{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T10:26:20Z","timestamp":1788690380003,"version":"build-2803163510"},"reference-count":47,"publisher":"Georg Thieme Verlag KG","issue":"S 01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>\n            Objective\u2003Trisomy 13 (T13) and 18 (T18) are aneuploidies associated with multiple structural congenital anomalies and high rates of fetal demise and neonatal mortality. Historically, patients with either one of these diagnoses have been treated similarly with exclusive comfort care rather than invasive interventions or intensive care, despite a wide phenotypic variation and substantial variations in survival length. However, surgical interventions have been on the rise in this population in recent years without clearly elucidated selection criterion. Our objective was to create a standardized approach to counseling expectant persons and parents of newborns with T13\/T18 in order to provide collaborative and consistent counseling and thoughtful approach to interventions such as surgery.<\/jats:p><jats:p>\n            Study Design\u2003This article describes our process and presents our resulting clinical care guideline.<\/jats:p><jats:p>\n            Results\u2003We formed a multi- and interdisciplinary committee. We used published literature when available and otherwise expert opinion to develop an approach to care featuring individualized assessment of the patient to estimate qualitative mortality risk and potential to benefit from intensive care and\/or surgeries centered within an ethical framework.<\/jats:p><jats:p>\n            Conclusion\u2003Through multidisciplinary collaboration, we successfully created a patient-centered approach for counseling families facing a diagnosis of T13\/T18. Other institutions may use our approach as a model for developing their own standardized approach.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0043-1772748","type":"journal-article","created":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T22:55:21Z","timestamp":1692917721000},"page":"e2666-e2673","source":"Crossref","is-referenced-by-count":3,"special_numbering":"S","title":["Structured Framework for Multidisciplinary Parent Counseling and Medical Interventions for Fetuses and Infants with Trisomy 13 or Trisomy 18"],"prefix":"10.1055","volume":"41","author":[{"given":"Amanda J.H.","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Oregon Health and Science University, Portland, Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayme","family":"Marshall","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Oregon Health and Science University, Portland, Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ladawna","family":"Gievers","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Oregon Health and Science University, Portland, Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tyler","family":"Tate","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Oregon Health and Science University, Portland, Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Taub","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Oregon Health and Science University, Portland, Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Dukhovny","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Ronai","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Oregon Health and Science University, Portland, Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin J.","family":"Madriago","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Oregon Health and Science University, Portland, Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,8,24]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1001\/jama.2016.9819","article-title":"Survival and surgical interventions for children with Trisomy 13 and 18","volume":"316","author":"K E Nelson","year":"2016","journal-title":"JAMA"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1007\/s00431-019-03531-4","article-title":"Ethical issues 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