{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T21:31:02Z","timestamp":1780695062624,"version":"3.54.1"},"reference-count":35,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wrist Surg"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003We observed several cases of heterotopic bone formation after a 1,2 intercompartmental supraretinacular artery (1,2 ICSRA) distal radius vascularized bone graft (VBG) for the treatment of scaphoid nonunion. This adverse event seems underreported. Knowledge about factors associated with the formation of heterotopic bone after VBGs might help reduce this adverse event.<\/jats:p><jats:p>\n          Purpose\u2003What factors are associated with resected heterotopic bone formation after 1,2 ICSRA distal radius graft for the treatment of scaphoid nonunion?<\/jats:p><jats:p>\n          Patients and Methods\u2003We retrospectively reviewed all patients with a scaphoid nonunion treated with a 1,2 ICSRA distal radius graft between 2008 and 2019 in an urban level 1 trauma center in the Netherlands. We included 42 scaphoid nonunions in 41 people treated with the 1,2 ICSRA graft. We assessed potential correlation with patient, fracture, and treatment demographics.<\/jats:p><jats:p>\n          Results\u2003Heterotopic bone developed in 23 VBGs (55% [23\/42]), of which 5 (12% [5\/42]) were resected. Heterotopic bone was located radially (at the pedicle side) in all participants. Except a longer follow-up time (p\u2009=\u20090.028), we found no variables associated with the development of heterotopic bone formation.<\/jats:p><jats:p>\n          Conclusion\u2003The location of the heterotopic bone at the pedicle site in all cases suggests a potential association with the periosteal strip. Surgeons might consider not to oversize the periosteal strip as a potential method to prevent heterotopic ossification after VBG.<\/jats:p><jats:p>\n          Level of Evidence\u2003Level II, prognostic study.<\/jats:p>","DOI":"10.1055\/s-0043-1771339","type":"journal-article","created":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T22:51:49Z","timestamp":1690584709000},"page":"208-214","source":"Crossref","is-referenced-by-count":2,"title":["Symptomatic Heterotopic Bone Formation after 1,2 ICSRA in Scaphoid Nonunions"],"prefix":"10.1055","volume":"13","author":[{"given":"S. C.","family":"Ghijsen","sequence":"additional","affiliation":[{"name":"Department of Plastic, Reconstructive, and Hand Surgery, University Medical Center Utrecht, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Heeg","sequence":"additional","affiliation":[{"name":"Department of Plastic, Reconstructive, and Hand Surgery, University Medical Center Utrecht, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Teunis","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V. E. C.","family":"den Hollander","sequence":"additional","affiliation":[{"name":"Department of Plastic, Reconstructive, and Hand Surgery, University Medical Center Utrecht, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. H.","family":"Schuurman","sequence":"additional","affiliation":[{"name":"Department of Plastic, Reconstructive, and Hand Surgery, University Medical Center Utrecht, Utrecht, The Netherlands"},{"name":"Department of Plastic, Reconstructive, and Hand Surgery, Central Military Hospital (CMH), Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,7,28]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1016\/S0039-6109(16)39895-4","article-title":"Fractures and dislocations of the carpus","volume":"52","author":"A W Dunn","year":"1972","journal-title":"Surg Clin North Am"},{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1302\/0301-620X.71B2.2925752","article-title":"Patterns of union in fractures of the waist of the scaphoid","volume":"71","author":"J J Dias","year":"1989","journal-title":"J Bone Joint Surg Br"},{"issue":"01","key":"ref3","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1302\/0301-620X.81B1.0810091","article-title":"Acute fractures of the scaphoid. Treatment by cast immobilisation with the wrist in flexion or extension?","volume":"81","author":"J E Hambidge","year":"1999","journal-title":"J Bone Joint Surg Br"},{"issue":"09","key":"ref4","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1016\/j.jhsa.2015.05.003","article-title":"Treatment of scaphoid nonunion: a systematic review of the existing evidence","volume":"40","author":"R M Pinder","year":"2015","journal-title":"J Hand Surg Am"},{"issue":"05","key":"ref5","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1177\/1753193415604778","article-title":"Scaphoid fracture non-union: a systematic review of surgical treatment using bone graft","volume":"41","author":"D O Ferguson","year":"2016","journal-title":"J Hand Surg Eur Vol"},{"issue":"02","key":"ref6","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1142\/S0218810415400043","article-title":"Bone grafts for