{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T03:52:18Z","timestamp":1775620338317,"version":"3.50.1"},"reference-count":15,"publisher":"Georg Thieme Verlag KG","issue":"16","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:p>\n            Objective\u2003This article assesses the application of the Royal College of Obstetricians and Gynaecologists (RCOG) venous thromboembolism (VTE) risk model on a cohort of postpartum patients with a history of systemic lupus erythematosus (SLE).<\/jats:p><jats:p>\n            Study Design\u2003This is a secondary analysis of an ongoing patient registry of women with SLE from 2016 to 2022. There were 49 SLE patients with 55 pregnancies using the Definitions of Remission in SLE (DORIS) criteria to determine SLE disease activity. RCOG risk assessment model scoring was calculated for each patient prior to and after delivery. The primary outcome was the qualification of \u201cactive SLE\u201d by standard rheumatologic criteria and assessment of recommendations for VTE prophylaxis based on RCOG VTE risk assessment scoring. Data were analyzed using Fisher's exact test, chi-square test, and Mann\u2013Whitney U test with significance defined as p\u2009&lt;\u20090.05.<\/jats:p><jats:p>\n            Results\u2003In the study cohort, 34 pregnancies (61.8%) were in DORIS remission at delivery. Twenty-one pregnancies (38.2%) were not and scored 3 points on the RCOG VTE risk model. Of these pregnancies, only 19% (n\u2009=\u20094) were recommended for VTE prophylaxis by the obstetrical provider despite RCOG score \u22653. Only 35.7% (n\u2009=\u20095) of pregnancies in DORIS remission, but with 3 points for non-SLE-related VTE risk factors (n\u2009=\u200914), were recommended for VTE prophylaxis. Of the 20 pregnancies in remission with an RCOG score\u2009&lt;\u20093 after assessing all risk factors, 15% (n\u2009=\u20093) were nevertheless recommended for VTE prophylaxis. No patients had a postpartum VTE regardless of therapy.<\/jats:p><jats:p>\n            Conclusion\u2003These data reveal a need to improve upon providing postpartum VTE prophylaxis to SLE patients not in remission while also recognizing a diagnosis of SLE alone should not equate with active disease. Moreover, SLE patients in remission may still warrant VTE prophylaxis if other non-SLE-related risk factors are present.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0043-1771049","type":"journal-article","created":{"date-parts":[[2023,7,26]],"date-time":"2023-07-26T18:08:57Z","timestamp":1690394937000},"page":"1732-1737","source":"Crossref","is-referenced-by-count":2,"title":["Risk Assessment Model for Postpartum Venous Thromboembolism Prevention in Patients with Systemic Lupus Erythematosus"],"prefix":"10.1055","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7215-2965","authenticated-orcid":false,"given":"Myah M.","family":"Griffin","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, NYU Langone Health, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexis","family":"Engel","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, NYU Langone Health\/New York University Grossman School of Medicine, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8126-9631","authenticated-orcid":false,"given":"Shilpi S.","family":"Mehta-Lee","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, NYU Langone Health, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Nusbaum","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, NYU Langone Health\/New York University Grossman School of Medicine, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Golpanian","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, NYU Langone Health\/New York University Grossman School of Medicine, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Izmirly","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, NYU Langone Health\/New York University Grossman School of Medicine, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. Michael","family":"Belmont","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, NYU Langone Health\/New York University Grossman School of Medicine, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jill P.","family":"Buyon","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, NYU Langone Health\/New York University Grossman School of Medicine, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,7,20]]},"reference":[{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1097\/AOG.0000000000000564","article-title":"Pregnancy-related mortality in the United States, 2006-2010","volume":"125","author":"A A Creanga","year":"2015","journal-title":"Obstet Gynecol"},{"issue":"05","key":"ref3","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1097\/AOG.0b013e31826d60c5","article-title":"Severe maternal morbidity among delivery and postpartum hospitalizations in the United States","volume":"120","author":"W M Callaghan","year":"2012","journal-title":"Obstet Gynecol"},{"issue":"04","key":"ref4","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1111\/j.1538-7836.2008.02921.x","article-title":"Pregnancy, the postpartum period and prothrombotic defects: risk of venous thrombosis in the MEGA study","volume":"6","author":"E R Pomp","year":"2008","journal-title":"J Thromb Haemost"},{"issue":"03","key":"ref5","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1177\/1076029614553023","article-title":"Risk of venous thromboembolic events in pregnant patients with autoimmune diseases: a population-based study","volume":"22","author":"N Bleau","year":"2016","journal-title":"Clin Appl Thromb Hemost"},{"issue":"06","key":"ref6","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.3899\/jrheum.081194","article-title":"Determinants of risk for venous and arterial thrombosis in 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Caprini","year":"1991","journal-title":"Semin Thromb Hemost"},{"issue":"11","key":"ref10","doi-asserted-by":"crossref","first-page":"2450","DOI":"10.1111\/j.1538-7836.2010.04044.x","article-title":"A risk assessment model for the identification of hospitalized medical patients at risk for venous thromboembolism: the Padua Prediction Score","volume":"8","author":"S Barbar","year":"2010","journal-title":"J Thromb Haemost"},{"issue":"04","key":"ref11","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1097\/AOG.0000000000001656","article-title":"Pharmacologic thromboprophylaxis in obstetrics: broader use demands better data","volume":"128","author":"B M Sibai","year":"2016","journal-title":"Obstet Gynecol"},{"issue":"05","key":"ref13","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/j.ajog.2005.11.008","article-title":"Venous thromboembolism during pregnancy and the postpartum period: incidence, risk factors, and mortality","volume":"194","author":"A H James","year":"2006","journal-title":"Am J Obstet Gynecol"},{"issue":"24","key":"ref14","doi-asserted-by":"crossref","first-page":"2550","DOI":"10.1056\/NEJMoa051135","article-title":"Combined oral contraceptives in women with systemic lupus erythematosus","volume":"353","author":"M Petri","year":"2005","journal-title":"N Engl J Med"},{"issue":"02","key":"ref15","first-page":"288","article-title":"Systemic lupus erythematosus disease activity index 2000","volume":"29","author":"D D Gladman","year":"2002","journal-title":"J Rheumatol"},{"issue":"01","key":"ref16","doi-asserted-by":"crossref","first-page":"e000365","DOI":"10.1136\/lupus-2019-000365","article-title":"Scoring systemic lupus erythematosus (SLE) disease activity with simple, rapid outcome measures","volume":"6","author":"A Thanou","year":"2019","journal-title":"Lupus Sci Med"},{"issue":"01","key":"ref17","doi-asserted-by":"crossref","first-page":"x","DOI":"10.1136\/lupus-2021-000538","article-title":"2021 DORIS definition of remission in SLE: final recommendations from an international task force","volume":"8","author":"R F van Vollenhoven","year":"2021","journal-title":"Lupus Sci Med"}],"container-title":["American Journal of 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