{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T17:29:38Z","timestamp":1775064578051,"version":"3.50.1"},"reference-count":44,"publisher":"Georg Thieme Verlag KG","issue":"S 01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>\n            Objective\u2003Our study aimed to determine the relationship between maternal diabetes mellitus (MDM) and mortality and major morbidities for very preterm infants, as well as the effects of insulin-treated MDM, in the Chinese population.<\/jats:p><jats:p>\n            Study Design\u2003This retrospective cohort study included all preterm infants born at 240\/7 to 316\/7 weeks of gestation and admitted to 57 tertiary neonatal intensive care units participating in the Chinese Neonatal Network in 2019. All infants were followed up until discharging from the hospitals.<\/jats:p><jats:p>\n            Results\u2003A total of 9,244 very preterm infants were enrolled, with 1,584 (17.1%) born to mothers with MDM. The rates of mortality or any major morbidity in the MDM and non-MDM groups were 45.9% (727\/1,584) and 48.1% (3,682\/7,660), respectively. After adjustment, the risk of mortality or any morbidity was not significantly increased in the MDM group (adjusted odds ratio [aOR], 1.07; 95% confidence interval [CI], 0.94\u20131.22) compared with the non-MDM group. Among MDM mothers with treatment data, 18.0% (256\/1,420) were treated with insulin. Insulin-treated MDM was not independently associated with the risk of mortality or any morbidity (aOR, 1.01; 95% CI, 0.76\u20131.34) among very preterm infants, but it was associated with an elevated risk of severe retinopathy of prematurity (aOR, 2.39; 95% CI, 1.13\u20135.04).<\/jats:p><jats:p>\n            Conclusion\u2003While the MDM diagnostic rate for mothers of very preterm infants was high in China, MDM was not associated with mortality or major morbidities for very preterm infants.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0043-1771501","type":"journal-article","created":{"date-parts":[[2023,8,14]],"date-time":"2023-08-14T22:51:38Z","timestamp":1692053498000},"page":"e2474-e2484","source":"Crossref","is-referenced-by-count":5,"special_numbering":"S","title":["Impact of Maternal Diabetes Mellitus on Neonatal Outcomes among Infants &lt;32 Weeks of Gestation in China: A Multicenter Cohort Study"],"prefix":"10.1055","volume":"41","author":[{"given":"Jing","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Qingdao Women and Children's Hospital, Qingdao, Shandong Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinyue","family":"Gu","sequence":"additional","affiliation":[{"name":"NHC Key Laboratory of Neonatal Diseases (Fudan University), Children's Hospital of Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Guangdong Women and Children's Hospital, Guangzhou, Guangdong Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinzhu","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Women and Children's Hospital, School of Medicine, Xiamen University, Xiamen, Fujian Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingfei","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Children's Hospital of Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siyuan","family":"Jiang","sequence":"additional","affiliation":[{"name":"NHC Key Laboratory of Neonatal Diseases (Fudan University), Children's Hospital of Fudan University, Shanghai, China"},{"name":"Department of Neonatology, Children's Hospital of Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lizhong","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Children's Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenhao","family":"Zhou","sequence":"additional","affiliation":[{"name":"NHC Key Laboratory of Neonatal Diseases (Fudan University), Children's Hospital of Fudan University, Shanghai, China"},{"name":"Department of Neonatology, Children's Hospital of Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun","family":"Cao","sequence":"additional","affiliation":[{"name":"NHC Key Laboratory of Neonatal Diseases (Fudan University), Children's Hospital of Fudan University, Shanghai, China"},{"name":"Department of Neonatology, Children's Hospital of Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoo K.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Mount Sinai Hospital, Toronto, Canada"},{"name":"Department of Pediatrics, University of Toronto, Toronto, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruobing","family":"Shan","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Qingdao Women and Children's Hospital, Qingdao, Shandong Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lan","family":"Zhang","sequence":"additional","affiliation":[{"name":"NHC Key Laboratory of Neonatal Diseases (Fudan University), Children's Hospital of Fudan University, Shanghai, China"},{"name":"Department of Neonatology, Children's Hospital of Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the Chinese Neonatal Network","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,8,14]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/j.beem.2011.07.009","article-title":"Pregnancy and diabetes","volume":"25","author":"D R McCance","year":"2011","journal-title":"Best Pract Res Clin Endocrinol 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