groups: the experimental group (CL\/LL) received a prophylactic administration of the complex homeopathic remedies Caulophyllum Logoplex and Lachesis Logoplex, and the placebo group was administered a sodium chloride (NaCl) solution in the same injection scheme as the experimental group. Clinical signs of MMA, behavioural changes, as well as production parameters, were recorded beginning with the day of farrowing until 5 days post-partum.<\/jats:p><jats:p>\n          Results\u2003The treatment group showed no significant effect on the occurrence of MMA in sows (CL\/LL: 56.67% MMA positive sows; NaCl: 53.53% MMA positive sows). Treatment group had also no significant effect on health parameters (vaginal discharge, raised rectal temperature, shortage of milk) or behavioural parameters (impaired feeding behaviour and impaired general condition). For the production parameter average weight gain, statistically significant effects in the treatment group were detected.<\/jats:p><jats:p>\n          Conclusions\u2003Prophylaxis with the homeopathic remedies Caulophyllum Logoplex and Lachesis Logoplex showed neither an improvement in MMA prevention nor an improvement in health parameters or behavioural traits in the present herd of sows.<\/jats:p>","DOI":"10.1055\/s-0043-1770725","type":"journal-article","created":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T22:41:03Z","timestamp":1693521663000},"page":"080-085","source":"Crossref","is-referenced-by-count":0,"title":["Randomised Controlled Trial on Prophylaxis of Mastitis\u2013Metritis\u2013Agalactia Syndrome in Swine using Caulophyllum Logoplex and Lachesis Logoplex"],"prefix":"10.1055","volume":"113","author":[{"given":"Kathrin","family":"B\u00fcttner","sequence":"additional","affiliation":[{"name":"Unit for Biomathematics and Data Processing, Justus-Liebig-University, Gie\u00dfen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janna","family":"Oelkers","sequence":"additional","affiliation":[{"name":"Institute of Animal Breeding and Husbandry, Christian-Albrechts-University, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Onno","family":"Burfeind","sequence":"additional","affiliation":[{"name":"Chamber of Agriculture of Schleswig-Holstein, Blekendorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joachim","family":"Krieter","sequence":"additional","affiliation":[{"name":"Institute of Animal Breeding and Husbandry, Christian-Albrechts-University, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irena","family":"Czycholl","sequence":"additional","affiliation":[{"name":"Department for Animal Welfare and Disease Control, University of Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,8,31]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1046\/j.1365-2885.2003.00524.x","article-title":"Investigation on the efficacy of meloxicam in sows with mastitis-metritis-agalactia syndrome","volume":"26","author":"A C Hirsch","year":"2003","journal-title":"J Vet Pharmacol Ther"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1093\/ecam\/nel117","article-title":"Immunology and homeopathy. 5. The rationale of the \u2018Simile\u2019","volume":"4","author":"P Bellavite","year":"2007","journal-title":"Evid Based Complement Alternat Med"},{"key":"ref3","first-page":"391","volume-title":"Versuch \u00fcber ein neues Prinzip zur Auffindung der Heilkr\u00e4fte der Arzneisubstanz","author":"S Hahnemann","year":"1796"},{"volume-title":"A Study of the Simile in Medicine","year":"1936","author":"L J Boyd","key":"ref4"},{"volume-title":"Hom\u00f6opathie Beim Schwein","year":"2016","author":"S Wesselmann","key":"ref5"},{"volume-title":"Praxisleitfaden Tierhom\u00f6opathie: Vom Arzneimittel Zum Leitsymptom","year":"2006","author":"C P Kr\u00fcger","key":"ref6"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1136\/vr.103779","article-title":"Efficacy of homeopathy in livestock according to peer-reviewed publications from 1981 to 2014","volume":"179","author":"C Doehring","year":"2016","journal-title":"Vet 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Camerlink","year":"2010","journal-title":"Homeopathy"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1186\/2046-4053-3-142","article-title":"Randomised placebo-controlled trials of individualised homeopathic treatment: systematic review and meta-analysis","volume":"3","author":"R T Mathie","year":"2014","journal-title":"Syst Rev"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.homp.2015.02.004","article-title":"Veterinary homeopathy: meta-analysis of randomised placebo-controlled trials","volume":"104","author":"R T Mathie","year":"2015","journal-title":"Homeopathy"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"72","DOI":"10.54846\/jshap\/846","article-title":"The course of rectal and vaginal temperature in early postpartum sows","volume":"23","author":"T Stiehler","year":"2015","journal-title":"J Swine Health Prod"},{"edition":"2nd edition.","volume-title":"Base SAS\u00ae 9.4 Procedures Guide: Statistical Procedures","author":"SAS Institute","key":"ref14"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"261","DOI":"10.3390\/agriculture10070261","article-title":"Pig farming in alternative systems: strengths and challenges in terms of animal welfare, biosecurity, animal health and pork safety","volume":"10","author":"M Delsart","year":"2020","journal-title":"Agriculture"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.3390\/ani3041021","article-title":"Animal health and welfare issues facing organic production systems","volume":"3","author":"M A Sutherland","year":"2013","journal-title":"Animals (Basel)"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S1573-5214(06)80005-9","article-title":"Animal health in organic livestock production systems: a review","volume":"54","author":"A Kijlstra","year":"2006","journal-title":"NJAS Wagening J Life 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