{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T23:26:12Z","timestamp":1792020372270,"version":"4.4.0"},"reference-count":9,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T00:00:00Z","timestamp":1702598400000},"content-version":"vor","delay-in-days":14,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian J Neurosurg"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003This study compared intraoperative findings with preoperative computed tomography angiography (CTA) and computational fluid dynamics (CFD) analysis of perianeurysmal findings for the indication of possible vessel wall thinning.<\/jats:p><jats:p>\n          Materials and Methods\u2003Participants comprised 38 patients with unruptured middle cerebral artery aneurysms treated by surgical clipping at our hospital between May 2020 and April 2021. We defined parent artery radiation sign (PARS) as the presence of each of the following three findings in CFD analysis based on preoperative CTA: (1) impingement of the stream line on the outer parent vessel wall of the aneurysm; (2) radiation of wall shear stress vectors outwards from the same site; and (3) increased wall pressure compared with the surrounding area. CFD analysis showing PARS was compared with intraoperative findings.<\/jats:p><jats:p>\n          Results\u2003In all nine cases with PARS, no morphological abnormalities were found in the same area on CTA. However, intraoperative findings showed thinning of the parent artery wall in one of the nine cases and formation of a very small mass in three cases, differing from CTA findings. All nine patients underwent additional clipping and\/or wrapping and coating at the site of PARS.<\/jats:p><jats:p>\n          Conclusion\u2003Detecting thinning of the vessel wall or the presence of a microaneurysm may be difficult in endovascular therapy, which is based on the visualization of the vessel lumen. CFD analysis suggests the necessity of confirming findings for the vessel wall around an aneurysm by direct manipulation, as the presence of PARS may indicate partial thinning of the vessel wall or formation of a microaneurysm.<\/jats:p>","DOI":"10.1055\/s-0043-1771367","type":"journal-article","created":{"date-parts":[[2023,12,16]],"date-time":"2023-12-16T00:10:52Z","timestamp":1702685452000},"page":"764-768","source":"Crossref","is-referenced-by-count":4,"title":["Predicting Morphological Changes to Vessel Walls Adjacent to Unruptured Cerebral Aneurysms Using Computational Fluid Dynamics"],"prefix":"10.1055","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8456-0560","authenticated-orcid":false,"given":"Kento","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fujita Health University, Bantane Hospital, Nagoya, Aichi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4960-9402","authenticated-orcid":false,"given":"Fuminari","family":"Komatsu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fujita Health University, Bantane Hospital, Nagoya, Aichi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyosuke","family":"Miyatani","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fujita Health University, Bantane Hospital, Nagoya, Aichi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riki","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fujita Health University, Bantane Hospital, Nagoya, Aichi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fujita Health University, Bantane Hospital, Nagoya, Aichi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoko","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fujita Health University, Bantane Hospital, Nagoya, Aichi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuichi","family":"Hirose","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fujita Health University, Toyoake, Aichi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,12,15]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.3174\/ajnr.A4699","article-title":"Current trends and results of endovascular treatment of unruptured intracranial aneurysms at a single institution in the flow-diverter era","volume":"37","author":"O Petr","year":"2016","journal-title":"AJNR Am J 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emphasis on sex, age, comorbidity, country, and time period: a systematic review and meta-analysis","volume":"10","author":"M H Vlak","year":"2011","journal-title":"Lancet Neurol"},{"issue":"06","key":"ref9","doi-asserted-by":"crossref","first-page":"061009","DOI":"10.1115\/1.4033477","article-title":"Flow instability detected by high-resolution computational fluid dynamics in fifty-six middle cerebral artery aneurysms","volume":"138","author":"N Varble","year":"2016","journal-title":"Biomech Eng"}],"container-title":["Asian Journal of 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