{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:21:59Z","timestamp":1791332519363,"version":"4.3.1"},"reference-count":72,"publisher":"Georg Thieme Verlag KG","issue":"11","license":[{"start":{"date-parts":[[2023,10,29]],"date-time":"2023-10-29T00:00:00Z","timestamp":1698537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Neuropsiquiatr"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background\u2003Parkinson's disease (PD) may progressively reduce the upper limb's functionality. Currently, there is no standardized upper limb functional capacity assessment in PD in the rehabilitation field.<\/jats:p>\n                  <jats:p>Objective\u2003To identify specific outcome measurements to assess upper limbs in PD and access functional capacity.<\/jats:p>\n                  <jats:p>Methods\u2003We systematically reviewed and analyzed the literature in English published from August\/2012 to August\/2022 according to PRISMA. The following keywords were used in our search: \u201cupper limbs\u201d OR \u201cupper extremity\u201d and \u201cParkinson's disease.\u201d Two researchers searched independently, including studies accordingly to our inclusion and exclusion criteria. Registered at PROSPERO CRD42021254486.<\/jats:p>\n                  <jats:p>Results\u2003We found 797 studies, and 50 were included in this review (n\u2009=\u20092.239 participants in H&amp;Y stage 1\u20134). The most common upper limbs outcome measures found in the studies were: (i) UPDRS-III and MDS-UPDRS to assess the severity and progression of PD motor symptoms (tremor, bradykinesia, and rigidity) (ii) Nine Hole Peg Test and Purdue Pegboard Test to assess manual dexterity; (iii) Spiral test and Funnel test to provoke and assess freezing of upper limbs; (iv) Technology assessment such as wearables sensors, apps, and other device were also found.<\/jats:p>\n                  <jats:p>Conclusion\u2003We found evidence to support upper limb impairments assessments in PD. However, there is still a large shortage of specific tests to assess the functional capacity of the upper limbs. The upper limbs' functional capacity is insufficiently investigated during the clinical and rehabilitation examination due to a lack of specific outcome measures to assess functionality.<\/jats:p>","DOI":"10.1055\/s-0043-1772769","type":"journal-article","created":{"date-parts":[[2023,10,29]],"date-time":"2023-10-29T19:37:35Z","timestamp":1698608255000},"page":"1008-1015","source":"Crossref","is-referenced-by-count":19,"title":["Clinical assessment of upper limb impairments and functional capacity in Parkinson's disease: a systematic review"],"prefix":"10.1055","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4235-4141","authenticated-orcid":false,"given":"Tamine T. C.","family":"Capato","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Faculdade de Medicina, Departamento de Neurologia, Centro de Dist\u00farbios do Movimento, S\u00e3o Paulo SP, Brazil."},{"name":"Radboud University Medical Centre, Donders Institute for Brain, Cognition and Behavior, Department of Neurology, Nijmegen, The Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2443-9614","authenticated-orcid":false,"given":"R\u00fabia","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Faculdade de Medicina, Departamento de Neurologia, Centro de Dist\u00farbios do Movimento, S\u00e3o Paulo SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6305-3327","authenticated-orcid":false,"given":"Rubens G.","family":"Cury","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Faculdade de Medicina, Departamento de Neurologia, Centro de Dist\u00farbios do Movimento, S\u00e3o Paulo SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7974-6045","authenticated-orcid":false,"given":"Manoel Jacobsen","family":"Teixeira","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Departamento de Neurocirurgia, S\u00e3o Paulo SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6996-9130","authenticated-orcid":false,"given":"Egberto R.","family":"Barbosa","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Faculdade de Medicina, Departamento de Neurologia, Centro de Dist\u00farbios do Movimento, S\u00e3o Paulo SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,10,29]]},"reference":[{"issue":"08","key":"ref1","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1002\/mds.27372","article-title":"International Parkinson and movement disorder society evidence-based medicine review: Update on treatments for the motor symptoms of Parkinson's disease","volume":"33","author":"S H Fox","year":"2018","journal-title":"Mov Disord"},{"issue":"09","key":"ref2","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1001\/jamaneurol.2018.1264","article-title":"Current Concepts in Diagnosis and Treatment of Functional Neurological Disorders","volume":"75","author":"A J Espay","year":"2018","journal-title":"JAMA Neurol"},{"issue":"06","key":"ref3","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1001\/jama.2019.22360","article-title":"Diagnosis and Treatment of Parkinson Disease: A Review","volume":"323","author":"M J Armstrong","year":"2020","journal-title":"JAMA"},{"issue":"12","key":"ref4","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1002\/mds.26424","article-title":"MDS clinical diagnostic criteria for Parkinson's disease","volume":"30","author":"R B Postuma","year":"2015","journal-title":"Mov Disord"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"2284","DOI":"10.1016\/S0140-6736(21)00218-X","article-title":"Parkinson's disease","volume":"397","author":"B R Bloem","year":"2021","journal-title":"Lancet"},{"issue":"10","key":"ref6","doi-asserted-by":"crossref","first-page":"2423","DOI":"10.1007\/s10439-017-1881-x","article-title":"Quantification of Hand Motor Symptoms in Parkinson's Disease: A Proof-of-Principle Study Using Inertial and Force Sensors","volume":"45","author":"J C van den Noort","year":"2017","journal-title":"Ann Biomed Eng"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.jns.2017.08.3246","article-title":"Tremor's glove-an innovative electrical muscle stimulation therapy for intractable tremor in Parkinson's disease: A randomized sham-controlled trial","volume":"381","author":"O Jitkritsadakul","year":"2017","journal-title":"J Neurol Sci"},{"key":"ref9","first-page":"168","volume-title":"Capato TTdC. 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