{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T19:52:56Z","timestamp":1791402776853,"version":"4.3.3"},"reference-count":61,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T00:00:00Z","timestamp":1696896000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr Surg"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:p>\n            Background\u2003Surgical wound dehiscence (SWD) in neonates is a life-threatening complication. The aim was to define risk factors of postoperative incision dehiscence in this population.<\/jats:p><jats:p>\n            Methods\u2003Data of 144 patients from 2010 to 2020 were analyzed retrospectively. All full-term newborns or preterm newborns up to 42 weeks of amenorrhea (adjusted) who had a laparotomy within 30 days were included. Descriptive patient information and perioperative data were collected. SWD was defined as any separation of cutaneous edges of postoperative wounds.<\/jats:p><jats:p>\n            Results\u2003Overall, SWD occurred in 16\/144 (11%) patients, with a significantly increased incidence in preterm newborns (13\/59, 22%) compared with full-term newborns (3\/85, 4%; p\u2009&lt;\u20090.001). SWD was significantly associated with exposure to postnatal steroids (60% vs. 4%, p\u2009&lt;\u20090.001) and nonsteroidal anti-inflammatory drugs (25% vs. 4%, p\u2009&lt;\u20090.01), invasive ventilation duration before surgery (median at 10 vs. 0 days, p\u2009&lt;\u20090.001), preoperative low hemoglobin concentration (115 vs. 147\u2009g\/L, p\u2009&lt;\u20090.001) and platelet counts (127 vs. 295 G\/L, p\u2009&lt;\u20090.001), nonabsorbable suture material (43% vs. 8%, p\u2009&lt;\u20090.001), the presence of ostomies (69% vs. 18%, p\u2009&lt;\u20090.001), positive bacteriological wound cultures (50% vs. 6%, p\u2009&lt;\u20090.001), and relaparotomy (25% vs. 3%, p\u2009&lt;\u20090.01). Thirteen of 16 patients with SWD presented necrotizing enterocolitis\/intestinal perforations (81%, p\u2009&lt;\u20090.001).<\/jats:p><jats:p>\n            Conclusion\u2003This study identified prematurity and a number of other factors linked to the child's general condition as risk factors for SWD. Some of these can help physicians recognize and respond to at-risk patients and provide better counseling for parents.<\/jats:p>","DOI":"10.1055\/s-0043-1771223","type":"journal-article","created":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T22:59:56Z","timestamp":1696978796000},"page":"351-362","source":"Crossref","is-referenced-by-count":3,"title":["Risk Factors for Dehiscence of Operative Incisions in Newborns after Laparotomy"],"prefix":"10.1055","volume":"34","author":[{"given":"Tina B. S.","family":"Miholjcic","sequence":"additional","affiliation":[{"name":"Division of Child and Adolescent Surgery, Department of Pediatrics, Gynecology, and Obstetrics, Geneva University Hospitals, Geneva, Switzerland"},{"name":"Faculty of Medicine, University of Geneva, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Baud","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Geneva, Geneva, Switzerland"},{"name":"Division of Neonatal and Pediatric Intensive Care, Department of Pediatrics, Gynecology, and Obstetrics, Geneva University Hospitals, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pouya","family":"Iranmanesh","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Geneva, Geneva, Switzerland"},{"name":"Division of Digestive Surgery, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara E.","family":"Wildhaber","sequence":"additional","affiliation":[{"name":"Division of Child and Adolescent Surgery, Department of Pediatrics, Gynecology, and Obstetrics, Geneva University Hospitals, Geneva, Switzerland"},{"name":"Faculty of Medicine, University of Geneva, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,10,10]]},"reference":[{"key":"ref1","volume-title":"Wound Dehiscence","author":"R D Rosen","year":"2021"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1097\/00000658-197903000-00016","article-title":"Abdominal wound dehiscence in gastroenterological surgery","volume":"189","author":"F M Penninckx","year":"1979","journal-title":"Ann 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