scaphoid nonunion: an overview","volume":"20","author":"S ER Hovius","year":"2015","journal-title":"Hand Surg"},{"issue":"05","key":"ref7","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1097\/01.prs.0000256144.52654.da","article-title":"Scaphoid nonunions: management with vascularized bone grafts from the distal radius: a clinical and functional outcome study","volume":"119","author":"K N Malizos","year":"2007","journal-title":"Plast Reconstr Surg"},{"issue":"02","key":"ref8","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1007\/s12306-012-0219-y","article-title":"Local distal radius bone graft versus iliac crest bone graft for scaphoid nonunion: a comparative study [published correction appears in Musculoskelet Surg. 2013 Aug;97(2):115. Garg, Bhavuk [removed]; Kotwal, Prakash P [removed]]","volume":"97","author":"T Goyal","year":"2013","journal-title":"Musculoskelet Surg"},{"issue":"02","key":"ref9","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1177\/1558944716643080","article-title":"Vascularized bone grafting in scaphoid nonunion: a review of patient-centered outcomes","volume":"12","author":"R K Alluri","year":"2017","journal-title":"Hand (N Y)"},{"issue":"04","key":"ref10","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1053\/jhsu.2002.34372","article-title":"Treatment of scaphoid nonunions: quantitative meta-analysis of the literature","volume":"27","author":"G A Merrell","year":"2002","journal-title":"J Hand Surg Am"},{"issue":"03","key":"ref11","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1054\/jhsb.2001.0736","article-title":"Management of acute fractures and nonunions of the proximal pole of the scaphoid","volume":"27","author":"H Krimmer","year":"2002","journal-title":"J Hand Surg [Br]"},{"issue":"01","key":"ref12","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0363-5023(79)80101-X","article-title":"Blood vessel transplantation to bone","volume":"4","author":"Y Hori","year":"1979","journal-title":"J Hand Surg Am"},{"issue":"05","key":"ref13","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1302\/0301-620X.70B5.3192587","article-title":"Pronator quadratus pedicled bone graft for old scaphoid fractures","volume":"70","author":"H Kawai","year":"1988","journal-title":"J Bone Joint Surg Br"},{"issue":"06","key":"ref14","doi-asserted-by":"crossref","first-page":"883","DOI":"10.2106\/00004623-199506000-00009","article-title":"Non-union of the scaphoid. Revascularization of the proximal pole with implantation of a vascular bundle and bone-grafting","volume":"77","author":"D L Fernandez","year":"1995","journal-title":"J Bone Joint Surg Am"},{"issue":"03","key":"ref15","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/0363-5023(91)90017-6","article-title":"A new vascularized bone graft for scaphoid nonunion","volume":"16","author":"C Zaidemberg","year":"1991","journal-title":"J Hand Surg Am"},{"issue":"03","key":"ref16","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1097\/00006534-200109010-00010","article-title":"Small free vascularized iliac crest bone grafts in reconstruction of the scaphoid bone: a retrospective study in 60 cases","volume":"108","author":"C Harpf","year":"2001","journal-title":"Plast Reconstr Surg"},{"issue":"03","key":"ref17","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1053\/jhsu.2000.5993","article-title":"Free vascularized bone graft for nonunion of the scaphoid","volume":"25","author":"K Doi","year":"2000","journal-title":"J Hand Surg Am"},{"issue":"05","key":"ref18","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1002\/micr.20670","article-title":"Scaphoid reconstruction by a free vascularized osteochondral graft from the rib: a case report","volume":"29","author":"M Lanzetta","year":"2009","journal-title":"Microsurgery"},{"issue":"01","key":"ref19","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1055\/s-0033-1364092","article-title":"Ectopic bone formation after medial femoral condyle graft to scaphoid nonunion","volume":"3","author":"T Vedung","year":"2014","journal-title":"J Wrist Surg"},{"issue":"03","key":"ref20","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.hansur.2020.12.006","article-title":"Mid-term follow-up of surgically treated and healed scaphoid fractures","volume":"40","author":"P Kaiser","year":"2021","journal-title":"Hand Surg Rehabil"},{"issue":"06","key":"ref21","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1093\/aje\/kwq433","article-title":"Updating and validating the Charlson comorbidity index and score for risk adjustment in hospital discharge abstracts using data from 6 countries","volume":"173","author":"H Quan","year":"2011","journal-title":"Am J Epidemiol"},{"issue":"04","key":"ref22","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/S0749-0712(21)01438-4","article-title":"The anatomy of the scaphoid","volume":"17","author":"R A Berger","year":"2001","journal-title":"Hand