{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T00:53:06Z","timestamp":1767919986129,"version":"3.49.0"},"reference-count":19,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2023,8,11]],"date-time":"2023-08-11T00:00:00Z","timestamp":1691712000000},"content-version":"vor","delay-in-days":41,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg Rep"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Clival chordoma is a rare, aggressive, notochord-derived tumor primarily managed with surgery via an endoscopic endonasal approach (EEA) and adjuvant proton beam radiotherapy. Reconstruction is commonly performed with a nasoseptal flap (NSF) at the time of initial surgery. While failures of the NSF are rare, they can occur following the initial surgery or in the setting of osteoradionecrosis. Salvage repair typically requires transfer of alternative vascularized tissues outside of the previously radiated field including regional scalp flaps such as pericranial or temporoparietal fascial flaps, or free vascularized tissue transfer. Here we describe the case of a 29-year-old woman with a history of clival chordoma with widespread skull base osteomyelitis secondary to NSF necrosis after proton beam radiotherapy. We describe successful skull base reconstruction with intranasal bilateral inferior turbinate flaps based on the sphenopalatine artery with lateral nasal wall extension, despite prior proton beam therapy and a failed prior vascularized intranasal reconstruction.<\/jats:p>","DOI":"10.1055\/s-0043-1772200","type":"journal-article","created":{"date-parts":[[2023,8,11]],"date-time":"2023-08-11T23:32:23Z","timestamp":1691796743000},"page":"e87-e91","source":"Crossref","is-referenced-by-count":4,"title":["Bilateral Inferior Turbinate Flaps for Salvage Reconstruction after Proton Beam Radiotherapy for Clival Chordoma"],"prefix":"10.1055","volume":"84","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8744-7168","authenticated-orcid":false,"given":"Kayva L.","family":"Crawford","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head & Neck Surgery, University of California San Diego, La Jolla, California, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megana","family":"Saripella","sequence":"additional","affiliation":[{"name":"School of Medicine, University of California San Diego, La Jolla, California, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam S.","family":"DeConde","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head & Neck Surgery, University of California San Diego, La Jolla, California, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas L.","family":"Beaumont","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of California San Diego, La Jolla, California, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,8,11]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1023\/A:1008947301735","article-title":"Chordoma: incidence and survival patterns in the United States, 1973-1995","volume":"12","author":"M L McMaster","year":"2001","journal-title":"Cancer Causes Control"},{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"e69","DOI":"10.1016\/S1470-2045(11)70337-0","article-title":"Chordoma: current concepts, management, and future directions","volume":"13","author":"B P Walcott","year":"2012","journal-title":"Lancet Oncol"},{"issue":"04","key":"ref3","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.neucir.2018.03.004","article-title":"Extended endoscopic endonasal surgery for clival chordoma and chondrosarcoma: our experience in 14 cases","volume":"29","author":"D 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