{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T03:11:27Z","timestamp":1789182687999,"version":"build-2803163510"},"reference-count":16,"publisher":"Scientific Scholar","issue":"04","license":[{"start":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T00:00:00Z","timestamp":1690502400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["South Asian J Cancer"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Telangiectatic osteosarcoma is an uncommon subtype of osteosarcoma accounting for less than 4% of all cases of osteosarcoma. It is characterized by distinctive radiographic, pathologic features, and prognostic implications. Radiologically and microscopically, it mimics aneurysmal bone cyst. The objective of this study was to study the clinical profile and treatment outcome of patients with telangiectatic osteosarcoma. Thirteen patients were diagnosed with telangiectatic osteosarcoma in the department of medical oncology at a tertiary cancer center in India during a 12-year period. All patients were above 15 years of age. The median age at presentation was 20 years, males were predominant, and the commonest sites of involvement were lower end of femur and upper end of humerus. Ten patients underwent treatment that consisted of neoadjuvant and\/or adjuvant chemotherapy with ifosfamide, doxorubicin, cisplatin regimen and limb sparing surgery or amputation. Currently, eight out of ten patients are alive in remission at a median follow-up of 50 months with survival ranging from 18 to 138 months.<\/jats:p>","DOI":"10.1055\/s-0043-1771386","type":"journal-article","created":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T19:04:12Z","timestamp":1690571052000},"page":"703-710","source":"Crossref","is-referenced-by-count":1,"title":["Telangiectatic Osteosarcoma\u2014A Single-Center Experience"],"prefix":"10.25259","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0345-6623","authenticated-orcid":false,"given":"Geetha","family":"Narayanan","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Regional Cancer Centre, Trivandrum, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sugeeth M","family":"Thambi","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Regional Cancer Centre, Trivandrum, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayasree","family":"Kattoor","sequence":"additional","affiliation":[{"name":"Department of Pathology, Regional Cancer Centre, Trivandrum, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhaskar Subin","family":"Sugath","sequence":"additional","affiliation":[{"name":"Department of Surgical Services, Regional Cancer Centre, Trivandrum, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sreejith G.","family":"Nair","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Regional Cancer Centre, Trivandrum, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2023,7,28]]},"reference":[{"issue":"05","key":"ref1","doi-asserted-by":"crossref","first-page":"572","DOI":"10.5858\/arpa.2011-0204-RS","article-title":"Telangiectatic osteosarcoma","volume":"136","author":"N A Sangle","year":"2012","journal-title":"Arch Pathol Lab Med"},{"issue":"04","key":"ref2","doi-asserted-by":"crossref","first-page":"373","DOI":"10.3171\/2011.12.SPINE111037","article-title":"Primary telangiectatic osteosarcoma of the cervical spine","volume":"16","author":"M K Turel","year":"2012","journal-title":"J Neurosurg Spine"},{"issue":"06","key":"ref3","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1148\/rg.306105524","article-title":"Imaging characteristics of primary osteosarcoma: nonconventional subtypes","volume":"30","author":"G Yarmish","year":"2010","journal-title":"Radiographics"},{"issue":"10","key":"ref4","doi-asserted-by":"crossref","first-page":"3014","DOI":"10.1002\/1097-0142(19930515)71:10<3014::AID-CNCR2820711021>3.0.CO;2-8","article-title":"Extraskeletal telangiectatic osteosarcoma","volume":"71","author":"J M Mirra","year":"1993","journal-title":"Cancer"},{"issue":"02","key":"ref5","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1148\/radiol.2292021130","article-title":"Telangiectatic osteosarcoma: radiologic-pathologic comparison","volume":"229","author":"M D Murphey","year":"2003","journal-title":"Radiology"},{"issue":"01","key":"ref6","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.jnci.2018.01.006","article-title":"Osteosarcoma subtypes: Magnetic resonance and quantitative diffusion weighted imaging criteria","volume":"30","author":"R Zeitoun","year":"2018","journal-title":"J Egypt Natl Canc Inst"},{"issue":"05","key":"ref7","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/0959-8049(94)90532-0","article-title":"Primary chemotherapy and delayed surgery for non-metastatic telangiectatic osteosarcoma of the extremities. 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