Clin"},{"issue":"02","key":"ref23","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/01.sla.0000133083.54934.ae","article-title":"Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey","volume":"240","author":"D Dindo","year":"2004","journal-title":"Ann Surg"},{"issue":"01","key":"ref24","doi-asserted-by":"crossref","first-page":"141","DOI":"10.2214\/ajr.174.1.1740141","article-title":"Usefulness of gadolinium-enhanced MR imaging in the evaluation of the vascularity of scaphoid nonunions","volume":"174","author":"L Cerezal","year":"2000","journal-title":"AJR Am J Roentgenol"},{"issue":"15","key":"ref25","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.2106\/JBJS.20.01945","article-title":"Mental-health phenotypes and patient-reported outcomes in upper-extremity illness","volume":"103","author":"H Miner","year":"2021","journal-title":"J Bone Joint Surg Am"},{"issue":"02","key":"ref26","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/s12593-014-0140-8","article-title":"The correlation of cognitive flexibility with pain intensity and magnitude of disability in upper extremity illness","volume":"6","author":"M G Hageman","year":"2014","journal-title":"J Hand Microsurg"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"110915","DOI":"10.1016\/j.jpsychores.2022.110915","article-title":"Symptoms of depression and catastrophic thinking attenuate the relationship of pain intensity and magnitude of incapability with fracture severity","volume":"158","author":"A Al Salman","year":"2022","journal-title":"J Psychosom Res"},{"issue":"05","key":"ref28","doi-asserted-by":"crossref","first-page":"102972","DOI":"10.1016\/j.otsr.2021.102972","article-title":"Volar rerouting of the 1,2 intercompartmental supraretinacular artery vascularized bone graft for middle and distal scaphoid nonunions","volume":"107","author":"C Chaves","year":"2021","journal-title":"Orthop Traumatol Surg Res"},{"issue":"01","key":"ref29","doi-asserted-by":"crossref","first-page":"86.e1","DOI":"10.1016\/j.jhsa.2021.02.027","article-title":"Vascularized ulnar periosteal pedicled flap for upper extremity reconstruction in adults: a prospective case series of 11 patients","volume":"47","author":"S Barrera-Ochoa","year":"2022","journal-title":"J Hand Surg Am"},{"issue":"12","key":"ref30","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1302\/0301-620X.90B12.20808","article-title":"The use of a vascularised periosteal patch onlay graft in the management of nonunion of the proximal scaphoid","volume":"90","author":"N W Thompson","year":"2008","journal-title":"J Bone Joint Surg Br"},{"issue":"09","key":"ref31","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1002\/adhm.201300012","article-title":"Enhanced osteogenesis by a biomimic pseudo-periosteum-involved tissue engineering strategy","volume":"2","author":"X Shi","year":"2013","journal-title":"Adv Healthc Mater"},{"issue":"06","key":"ref32","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1097\/00000658-191506000-00003","article-title":"The osteogenic power of periosteum: with a note on bone transplantation: an experimental study","volume":"61","author":"J S Davis","year":"1915","journal-title":"Ann Surg"},{"issue":"04","key":"ref33","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1177\/1558944717751191","article-title":"The vascularity and osteogenesis of a vascularized flap for the treatment of scaphoid nonunion: the pedicle volar distal radial periosteal flap","volume":"14","author":"C Tanner","year":"2019","journal-title":"Hand (N Y)"},{"issue":"03","key":"ref34","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1097\/SCS.0000000000001417","article-title":"Effect of periosteum attached to autogenous iliac block bone graft on bone resorption in rabbits","volume":"26","author":"K D Park","year":"2015","journal-title":"J Craniofac Surg"},{"issue":"03","key":"ref35","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1097\/00001665-199407000-00005","article-title":"The effect of periosteal preservation on osteogenesis in a canine rib autograft model: tetracycline fluorescence incident photometry","volume":"5","author":"F D Burstein","year":"1994","journal-title":"J Craniofac Surg"}],"container-title":["Journal of Wrist Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0043-1771339.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T10:55:31Z","timestamp":1730804131000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0043-1771339"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,28]]},"references-count":35,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2024,5,27]]},"published-print":{"date-parts":[[2024,6]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0043-1771339","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2163-3916","2163-3924"],"issn-type":[{"value":"2163-3916","type":"print"},{"value":"2163-3924","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,28]]}}}