{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:18:10Z","timestamp":1791929890166,"version":"4.3.4"},"reference-count":28,"publisher":"Georg Thieme Verlag KG","issue":"S 01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>\n            Objective\u2003Our objective was to characterize the incidence, associated clinical factors, timing of infection, microbiology, and incidence of concordant blood culture of urinary tract infections (UTIs) in very low birth weight (VLBW &lt;1,500g) infants.<\/jats:p><jats:p>\n            Study Design\u2003Multicenter observational cohort study of VLBW infants with gestational age (GA) \u226432 weeks, still hospitalized on postnatal day 7, and discharged 2010 to 2018 from Pediatrix Medical Group neonatal intensive care units. Demographic and clinical characteristics of infants with and without UTI were compared. Multivariable logistic regression evaluated adjusted odds of UTI diagnosis.<\/jats:p><jats:p>\n            Results\u2003Of 86,492 included infants, 5,988 (7%) had a UTI. The most common pathogen was Enterococcus\n            spp. (20%), followed by Escherichia coli (19%) and Klebsiella\n            spp. (18%). Candida\n            spp. (6%) was the most common nonbacterial pathogen. Concordant-positive blood culture was present in 8% of infants with UTI diagnoses. UTI was associated with lower GA, male sex, vaginal delivery, prenatal steroid exposure, and longer duration of hospitalization.<\/jats:p><jats:p>\n            Conclusion\u2003UTI is a common cause of infection in VLBW infants, especially among the smallest, most premature, male infants, and those with a longer duration of hospitalization. Neonatal clinicians should consider obtaining urine culture in the setting of late-onset sepsis evaluations in VLBW infants.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0043-1771015","type":"journal-article","created":{"date-parts":[[2023,7,10]],"date-time":"2023-07-10T23:00:50Z","timestamp":1689030050000},"page":"e2202-e2208","source":"Crossref","is-referenced-by-count":11,"special_numbering":"S","title":["Urinary Tract Infection Epidemiology in NICUs in the United States"],"prefix":"10.1055","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1059-2401","authenticated-orcid":false,"given":"Ryan","family":"Kilpatrick","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Duke University Medical Center, Durham, North Carolina"},{"name":"Department of Pediatrics, Duke Clinical Research Institute, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelique E.","family":"Boutzoukas","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Duke University Medical Center, Durham, North Carolina"},{"name":"Department of Pediatrics, Duke Clinical Research Institute, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4953-093X","authenticated-orcid":false,"given":"Elizabeth","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Duke Clinical Research Institute, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie","family":"Girgis","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Duke Clinical Research Institute, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Kinduelo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Duke Clinical Research Institute, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah Ama","family":"Kwabia","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Duke Clinical Research Institute, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Duke Clinical Research Institute, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7363-4640","authenticated-orcid":false,"given":"Reese H.","family":"Clark","sequence":"additional","affiliation":[{"name":"Center for Research, Education, Quality, and Safety, Pediatrix Medical Group, Inc, Sunrise, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanecia O.","family":"Zimmerman","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Duke University Medical Center, Durham, North 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