{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T09:01:48Z","timestamp":1768035708927,"version":"3.49.0"},"reference-count":18,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T00:00:00Z","timestamp":1694563200000},"content-version":"vor","delay-in-days":12,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian J Neurosurg"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003There are a large number of prospective studies that use diffusion tensor imaging (DTI) to show the relationship between intracranial tumors and white matter (WM) fibers. We studied the role of DTI in supratentorial intra-axial (ST-IA) tumors of the brain in deciding the surgical approach with maximal resection and minimal or no deficit and in predicting the histological characterization of the tumor and the neurological outcome.<\/jats:p><jats:p>\n          Methods\u2003A total of 91 cases of ST-IA tumors were included in our study. The neurological status of the patients was assessed preoperatively, and the tumor volume and DTI pattern were noted radiologically. Surgical plan was decided by the senior consultants of the neurosurgery department taking into consideration the findings of tractography and magnetic resonance imaging. The neurological status and the extent of resection were evaluated postoperatively, and the correlation between histopathology with DTI was studied.<\/jats:p><jats:p>\n          Results\u2003Of the 91 patients, 25 had high-grade glioma (HGG), 60 had low-grade glioma (LGG), and 6 were metastatic lesions. Gross total excisions were done mostly in patients with DTI showing displaced fibers and subtotal\/partial resections were done mostly in disrupted\/infiltrated tracts, which was statistically significant. The correlation between histopathology and tractography revealed that intact\/displaced tracts were seen mostly in LGG (79%), whereas 86% of HGG showed disrupted\/infiltrated fibers; both were statistically significant.<\/jats:p><jats:p>\n          Conclusion\u2003Preoperative DTI in ST-IA brain tumors is an important tool for deciding the appropriate surgical approach for maximal safe resection, thus improving the post-op neurological outcome in patients. It also helps in predicting the tumor histology while also serving as an important prognostication indicator.<\/jats:p>","DOI":"10.1055\/s-0043-1772758","type":"journal-article","created":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T23:02:53Z","timestamp":1694646173000},"page":"476-483","source":"Crossref","is-referenced-by-count":1,"title":["Preoperative Diffusion Tensor Imaging in Supratentorial Intra-Axial Brain Tumors: Its Role in Predicting Tumor Histology and Prognosis as well in Surgical Planning and Resection"],"prefix":"10.1055","volume":"18","author":[{"given":"Ajay","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, SMS Medical College and Hospital, Jaipur, Rajasthan, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaurav","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, SMS Medical College and Hospital, Jaipur, Rajasthan, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vinod","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, SMS Medical College and Hospital, Jaipur, Rajasthan, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaveta","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, SMS Medical College and Hospital, Jaipur, Rajasthan, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,9,13]]},"reference":[{"issue":"05","key":"ref1","first-page":"901","article-title":"Posttherapeutic intraaxial brain tumor: the value of perfusion-sensitive contrast-enhanced MR imaging for differentiating tumor recurrence from nonneoplastic contrast-enhancing tissue","volume":"21","author":"T Sugahara","year":"2000","journal-title":"AJNR Am J 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Field","year":"2004","journal-title":"J Magn Reson Imaging"},{"issue":"02","key":"ref14","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1093\/neuonc\/nor188","article-title":"Role of diffusion tensor magnetic resonance tractography in predicting the extent of resection in glioma surgery","volume":"14","author":"A Castellano","year":"2012","journal-title":"Neuro Oncol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"e540","DOI":"10.1016\/j.wneu.2018.12.146","article-title":"Preoperative diffusion tensor imaging: a landmark modality for predicting the outcome and characterization of supratentorial intra-axial brain tumors","volume":"124","author":"K A Khan","year":"2019","journal-title":"World Neurosurg"},{"issue":"06","key":"ref16","first-page":"1081","article-title":"The role of diffusion-weighted imaging in patients with brain tumors","volume":"22","author":"K Kono","year":"2001","journal-title":"AJNR Am J 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